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SELF-ASSESSMENT QUESTIONS
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1. For which of the following is a bone marrow biopsy most important as part of the initial evaluation?
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C. Evaluation for an autoimmune disorder
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D. Recurrent infections in the presence of a normal white blood cell count
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The correct answer is A. Lymph node biopsy is more relevant to the initial evaluation for lymphoma than a bone marrow biopsy. An initial evaluation for autoimmunity is an antinuclear antibody test, with no indication at initial presentation for a bone marrow biopsy. Recurrent infections in the presence of a normal white blood cell count direct an initial evaluation to white blood cell function.
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2. In which of the following disorders is an increase in circulating eosinophils not commonly found?
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B. Selected parasitic infections
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D. Acute lymphocytic leukemia
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The correct answer is D. Acute lymphocytic leukemia is associated with large amounts of lymphocytes with no excess of eosinophils. All of the other choices have strong associations to eosinophilia.
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3. Which of the following is a differentiating feature for Hodgkin and against non-Hodgkin lymphoma?
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A. There is a much larger variety of lymphoma types
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B. Proliferating cells spread widely and noncontiguously
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C. Mesenteric lymph nodes commonly involved
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D. Typically, involvement of a single group of lymph nodes only, such as the mediastinal lymph nodes
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The correct answer is D. In Hodgkin lymphoma, proliferating cells spread by contiguity, mesenteric lymph nodes are rarely involved, and there are fewer types than in non-Hodgkin lymphomas.
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4. Which of the following leukemias is most common in young children?
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A. Chronic lymphocytic leukemia
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B. Acute myelocytic leukemia
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C. Chronic myelocytic leukemia
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D. Acute lymphocytic leukemia
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The correct answer is D. Acute lymphocytic leukemia is very common in young children, with a high cure rate.
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5. Which of the following has a median age at diagnosis of approximately 70 years?
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A. Chronic lymphocytic leukemia
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B. Acute myelocytic leukemia
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C. Chronic myelocytic leukemia
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D. Acute lymphocytic leukemia
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