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SELF-ASSESSMENT QUESTIONS

1. After a unit of whole blood is collected from a normal donor for transfusion, which step in the processing of the whole blood happens next?

A. Testing of blood for infectious disease

B. Blood component preparation

C. Assessment of donor–recipient compatibility

D. Treatment of the blood product to minimize potential adverse effects

The correct answer is B. The steps are in the order—B, A, C and then D.

2. One unit of which of the following blood component restores the largest number and amount of plasma proteins?

A. Packed red blood cells

B. Fresh frozen plasma

C. Cryoprecipitate

D. Platelet concentrate (whole blood derived)

The correct answer is B. There is a small amount of plasma in packed red blood cells and in random donor platelet products. Cryoprecipitate contains a very limited number of plasma proteins. Fresh frozen plasma contains all of the proteins found in normal human plasma.

3. Which of the following blood components is stored at room temperature?

A. Packed red blood cells

B. Fresh frozen plasma

C. Platelets—both concentrates from whole blood and apheresis

D. Cryoprecipitate

The correct answer is C. Platelets are stored at 20°C to 24°C. Packed red blood cells are stored at 1°C to 6°C. Fresh frozen plasma can be stored at less than –18°C for 1 year or at less than –65°C for 7 years. The same is true for cryoprecipitate.

4. Which of the following blood components can be used to increase the circulating concentration of coagulation factors in the recipient?

A. Packed red blood cells

B. Fresh frozen plasma

C. Platelets—both random donor and single donor

D. Cryoprecipitate

The correct answer is B, with the assumption that it has been processed correctly and frozen within 8 hours of blood collection. This preserves the labile coagulation factors, particularly factor V and factor VIII. Cryoprecipitate contains the coagulation factor fibrinogen, and coagulation factor VIII along with von Willebrand factor. The other coagulation factors are missing or in very low concentration in cryoprecipitate. The coagulation factors are not preserved at 1°C to 6°C, the storage temperature for packed red blood cells, or at 20°C to 24°C, the storage temperature ...

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