1. Which one of the following parameters of the complete blood count does not provide a measurement of red blood cell quantity?
C. Mean corpuscular volume (MCV)
The correct answer is C. The MCV is a measure of red blood cell size. All of the others are measures of red blood cell quantity.
2. All but one of the following is an anemia associated with a defect in the maturation of the red blood cell. Which of the following is not associated with a maturation defect?
D. Immune hemolytic anemia
The correct answer is D. Immune hemolytic anemia does not involve reduced proliferation of red blood cells. Immune hemolytic anemia is produced by antibody-mediated red blood cell destruction.
3. Which of the following causes of anemia is not associated with a high value for MCV?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
The correct answer is B. Iron-deficiency anemia is a very common cause for small red blood cells with a low MCV value. All of the other choices are associated with the presence of a larger than normal red blood cells.
4. Which one of the four choices below corresponds to the description of the following inclusion in red blood cells?
In a Wright stain peripheral blood smear, the inclusions are blue dots within red cells that are larger than basophilic stippling and represent iron-containing mitochondria; they are commonly found in patients who are asplenic.
The correct answer is B. Heinz bodies are gray-black round inclusions, seen only with supravital stains such as crystal violet. They are found in patients with certain unstable hemoglobins. Howell–Jolly bodies are dot-like, dark purple inclusions, unlike Pappenheimer bodies that are more irregular and more gray. Cabot rings are ring-shaped dark purple inclusions. Like Howell–Jolly bodies, they represent residual nuclear fragments.
5. Which one of the four choices below corresponds to the description of ...