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Endocrine Disorders

During pregnancy TSH receptors are weakly cross stimulated by _____ which is produced in the ____.

a. AFP, trophoblast

b. β-hCG, trophoblast

c. AFP, syncytiotrophoblast

d. β-hCG, syncytiotrophoblast

When does the fetus begin to concentrate and synthesize thyroid hormone?

a. 8 weeks

b. 10 week

c. 12 weeks

d. 14 weeks

Thyroid-stimulating immunoglobulins are usually associated with which entity listed below?

a. Graves disease

b. Thyroid peroxidase

c. Fetal micro-chimerism

d. None of the above

The main cause of thyrotoxicosis in pregnancy is which of the following?

a. Graves disease

b. Type 1 diabetes

c. Multiple gestations

d. Methamphetamine toxicity

The American Thyroid Association recommends which of the following therapy strategies for hyperthyroidism?

a. 1st and 2nd trimesters: methimazole; 3rd trimester: propylthiouracil

b. 1st trimester: methimazole; 2nd and 3rd trimesters: propylthiouracil

c. 1st and 2nd trimesters: propylthiouracil; 3rd trimester: methimazole

d. 1st trimester: propylthiouracil; 2nd and 3rd trimesters: methimazole

After beginning propylthiouracil treatment, how often should you evaluate free T4 levels?

a. Every 2 weeks

b. Every 3 weeks

c. Every trimester

d. Every 4–6 weeks

All except which of the following congenital defects are associated with methimazole embryopathy?

a. Aplasia cutis

b. Choanal atresia


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