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Appendix A

Appendix A

Table A–1.

Summary of major reabsorption and secretion events by major tubular segments

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Table A–1.

Summary of major reabsorption and secretion events by major tubular segments
Proximal tubule Loop of Henle Distal tubule Collecting ducts
Organic nutrients R
Urea R S R
Proteins, peptides R
Phosphate R
Sulfate R
Organic anions* S
Organic cations* S
Urate R (mostly) and S
Sodium R R R R
Chloride R R R R
Potassium R R S (usually) and R
Water R R R
Hydrogen ions S S S or R
Bicarbonate R R S or R
Ammonium S R S
Calcium R R R

*Some passive transport may occur in the distal nephron depending on pH.

Table A–2.

Major functions of the various collecting-duct cells

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Table A–2.

Major functions of the various collecting-duct cells
Principal cells

  1. Reabsorb sodium

  2. Secrete potassium

  3. Reabsorb water
Type A intercalated cells

  1. Secrete hydrogen ions

  2. Reabsorb or secrete potassium
Type B intercalated cells

  1. Secrete bicarbonate
Inner medullary cells

  1. Reabsorb urea

  2. Secrete ammonia/ammonium

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