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Patients who seek medical care after self-administering mind-altering substances may have used any of a large variety of compounds. Several of these agents are discussed elsewhere in this manual (eg, amphetamines, cocaine, marijuana, phencyclidine and ketamine, and toluene). Many of the drugs discussed in this chapter are entactogens ("to touch within"), enhancing sensations and promoting illusions (eg, LSD, MDMA). Others have primarily sympathomimetic characteristics, with hallucinations a smaller part of the overall experience (eg, cathinones, PMA). Several have been used widely for personal experimentation as well as clinically to facilitate psychotherapy. Although the use of traditional hallucinogens such as LSD has declined over the past decades, there is a current resurgence of hallucinogen use from novel compounds, such as the 2C-NBOMe series and synthetic cathinones. Table II–35 lists some common and uncommon hallucinogens.


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