CHAPTER 45: Surgeries for Pelvic Floor Disorders

During gynecologic surgery, the lower urinary tract may be injured. Thus, diagnostic cystoscopic evaluation is often warranted following procedures in which the bladder and ureters have been placed at risk. Additionally, operative cystoscopy is within the scope of many gynecologists for the passage of ureteral stents, lesion biopsy, and foreign-body removal. Of these, ureteral stenting may be indicated to delineate the ureter’s course during cases with abnormal pelvic anatomy or to assess ureteral patency following gynecologic surgery.

Rigid and flexible cystoscopes are available, although in gynecology, a rigid scope is typically used. A cystoscope is composed of an outer sheath, bridge, endoscope, and obturator. The sheath contains one port for fluid infusion and a second port for fluid egress. For office cystoscopy, a sheath measuring 17F affords greater comfort. However, for operative cases, a 21F or wider-diameter cystoscope is preferred to allow rapid fluid infusion and easier instrument and stent passage. The sheath’s end tapers, and in women- with a narrow urethral meatus, an obturator can be placed inside the sheath to create a rounded tip for smooth introduction. In selected instances, gentle dilation of the external urethral opening using narrow cervical dilators is needed prior to sheath introduction. The next piece, the bridge, attaches to the proximal portion of the sheath and allows coupling between the endoscope and sheath. Additional ports are present on the bridge and are generally used to introduce stents or instruments.

Several endoscope viewing angles are available and include 0-, 30-, and 70-degree optical views (Fig. 45-1.1). Zero-degree endoscopes are used for urethroscopy. For cystoscopy, a 70-degree endoscope is superior for providing the most comprehensive view of the lateral, anterior, and posterior walls; trigone; and ureteral orifices. To achieve a comparable view, a 30-degree endoscope requires additional manipulation. However, a 30-degree endoscope does offer advantages and allows surgeons greater flexibility as it can be used for either urethroscopy or cystoscopy during a given examination. For operative cystoscopic cases in which instruments are passed down the sheath, a 30-degree endoscope should be used because with 0- and 70-degree endoscopes, operative instruments generally lie outside the field of view.

PREOPERATIVE

Prior to office cystoscopy, urinary tract infection (UTI) is excluded to avoid upper tract infection. If diagnostic cystoscopy is performed properly, complications are rare. Of these, infection is the most common and results from the significant incidence of bacteriuria following cystoscopy.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

Cystoscopy may be performed in low or standard lithotomy position with the legs positioned in stirrups. For office cystoscopy, 2-percent lidocaine jelly is instilled into the urethra 5 to 10 minutes prior to cystoscope insertion. For operative procedures, an additional 50 mL of 4-percent lidocaine solution may be instilled via catheter into the bladder. The perineum and urethral meatus are surgically prepared prior to urethral manipulation.

Distention Media

The bladder must be adequately distended to fully visualize all surfaces, and for diagnostic purposes, saline or sterile water is suitable. To ensure adequate medium flow, an infusion bag is elevated significantly above the level of the symphysis. The volume needed may vary but is reached when bladder walls are not collapsing inward. Overdistending the bladder is also avoided as it may result in temporary urinary retention. If the bladder is distended beyond its capacity, excess fluid will leak out the urethral meatus and around the cystoscope rather than rupturing the bladder, which is rare.

Indigo Carmine

If intraoperative cystoscopy is performed to document ureteral patency, ½ to 1 ampule of indigo carmine is administered intravenously prior to the procedure to aid visualization of urine jets. Less commonly, methylene blue may be used instead but carries the risk of methemoglobinemia in patients with glucose-6-phosphate dehydrogenase deficiency. However, its use may increase given current shortages of indigo carmine (American Urogynecologic Society, 2014a).

Cystoscopy

The anterior urethral wall is sensitive, and discomfort may result if the sheath’s tapered edge is directed anteriorly. Thus, the sheath is inserted into the urethral meatus with the bevel directed posteriorly. Immediately following insertion into the external urethral opening, medium flow is begun.

The cystoscope is advanced toward the bladder under direct visualization. Often, in women with anterior wall prolapse, the urethra slopes downward, and the scope tip is similarly directed. During the procedure, the cystoscope can be steadied with one hand holding the sheath near the urethral meatus (Fig. 45-1.2).

Bladder Inspection

Upon entry into the bladder, the cystoscope is slowly withdrawn until the bladder neck is identified. The cystoscope is then advanced and rotated 180 degrees so that the light-source cable is pointing down. In this position, an air bubble is noted at the dome, which provides orientation for the remainder of the cystoscopic examination. When a 70- or 30-degree scope is used, the cystoscope is angled upward to view this bubble. To maintain orientation during rotation, the camera is held static while the light cord and cystoscope are rotated (Fig. 45-1.3).

As the distended bladder assumes a spherical shape, it is systematically inspected on each side from apex to internal urethral opening. First, to view the entire left side of the bladder, the cystoscope and light cable are rotated approximately 90 degrees in a clockwise fashion. The surgeon’s left hand is used to prevent awkward hand crossing. To examine the bladder wall from 12 to 3 o’clock positions, the cystoscope is initially angled upward and then pans down to the 3 o’clock position, at which point the scope is parallel to the floor. Next, inspection from 3 to 6 o’clock requires gradual downward angling of the cystoscope. The left ureteral orifice is generally found at the 5 o’clock position, approximately 3 to 4 cm proximal to the internal urethral opening. During bladder inspection, especially the base or posterior wall, digital elevation of the anterior vaginal wall to lift the bladder floor and orifices to a more anatomically correct position is beneficial if pelvic organ prolapse is present. Moreover, accentuated angling may be needed. Once the left orifice is noted, further subtle clockwise rotation of the cystoscope along the interureteric ridge permits isolation of the right ureteral orifice.

The cystoscope is again rotated so that the light-source cable is again pointing downward and the bubble at the dome is again identified. For the right side, counterclockwise movement of the cystoscope and light cord with the surgeon’s right hand averts awkward hand crossing. The right wall of the bladder is then similarly examined.

While horizontal to the floor, the cystoscope is withdrawn to the bladder neck and then angled downward to provide a second view of the trigone and both ureteral orifices and to document ureteral patency. Brisk urine flow, with or without indigo carmine, should be seen from each orifice. Peristalsis of the ureteral orifice alone, without flow, is insufficient to document patency. Moreover, scant flow may indicate partial ureteral obstruction and merits further evaluation.

The average time to efflux approximates 10 minutes but can be longer. After 20 minutes, absent jets bilaterally more often reflect hypovolemia and resolve with fluid bolus. Following this bolus, 10 to 20 mg of furosemide (Lasix) can be added as needed to promote diuresis. Underlying renal disease may also delay efflux. During inspection, a unilateral jet is more concerning for ureteral injury. To evaluate, the surgeon can attempt to thread a stent through the ureteral orifice and into the ureter, as described in Step 8. Repair of ureteral injury is described in Chapter 40.

Operative Cystoscopy

For this procedure, the operative instrument (biopsy or grasping forceps or scissors) is introduced through the operating port, until viewed at the end of the cystoscope. Prior to instrument insertion, a rubber adapter cap is positioned over the operating port to create a watertight seal with the operative instrument. Once in view, the instrument and cystoscope are moved together as a unit toward the area of interest.

Ureteral Stenting

Ureteral stents may be placed at several junctures during surgery. They may be inserted at the beginning of surgery and left through its duration to define anatomy in cases in which the ureter is at high surgical risk of injury. Alternatively, they may be threaded intraoperatively to document ureteral patency and exclude injury. Finally, ureteral stents may be positioned and left in place at the conclusion of surgery if ureteral injury is suspected or identified. Duration of postoperative stenting is variable and based on indications.

Ureteral stents are available in various sizes, and those ranging from 4 to 7 F are commonly used. Stents vary in length from 20 to 30 cm, and a 24-cm length is appropriate for most adults. Generally, open-ended or whistle-tip stents are used to delineate anatomy or to exclude obstruction. Double- or single-pigtail stents are used in situations that require prolonged ureteral drainage.

To Exclude Ureteral Obstruction

A 4F to 6F open-ended or whistle-tip stent is threaded through the operating channel of a 30-degree cystoscope and into the field of view. By advancing both the stent and cystoscope toward the orifice, the stent is passed into the ureteral orifice. After the stent has entered the opening, it is manually threaded and advanced. Alternatively, an Albarrán bridge may be used. This specialized bridging sheath allows deflection and guidance of a stent into an orifice.

Once inserted, a stent is advanced past the level of suspected obstruction. If a stent threads easily, obstruction is excluded. In most gynecologic surgery, this would not be higher than the pelvic brim, which should be 12 to 15 cm from the ureteral orifice in adults. When passing a stent, undue pressure is avoided during advancement to avoid ureteral perforation. Efflux should be documented after stent removal.

If ureteral transection or stricture is suspected from the above steps, a cone-tip ureteral catheter is inserted, and dye is injected into the distal ureter to locate extravasation or point of narrowing. This is done intraoperatively with fluoroscopic guidance. If dye flows to the renal pelvis easily and no extravasation noted, ureteral injury is unlikely.

If gross blood issues from an orifice prior to ureteral manipulation, the ureter may be partially transected. Even if good efflux is noted, many insert and maintain a double-J stent for approximately 4 weeks. In such cases, a computed tomography (CT) urogram or renal sonogram is completed 4 to 12 weeks after stent removal to exclude stricture.

After the above interrogations, absent efflux from one orifice may uncommonly reflect a long-standing unilateral nonfunctioning kidney. For this, postoperative CT and nuclear scan can be selected.

To Delineate Anatomy

For this purpose, the stent is advanced until resistance is met, which indicates that the renal pelvis has been reached. The stent is tied securely to the transurethral catheter and drains into the cystoscopy drape. At the conclusion of surgery, the stent is removed.

Ureteral Stenting

In cases in which a ureteral stent is required postoperatively, a double-pigtail stent is used. The proximal coil of the stent prevents renal pelvis injury, and the distal coil secures placement in the bladder.

For placement, a guide wire is first threaded into the ureteral orifice and passed to the renal pelvis. The pigtail stent is then placed over the guide wire and advanced by a pusher device until the distal end enters the bladder. The guide wire is removed, allowing the ends to coil in the renal pelvis and bladder, respectively. Correct upper coil positioning is confirmed intraoperatively using fluoroscopy or plain film radiograph. Stents are usually kept for 2 to 8 weeks depending on the injury identified or suspected. They are generally removed in the office with cystoscopic guidance.

Biopsy and Foreign Body Removal

Mucosal lesions can be biopsied with minimal risk or discomfort to the patient. A biopsy instrument is introduced into the cystoscope’s operating port and brought into the operative field. With the instrument in view, the cystoscope is moved directly to the lesion. Biopsy is performed, and the cystoscope and instrument are withdrawn through the urethra together. In this way, a biopsy specimen is not pulled through the sheath and possibly lost. Bleeding is usually minor and will stop by itself. For brisk bleeding, electrosurgical coagulation can be used if a nonconducting solution was selected as the distention medium. As described in Chapter 41, electrolyte solutions such as saline cannot be used with monopolar electrosurgery. These solutions conduct current, thus dissipating the energy and thereby rendering the instrument useless.

Foreign bodies, such as stones, are removed using the same technique as biopsy. The instrument is used to grasp the foreign body and then removed together with the cystoscope.

Suprapubic Teloscopy

This is a technique used to visualize the bladder through an abdominal approach. We have found suprapubic teloscopy to be valuable when the ureters must be assessed during a difficult cesarean delivery or during a laparotomy in which a woman has not been positioned to allow easy cystoscopic access to the urethra.

The bladder is distended using the transurethral Foley catheter until the bladder wall is tense. A wide purse-string using 2-0 gauge absorbable suture is then placed at the bladder dome, taking deep bites into the bladder muscularis (Fig. 45-1.4). The two suture ends are elevated but held loosely. A small stab incision is then made in the purse-string’s center, and a cystoscope is introduced into the bladder. This incision is preferably made in the retropubic or extraperitoneal portion of the bladder dome to minimize risk of fistula formation. For suprapubic teloscopy, a 30-degree cystoscope is most effective. The two suture ends are then pulled up and held tightly to prevent the escape of distending fluid. To allow visualization of the trigone and ureteral orifices, the Foley bulb is deflated but left in place. Indigo carmine or methylene blue is given if necessary to document ureteral efflux. If the ureteral orifices still cannot be visualized, the bladder incision is extended inferiorly into the retropubic portion to allow direct visualization. At the conclusion of teloscopy, the cystoscope is removed, and the purse-string suture is tied, closing the cystotomy.

POSTOPERATIVE

Office cystoscopy does not require specific postoperative management except for prophylactic antibiotics to cover common urinary tract pathogens. At our institution, we prescribe a single perioperative dose. With operative cystoscopy, hematuria may develop, but it generally clears within a few days and is considered significant only if associated with symptomatic anemia. With long-term ureteral stenting, additional complications may include ureteral spasm, which typically presents as back pain. Stone formation and stent fragmentation are less common but can occur if length of catheterization exceeds 8 weeks.

Abdominal antiincontinence procedures at­tempt to correct stress urinary incontinence (SUI) by stabilizing the anterior vaginal wall and urethrovesical junction in a retropubic location. Specifically, the Burch procedure, also known as retropubic urethropexy, uses the strength of the iliopectineal ligament (Cooper ligament) to stabilize the anterior vaginal wall and anchor the wall to the musculoskeletal framework of the pelvis (Fig. 38-24).

The Burch colposuspension is usually performed through a Pfannenstiel or Cherney incision. In the past 20 years, some have introduced laparoscopic approaches that use suture or mesh to affix the paravaginal tissues to Cooper ligament (Ankardal, 2004; Zullo, 2004). Compared with open Burch colposuspension, laparoscopic approaches offer similar postoperative rates of subjective cure, despite some evidence for poorer objective outcomes (Carey, 2006; Dean, 2006). Longer-term results will also define its role.

PREOPERATIVE

Patient Evaluation

Prior to surgery, patients undergo complete urogynecologic evaluation. Although not required for uncomplicated demonstrable SUI, urodynamic testing can help differentiate stress and urgency incontinence and assess bladder capacity and voiding patterns (Chap. 23).

Many women with SUI may also have associated pelvic organ prolapse. For this reason, other indicated pelvic reconstructive surgeries commonly accompany Burch colposuspension. A required hysterectomy does not appear to improve or worsen Burch procedure success rates (Bai, 2004; Meltomaa, 2001).

Consent

For most women with SUI, Burch colposuspension offers a safe, effective long-term treatment for incontinence. In one systematic review, overall continence rates ranged from 85 to 90 percent at 1 year and declined to 70 percent by 5 years (Lapitan, 2012). Surgical risks compare similarly with other surgeries for SUI (Green, 2005; Lapitan, 2003). Intraoperative complications are rare and may include ureteral injury, bladder or urethral perforation, and hemorrhage (Galloway, 1987; Ladwig, 2004).

Complications following surgery, however, are not uncommon and may include urinary tract or wound infection, voiding dysfunction, de novo urinary urgency, and pelvic organ prolapse—primarily enterocele formation (Alcalay, 1995; Demirci, 2000, 2001; Norton, 2006). Overcorrection of the urethrovesical angle has been suggested as a cause of these long-term urinary and prolapse complications.

Patient Preparation

The American College of Obstetricians and Gynecologists (2014) recommends antibiotic prophylaxis prior to urogynecologic surgery, and appropriate choices mirror those for hysterectomy (Table 39-6). For all patients undergoing major gynecologic surgery, thromboprophylaxis is also recommended (Table 39-8). Bowel preparation is based on surgeon preference and on concurrent surgeries planned.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

Burch colposuspension may be performed under general or regional anesthesia as an inpatient procedure. The patient is placed supine with legs in booted support stirrups in low lithotomy position. The abdomen and vagina are surgically prepared, and a Foley catheter is inserted.

Abdominal Incision

A low Pfannenstiel or Cherney incision is performed (Section 43-2). Surgery in the space of Retzius (retropubic space) is easier to accomplish if the incision is placed low on the abdomen, approximately 1 cm above the upper border of the pubic symphysis. If hysterectomy, culdoplasty, or other intraperitoneal procedure is planned, the peritoneum is entered and concurrent surgery completed prior to colposuspension. If the procedure is done in isolation, fascia of the anterior abdominal wall muscles and then transversalis fascia are incised, but entry into the peritoneal cavity is not required to reach the retropubic space.

Entry into the Space of Retzius

Between the lower anterior abdominal wall peritoneum and pubic bone lies an avascular plane, that is, the space of Retzius. To enter this retropubic space, the fingers of one hand gently dissect along the cephalad surface of the pubic bone. Alternatively, gentle sponge dissection can be used to open this space (Fig. 45-2.1). Loose areolar tissue is found behind the symphysis within this space and easily separates from the bone. However, entry into the wrong tissue plane risks bleeding and bladder injury. Direct exposure of the back of the pubic bone ensures that the correct space has been entered. The bladder and urethra are gently pulled downward and away from the pubic bone, and the space of Retzius opens.

In those with prior surgery, sharp dissection is generally required. Dissection begins with the curved tips of Metzenbaum scissors placed directly on the pubic bone and progresses dorsally until the space is exposed. Sutures can be used to control bleeding from torn paravaginal vessels.

During space of Retzius dissection, the obturator canal is identified early to avoid neurovascular injury to the obturator vessels and nerves. The canal is typically found 1.5 to 2.5 cm below the upper border of the iliopectineal ligament and approximately 5 to 7 cm from the midline of the upper border of the symphysis pubis (Drewes, 2005). Accessory obturator vessels that commonly pass over Cooper ligament to enter the obturator canal are also identified. These can be lacerated during pronounced retraction to expose Cooper ligament.

Exposing the Anterior Vaginal Wall

After opening this space, fingers of the surgeon’s nondominant hand are placed intravaginally at the vagina’s midlength and just behind the pubic bone. With one on each side, the finger pads straddle the urethra and push the vagina ventrally. Working within the retropubic space and beginning at the lateral borders of the urethra, gentle downward and lateral pressure against the finger pad bluntly dissects away fat. This exposes the pearly white periurethral tissue between the arcus tendineus fascia pelvis (ATFP), which lies laterally, and urethra, which is medial. If necessary, a surgeon can use a Kittner (peanut) sponge or gauze sponge stick. Importantly, to protect the delicate urethral musculature, this dissection remains lateral to the urethra.

Aggressive dissection or Burch sutures may lacerate vessels within the Santorini plexus of paravaginal veins and risk significant bleeding (Fig. 38-24). This is easily controlled with upward pressure from the vaginal fingers. Identified vessels can then be ligated.

Urethrovesical Junction

Identifying this site aids correct suture placement. To isolate the urethrovesical junction, the surgeon’s vaginal hand positions the Foley catheter balloon at the bladder neck. Undue tension on the Foley catheter is avoided as this can drag the bladder into the operative field and increase the risk of sutures entering the bladder.

Suture Placement

For exposure, the surgeon’s vaginal finger presses upward, and the bladder neck is gently displaced by an assistant to the contralateral side by a narrow retractor. To suspend tissue, a double-armed suture of 2-0 gauge nonabsorbable material is placed laterally on each side of the urethra. A first suture is placed 1.5 to 2 cm lateral to the proximal third of the urethra. The needle point is directed toward the vaginal finger, and a thimble may be used to avoid needle-stick injury. For this suturing, a figure-of-eight stitch is used and incorporates vaginal wall while excluding epithelium. A second suture is then placed 1.5 to 2 cm lateral to the urethrovesical junction. Identical sutures are placed on the opposite side of the urethra (Fig. 45-2.2).

Both ends of each suture are then placed through the nearest point of the ipsilateral iliopectineal ligament. Slack is removed from each suture, and knots are tied above the ligament. With knot securing, suture bridges are expected, and these should stabilize but not elevate the anterior vaginal wall and urethrovesical junction. The vaginal wall is stabilized approximately at the level of the distal portion of the ATFP and not significantly higher. Greater elevation of the bladder neck risks postoperative voiding dysfunction.

Cystoscopy

Following suture ligation, cystoscopy is performed. This allows identification and removal of any errant sutures that may traverse the bladder or urethral mucosa. Moreover, it enables a surgeon to inspect the ureteral orifices and document efflux.

Catheterization

After colposuspension, the Foley catheter may remain to drain the bladder. Alternatively, a suprapubic catheter may be placed. Investigators comparing the two have found no differences in antiincontinence procedure success rates, length of hospitalization, or rates of infection. Urethral catheterization, however, was linked with a shorter duration of catheterization but also greater patient discomfort (Dunn, 2005; Theofrastous, 2002).

Incision Closure

The anterior abdominal wall peritoneum is generally closed to prevent displacement of small bowel into the retropubic space. The remaining abdominal wall incision is closed as described in Section 43-2.

POSTOPERATIVE

In general, recovery follows that associated with laparotomy and varies depending on concurrent surgeries and incision size. A voiding trial as described in Chapter 42 (is performed prior to hospital discharge.

The tension-free vaginal tape procedure (TVT) is the most commonly performed operation worldwide for stress urinary incontinence. The procedure is one of the most widely studied incontinence operations, and cure rates up to 17 years approximate 80 percent (Holmgren, 2005; Nilsson, 2013; Song, 2009). The TVT procedure has also become the prototype for a host of other incontinence operations, which include the TOT (transobturator tape), TVT-O (tension-free vaginal tape obturator), and single-incision midurethral slings (“mini-slings”). These are all considered midurethral slings (MUS) and are based on the concept that midurethral support is vital to continence.

Tension-free vaginal tape placement is indicated for SUI that is secondary to urethral hypermobility or intrinsic sphincteric deficiency (Chap. 23). It is used for primary cases and for women who have had prior antiincontinence procedures.

During TVT, a permanent sling material is placed underneath the midurethra, traverses the periurethral tissue, passes behind the pubic bone through the space of Retzius, and exits through the anterior abdominal wall. Once positioned, tissue ingrowth ultimately holds the mesh in place. During placement, the TVT needle is directed blindly through the space of Retzius and can lacerate vessels there to create significant bleeding. A modification of the TVT, the TOT was developed to avoid hemorrhage in this space and to decrease bladder and bowel perforation risks. However, the TVT remains the primary standard operation for SUI.

The TVT device consists of a permanent polypropylene mesh covered with a plastic sheath that is removed after the mesh is positioned. The plastic sheath is believed to prevent bacterial contamination of the mesh as it passes through the vagina and to protect the mesh from being damaged during passage. Once these plastic sheaths are removed, the mesh remains fixed in position. The mesh is attached to two metal disposable needles that are connected to a reusable metal introducer during placement. A metal catheter guide is used to displace the urethra away from the needle during the procedure.

PREOPERATIVE

Patient Evaluation

Prior to TVT procedures, a diagnosis of SUI must be made as described in Chapter 23. Importantly, in some women, SUI can be occult and masked by pelvic organ prolapse that kinks and partially obstructs the urethra. Accordingly, prolapse replacement to reestablish more normal anatomy during urodynamic testing may help unmask this potential SUI. Also of note, caution is exercised in patients who are Valsalva voiders. These women void with abdominal straining rather than with detrusor contraction and urethral relaxation. Most incontinence procedures prevent leakage by closing the urethra during cough or Valsalva maneuver. Therefore, these surgeries, when performed in women who rely on the Valsalva maneuver to urinate, will often result in voiding dysfunction. This tenet applies to all midurethral sling procedures.

Consent

The consenting process for TVT should include an honest discussion of outcomes. At best, the 5-year cure rate is 85 percent, with another 10 percent significantly improved. However, some patients will develop postoperative urgency incontinence, and others will develop bothersome voiding dysfunction. Additionally, with time and aging, incontinence may recur secondary to factors not related to urethral support.

As for all antiincontinence procedures, prior to surgery, the patient is provided surgical success rates from the literature and those of the individual surgeon. Moreover, the definition of “outcome success” varies from woman to woman. For example, in a patient with severe incontinence and 20 leakage episodes per day, improvement to one leakage episode every other day would be considered successful. However, in a woman with rare leakage, it may be more difficult to achieve an outcome considered satisfactory. Therefore, patient’s expectations are discussed prior to surgery.

The short-term complications of the TVT procedure include incomplete bladder emptying requiring drainage with Foley catheter or intermittent self-catheterization for several days. A small percentage of patients will develop long-term urinary retention requiring reoperation for tape division or excision. In these women, continence rates decrease. The TVT procedure is associated with a learning curve, and urinary retention rates decline as the number of cases a physician performs accrues. Postoperatively, vaginal mesh erosion may develop as an early or late complication. This is managed by simple excision of the piece of eroding tape and vaginal wall revision. Of note, the American Urogynecologic Society (2014b) considers the mesh used for this sling to be safe and effective.

Intraoperative complications include hemorrhage, bladder perforation, and rarely, bowel injury. Major vessels are injured in less than 1 percent of cases.

Patient Preparation

The American College of Obstetricians and Gynecologists (2014) recommends antibiotic prophylaxis prior to urogynecologic procedures, and appropriate choices mirror those for hysterectomy (Table 39-6). For all patients undergoing major gynecologic surgery, thromboprophylaxis is recommended (Table 39-8). Bowel preparation is based on surgeon preference and mainly on concurrent surgeries planned.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

The procedure was initially described as an ambulatory surgical procedure performed under local anesthesia. However, it can also be performed with regional or general anesthesia. If performed solely, TVT in most cases is a day-surgery operation. The procedure is performed in standard lithotomy position. The vagina is surgically prepared, and an 18F Foley catheter, which allows passage of a rigid catheter guide, is inserted to assist in deflection of the urethra during needle passage.

Abdominal Incisions

To begin, two ½-cm skin incisions are made at the level of the upper border of the symphysis, and each lies no further than 2 cm from the midline. More lateral placement risks ilioinguinal nerve injury (Geis, 2002).

Vaginal Incisions

A midline incision is made sharply in the vaginal epithelium and superficial vaginal muscularis beginning 1 cm proximal to the external urethral opening and is extended 1.5 to 2 cm cephalad. Allis clamps are placed on the edges of the vaginal incision for traction. Using Metzenbaum scissors, bilateral periurethral tunnels are created beneath the vaginal epithelium on either side of the urethra. These tunnels extend several centimeters toward the inferior pubic rami to allow placement of the TVT needle just behind the pubic bone.

Catheter-guide Placement

A rigid guide is placed through the 18F Foley catheter. During passage of TVT needles, a surgical assistant uses the catheter guide to deflect the urethra to the contralateral side to lower urethral injury risks.

Mesh Placement

The TVT needle and mesh are attached to the introducer. The needle is placed through one of the periurethral tunnels so that its point touches the front surface of the ipsilateral pubic ramus (Fig. 45-3.1). A hand placed in the vagina then carefully guides the needle around the back of the ramus. The needle is then curved upward toward the ipsilateral abdominal incision, perforates the periurethral tissue just behind the pubic bone, and enters the retropubic space (Rahn, 2006). During this, the needle is always directly behind the pubic bone. Pressure is applied to the introducer handle with the other hand, but the vaginal hand controls the needle’s direction. The handle of the introducer always remains parallel to the ground to avoid lateral excursion into major vessels and obturator nerve (Fig. 45-3.2). Additionally, after the needle passes around the pubic ramus and behind the symphysis, its tip is always directed toward the abdominal wall incisions. The bladder may be perforated if excessive pressure is applied and if the needle is aimed cephalad rather than toward the abdominal wall (Fig. 45-3.3). Small changes in the position of the hand applying handle pressure can lead to bladder perforation.

Cystourethroscopy

After the needle perforates the abdominal wall, the Foley and catheter guide are removed, and cystourethroscopy is performed with a 70-degree cystoscope. The bladder is distended with 200 to 300 mL of fluid, and inspection for cystotomy is completed. Generally, perforation will be obvious, and the TVT needle will be seen entering and exiting the bladder. In this situation, the needle is removed and redirected, and correct placement is confirmed by cystoscopy. Inspection of the urethra is also essential and can be performed with the same 70-degree angle scope. Alternatively, a 0-degree or 30-degree endoscope may be used. Iatrogenic trocar bladder injury, if identified intraoperatively does not appear to influence continence outcomes or increase postoperative voiding dysfunction or infection rates (Zyczynski, 2014).

In contrast to bladder perforation, urethral perforation theoretically carries a risk of urethrovaginal fistula. Thus, if urethral perforation is noted, most surgeons abort the procedure and postpone until several months later.

After cystoscopy, the introducer is unscrewed from the needle. The needle is brought through the abdominal wall. The needle is then cut from the mesh, and the mesh is held with a hemostat. Next, the other TVT needle is attached to the introducer and is placed on the other side of the urethra in a similar fashion. Cystourethroscopy is then repeated.

Setting Mesh Position

A hemostat or similar instrument is placed between the suburethral tissue and the tape to act as a spacer and create distance between the mesh and urethra (Fig. 45-3.4). This spacing avoids excessive mesh tension and lowers the risk for postoperative urinary retention and voiding dysfunction. Prior to sheath removal, the vaginal sulci are inspected to exclude perforation of the vaginal epithelium occurring during needle guidance. If perforated mesh is seen, the tape is removed, and the TVT needle is again passed through a newly created periurethral tunnel that lies slightly medial to the original. The vaginal perforation defect is repaired with one or two simple interrupted delayed-absorbable sutures.

Sheath Removal

Once the tape is satisfactorily positioned, an assistant then removes the plastic covering around the mesh, while the surgeon holds the mesh at the desired distance from the urethra using the spacer instrument. The plastic covering is lifted away from both sides with minimal tension to avoid mesh stretching or undue urethral elevation. With ideal positioning, a few millimeters of free space separate the suburethral tissue and mesh. The mesh is trimmed just below the skin at the abdominal incisions (Fig. 45-3.5).

Wound Closure

The vaginal incision is closed in a running fashion with 2-0 gauge delayed-absorbable suture. The abdominal incisions may be closed with Dermabond or with a single interrupted 4-0 gauge delayed-absorbable skin suture.

POSTOPERATIVE

Prior to discharge from a day-surgery unit, an active voiding trial is performed (Chap. 42). If the patient fails this trial, a Foley catheter is replaced and kept for 1 to 3 days prior to a second voiding trial. Alternatively, a patient can be taught self-catheterization. This is continued until postvoid residual volumes fall below about 100 mL.

Normal diet and activity can resume during the first postoperative days. Intercourse, however, is postponed until the vaginal incision is healed, usually at 6 weeks. The time to resumption of exercise and strenuous physical activity is controversial. A standard recommendation has been to delay these at least 2 months, although there are no data supporting this. However, logic would suggest that this is reasonable for adequate healing.

The transobturator tape (TOT) sling procedure is a variation of the midurethral sling procedures, which began with tension-free vaginal tape (TVT). With the TOT procedure, a permanent sling material is inserted bilaterally through the obturator foramen and extends underneath the midurethra. As a result, the space of Retzius is avoided and thereby minimizes the potential for associated bladder and bowel injuries. Bleeding in the space of Retzius is a primary TVT complication, and avoiding this space is an attractive TOT feature. Additionally, in patients who have had prior incontinence procedures and have scarring in the space of Retzius, bladder perforation may be averted by avoiding dissection in this space.

The procedure has several important differences from TVT, and there are also several modifications of the TOT procedure itself. Several companies produce kits containing required mesh and placement needles for TOT. The two major types of TOT procedures are defined by whether needle placement begins inside the vagina and is directed outward, termed an in-to-out approach, or starts outside the vagina and is directed inward, called an out-to-in approach. Limited data do not show superiority of one over the other (Debodinance, 2007). Currently, the out-to-in technique is more commonly performed and is described here.

Generally, TOT is indicated for primary SUI secondary to urethral hypermobility (Chap. 23). In patients with SUI secondary to intrinsic sphincteric deficiency, the value of TOT is unclear, as results are conflicting and data are limited (Rechberger, 2009; Richter, 2010).

PREOPERATIVE

Patient Evaluation

Evaluation and preparation prior to TOT mirrors that for TVT.

Consent

As with other surgeries for incontinence, the major risks of this procedure are voiding dysfunction, urinary retention, development of urgency incontinence, and failure to correct SUI. Groin and thigh pain appear to be another potential postoperative problem. Long-term complications may be associated with the supporting mesh and include mesh erosion (Schimpf, 2014).

Intraoperatively, there is some risk of bladder or urethral perforation, although this is believed to be significantly less than that with TVT. Inappropriate TOT trocar placement rarely can lead to significant hemorrhage or neurologic deficits if obturator nerve and vessel branches are damaged in the thigh compartment.

INTRAOPERATIVE

Instruments

A TOT kit will contain two TOT needles and synthetic mesh tape. The TOT needle is designed to navigate the path from the entry point around the pubic rami to the midurethral vaginal wall incision. A plastic sheath surrounds the mesh tape and allows the mesh to be pulled into position smoothly. However, once these plastic sheaths are removed, the mesh remains fixed in position.

Surgical Steps

Anesthesia and Patient Positioning

If performed solely, a TOT procedure in most cases is a day-surgery procedure. It is performed in standard lithotomy position under general, regional, or local anesthesia. The vagina is surgically prepared, and a Foley catheter is placed to assist in determination of urethral location.

Vaginal Incisions

A midline incision is made sharply in the vaginal epithelium and superficial muscular layer beginning 1 cm proximal to the external urethral opening and is extended 2 to 3 cm cephalad. Allis clamps are placed on the edges of the vaginal incision for traction. Using Metzenbaum scissors and blunt finger dissection, bilateral periurethral tunnels are created beneath the vaginal epithelium on either side of the urethra. These tunnels extend up to and behind the ischiopubic rami.

Thigh Incisions

A 0.5- to 1-cm entry incision is made bilaterally in the thigh-crease skin (genitocrural fold), 4 to 6 cm lateral to the clitoris, and at the point where the adductor longus insertion can be palpated. This muscle arises from the superior ramus of the pubis and inserts medially at the midlength of the femur.To summarize the needle's path, insertion starts along the lateral edge of the ischiopubic ramus just below the insertion of the adductor longus tendon and arches around the ramus. During this arc, the needle sequentially penetrates the gracilis, adductor brevis, and obturator externus muscles, obturator membrane, obturator internus muscle, and periurethral endopelvic fascia and exits through the vaginal incision.

Mesh Placement

The TOT needle is grasped, and the tip is placed in one of the thigh incisions (Fig. 45-4.1). The tip is directed cephalad until the obturator membrane is perforated, and a “popping” sensation is felt. A vaginal finger is placed in the ipsilateral vaginal tunnel and is positioned up to and behind the ischiopubic ramus. Using the curve of the TOT needle, the surgeon then directs the needle tip to the end of his finger and passes the needle into the vagina (Fig. 45-4.2). At this time, the vaginal sulcus is inspected to exclude perforation. If the needle has perforated the sulcus epithelium, it is removed and reinserted correctly. Next, the TOT covered mesh is attached to the needle end, and the needle retraces its original path as it is withdrawn back through the thigh incision. With this, the covered mesh is threaded into position. The mesh is then removed from the needle. The procedure is repeated on the other side (Fig. 45-4.3).

Setting Mesh Position

A hemostat or similar instrument is placed and opened between the urethra and mesh to act as a spacer and create distance between the mesh and the urethra (Fig. 45-4.4). This spacing avoids excessive urethral elevation and lowers postoperative urinary retention risks. Prior to sheath removal, the vaginal sulci are again inspected to exclude perforation. If mesh is seen in a sulcus, the tape is removed and reinserted on the affected side.

Sheath Removal

An assistant surgeon then removes the plastic covering of the mesh from each of the thigh incisions. Concurrently, the surgeon holds the mesh at the desired distance from the urethra using the spacer instrument. The plastic covering is removed with minimal tension to avoid mesh stretching. The mesh is trimmed just inside thigh incisions.

Wound Closure

The vaginal incision is closed in a running fashion with 2-0 gauge delayed-absorbable suture. The thigh incisions may be closed with a single interrupted subcuticular suture with 4-0 gauge delayed-absorbable suture or with other suitable skin closure methods (Chap. 40).

Cystourethroscopy

The procedure is marketed as one in which cystoscopy is not necessary. However, because the bladder and urethra can be injured, we recommend postprocedural cystoscopy.

POSTOPERATIVE

Prior to discharge from a day-surgery unit, an active voiding trial is performed (Chap. 42). If significant residuals persist, a Foley catheter remains. A second voiding trial can be repeated in a few days or at the surgeon’s discretion. Alternatively, a patient can be taught self-catheterization. This is continued until postvoid residuals fall below approximately 100 mL.

Normal diet and activity can resume during the first postoperative days. Intercourse, however, is delayed until the vaginal incision is healed. The time to resumption of exercise and strenuous physical activity is controversial. A standard recommendation delays these at least 2 months. Data to support this are lacking, however, logic would suggest that this is reasonable to allow adequate healing.

Pubovaginal sling is a standard procedure for SUI. It has traditionally been used for SUI stemming from intrinsic sphincteric deficiency (Chap. 23). In addition, this procedure may also aid patients with prior failed antiincontinence operations. It is generally not employed in a woman having her first surgery for incontinence.

In the past, different materials had been used for the sling, however, autologous fascia is currently preferred. Generally, this fascia is obtained from the patient’s rectus sheath, although fascia lata from the thigh may alternatively be harvested. With this surgery, a strip of fascia is placed at the proximal urethra through the space of Retzius, and ends are secured either to each other or to the rectus fascia above the rectus abdominis muscle.

In contrast to midurethral slings, which generally employ premade kits and standardized procedural steps, the technical aspects of autologous fascia pubovaginal slings have greater variability. These include size and location of harvested tissue, anchoring method of the sling to the rectus fascia, and technique for determining mesh tension across the proximal urethra. Steps for the rectus fascial sling are described here.

PREOPERATIVE

Patient Evaluation

As with other antiincontinence procedures, patients require urogynecologic evaluation, including urodynamic testing to confirm SUI and intrinsic sphincteric deficiency. Additionally, SUI often accompanies pelvic organ prolapse. Thus, the need for concurrent repair of associated prolapse is assessed prior to surgery (Chap. 24).

Consent

In addition to general surgical risks, patients are counseled regarding the risk of recurrent incontinence, urinary retention, and voiding dysfunction following surgery (Albo, 2007). Overall, traditional slings seem to be as effective as minimally invasive slings but have higher rates of adverse effects (Rehman, 2011).

Patient Preparation

Antibiotics and thromboprophylaxis are given as outlined in Tables 39-6 and 39-8.

Bowel preparation is based on surgeon preference and mainly on concurrent surgeries planned.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

Pubovaginal sling may be performed under general or regional anesthesia as an inpatient procedure. The patient is placed in standard lithotomy position, with lower extremities positioned in candy-cane or booted support stirrups. The abdomen and vagina are surgically prepared, and a Foley catheter is inserted.

Graft Harvest

A transverse skin incision is made 2 to 4 cm above the symphysis and is large enough to allow removal of a transverse fascial strip that measures, at minimum, 1.5 cm wide × 6 cm long. The incision is carried down through subcutaneous tissue to the fascia.

The fascia to be harvested is outlined and then incised, sharply dissected away from the underlying rectus muscle bellies, and removed. Following removal, the strip is cleaned of fat and adventitial tissue. A helical stitch using 0-gauge polypropylene suture is then placed through the fascia at each end of the strip. This stitch is repeated at the other end. These sutures are not tied. The fascial incision is then closed in a running fashion with 0-gauge delayed-absorbable suture.

Vaginal Incision

At a point 2 cm proximal to the external urethral orifice, a 3- to 5-cm midline vertical incision is made sharply in the anterior vaginal wall and extended cephalad. Alternatively, a U-shaped incision is made at the level of the bladder neck. Sharp and blunt dissection is used to separate the vaginal epithelium from the underlying fibromuscular layer. The space of Retzius is then entered with a combination of sharp and blunt dissection bilaterally by penetrating the periurethral connective tissue (Fig. 45-5.1). Entry into this space is confirmed by the surgeon’s finger palpating the dorsal surface of the pubic bone (Fig. 45-5.2). During entry, Santorini’s venous plexus can be lacerated, and bleeding is controlled with compression or stitches of 2-0 gauge absorbable suture.

Fascia Placement

A 0.5- to 1-cm long fascial incision is made no further than 2 cm from the midline on each side. These are placed caudal to the prior harvest incision and just above the pubic bones. A long dressing or packing forceps or needle ligature carrier is placed into one of these incisions and from above, perforates the rectus tendon. The instrument is placed against the back of the pubic bone and advanced toward the vagina. Concurrently, the surgeon guides the instrument to his finger within the space of Retzius and advances it into and through the vaginal incision (Fig. 45-5.3). At this time, cystourethroscopy is performed to exclude bladder or urethral perforation.

The suture ties at one end of the fascial strip are grasped with the perforating forceps and threaded up through the abdominal incision on one side of the urethra. With the other end of the sling, this step is repeated on the other side of the urethra. As a result, the fascial sling lies positioned below the bladder neck (Fig. 45-5.4). Usually four 2-0 gauge delayed-absorbable sutures may be used to fix the proximal and distal edges of the sling beneath the bladder neck to prevent displacement during sling positioning. Stitches are placed lateral to the urethra.

Setting Sling Position

Within the laparotomy incision, sutures attached to the sling ends from each side meet and are tied together above the rectus sheath. During knot tying, a space of two to three fingerbreadths is left between the knot and fascia to prevent bladder neck obstruction and urinary retention. In addition, a hemostat is placed between the suburethral tissue and the fascial sling to create distance between the sling and urethra (see Fig. 45-4.4). After the knot is secured, there should be no upward angulation of the urethra or bladder neck, and a few millimeters of free space should be noted between the fascial sling and the bladder neck.

Cystourethroscopy

Cystoscopy is again performed to exclude bladder or urethral perforation. In addition, excessive resistance noted during passage of the cystoscope into the bladder may suggest undue sling tension, which can lead to postoperative obstructive symptoms. If such resistance is noted, the sling is loosened.

Vaginal Incision

The vaginal incision is closed with 2-0 gauge delayed-absorbable suture in a running fashion. A Foley catheter is left in place. In the past, suprapubic tube insertion was common practice. However, with a trend toward tying the fascial sling with less tension, the risk of prolonged urinary retention is lowered, and suprapubic drainage is therefore not typically required.

Abdominal Incision

The two prior 1-cm fascial incisions are closed with an interrupted stitch of delayed-absorbable suture. The remaining abdominal incision is closed as described in Section 43-2.

POSTOPERATIVE

In general, recovery follows that associated with laparotomy and is heavily dependent on incision size. A voiding trial as described in Chapter 42 is performed prior to hospital discharge.

Injection of bulking agents into the urethral submucosa is one method available to treat SUI that results from intrinsic sphincter deficiency (ISD) (Chap. 23). Although mechanisms are not completely clear, effectiveness may result from expansion of the urethral walls, which allows them to better approximate or coapt. As a result, intraluminal resistance to flow is increased and continence is restored. Alternatively, injections elongate the functional urethra, and this may allow more even distribution of abdominal pressures across the proximal urethra to resist opening during stress (Monga, 1997).

Although traditionally recommended for treatment of SUI solely due to ISD, some evidence suggests it can be used to treat SUI resulting from combined ISD and urethral hypermobility (Bent, 2001; Herschorn, 1997; Steele, 2000).

Urethral injection offers a cystoscopically assisted, minimally invasive treatment of SUI. It can be performed in an office under local anesthesia and is associated with a low risk of complications. For these reasons, it is often chosen for women who wish to avoid surgery or who are not surgical candidates due to other comorbidities. Urethral injections can be performed both peri- and transurethrally. The transurethral approach is more often used and allows for more accurate placement of the bulking agent (Faerber, 1998; Schulz, 2004). Currently available agents in the United States approved for use include autologous fat and several synthetic agents described later.

PREOPERATIVE

Patient Evaluation

Complex urodynamic testing with assessment of urethral structure and function is completed. To assess for ISD, maximum urethral closure pressure or leak point pressure are specifically evaluated (Chap. 23). Additionally, urethral mobility is assessed.

Consent

Procedure efficacy is discussed, and success rates in general are lower than those for surgery. Specifically, 1-year rates of curing or improving SUI range from 60 to 80 percent (Bent, 2001; Corcos, 2005; Lightner, 2002, 2009; Monga, 1995). Continence rates diminish with time, as would be intuitive, with the breakdown of collagen and fat. However, Chrouser (2004) found similar rates of decline with time even when synthetic material was compared with collagen. Accordingly, these injections are viewed as a nonpermanent treatment of SUI, and sustained continence is found in only 25 percent of patients at 5 years following injection (Gorton, 1999).

One major advantage to urethral injection is its low associated risk of complications. Side effects of injection are generally transient and may include vaginitis, acute cystitis, and voiding symptoms. Of these, urinary retention for a few days postprocedure is the most frequent. Long-term retention, however, is not a significant risk. A more serious complication is persistent de novo urgency, which may develop in as many as 10 percent of women following injection (Corcos, 1999, 2005).

Patient Preparation

Prior to urethral injection, UTI and anatomic pathology such as urethral diverticula are excluded. Anecdotally, we have seen bulking agent migration into such diverticula. As noted, UTI can commonly follow urethral injection. Therefore, a single dose of an antibiotic to cover uropathogens is administered orally after procedure completion. Thromboprophylaxis is not typically required for this brief office procedure.

INTRAOPERATIVE

Choice of Bulking Agent

In the United States, currently used agents for urethral injection are carbon-coated synthetic microspheres (Durasphere), calcium hydroxylapatite particles (Coaptite), and polydimethylsiloxane (Macroplastique). These synthetic agents are effective. However, no randomized trials compare results among these three, and long-term data are lacking (Shah, 2012; Zoorob, 2012).

Of agents no longer used, autologous fat provided limited success for SUI due to rapid degradation and reabsorption (Haab, 1997; Lee, 2001). A bovine collagen product (Contigen) was commonly selected, but manufacturing ceased due to an inadequate supply of medical-grade collagen. Ethylene vinyl alcohol copolymer (Uryx/Tegress) was withdrawn due to urethral erosion complications.

Surgical Steps

Anesthesia and Patient Positioning

Urethral injection for most patients can be performed in an office setting with cystoscopic capability. The patient is placed in the dorsal lithotomy position, the vulva is prepared and draped, and the bladder drained. Two-percent lidocaine jelly is instilled into the urethra 10 minutes prior to the procedure. If necessary, topical 20-percent benzocaine can be used as an analgesic on the vulva, and 4 mL of 1-percent lidocaine can be injected in divided doses at the 3 and 9 o’clock positions of the external urethral orifice.

Transurethral Approach to Needle Placement

A cystoscope is positioned within the distal urethra, so that the midurethra, proximal urethra, and bladder neck are viewed simultaneously. A 22-gauge spinal needle attached to a syringe carrying the bulking agent is introduced through the cystoscopic sheath. With the bevel pointing toward the urethral lumen, the needle is directed at a 45-degree angle to the lumen and inserted through the urethral wall at the 9 o’clock position and at the level of the midurethra. After the needle tip penetrates the urethral wall, the bevel is no longer seen. The needle is then advanced parallel to the urethral lumen for 1 to 2 cm. This positions the needle at the level of the proximal urethra.

Injection

The bulking agent is injected under constant pressure, and the submucosal lining begins to rise (Fig. 45-6.1). The needle is withdrawn slowly to bulk the proximal and midurethra. Bulking agent is administered until coaptation of the mucosa has developed (Fig. 45-6.2). In general, 1 to 2 syringes (2.5 to 5 mL) of agent are used per procedure. These steps are then repeated at the 3 o’clock position.

Ideally, the number of needle holes made into the urethral wall is minimized to avoid leakage of bulking agent through these punctures. Thus, if a second syringe of agent is required to achieve coaptation, the originally positioned needle remains in place, and a second syringe of agent is attached.

Cystoscope Removal

Once coaptation of the mucosa is achieved, the cystoscope is removed, taking care not to advance proximal to the injection site. This avoids forceful compression of the deposited agent by the cystoscope tip and loss of coaptation.

POSTOPERATIVE

Women are discharged home following their first postinjection void, and single-dose oral antibiotic prophylaxis is prescribed. Women abstain from intercourse for 10 days following injection but may otherwise resume usual activities.

If urinary retention develops, then intermittent self-catheterization is begun and continued until retention resolves. For those unable to self-catheterize, a temporary Foley catheter is placed. However, catheter placement can potentially compress deposited bulking agent and diminish urethral coaptation.

Two weeks following injection, we assess treatment success. If a patient fails to achieve desired degrees of continence, additional injections are planned to improve urethral coaptation.

Urethrolysis is the loosening or release of a prior urethral suspension repair. This release is used in women with urethral obstruction symptoms including urinary retention and voiding dysfunction following suspension. It can be performed either vaginally or abdominally. A vaginal approach is predominantly used. An abdominal approach, however, may afford a better opportunity to mobilize the bladder from the pubic symphysis and may also be selected in instances in which the initial surgery was performed via laparotomy.

Debate exists as to the need of a concurrent antiincontinence procedure to compensate for urethral support lost with urethrolysis. However, in many cases, residual scarring prevents SUI, and our belief is to avoid repeating a second potentially obstructing procedure. Accordingly, this decision is individualized.

PREOPERATIVE

Patient Evaluation

In women with bladder neck obstruction, symptoms usually begin soon after initial surgery. Objective assessment with urodynamic testing is performed to determine the cause of voiding dysfunction and differentiate between a hypotonic bladder and obstruction. Obstruction may result from bladder neck obstruction or pelvic organ prolapse. Thus, a thorough examination for prolapse is completed.

Consent

In addition to usual surgical risks, bleeding may be a significant complication due to vascularity in the space of Retzius. Additionally, dissection of dense scarring around the urethra and bladder may place these structures at risk of laceration.

Due to scar tissue reformation, initial obstruction improvement can worsen over time, as scar tissue may variably reform. In contrast, postoperative incontinence may follow deconstruction of prior antiincontinence support or from denervation injury during extensive periurethral dissection.

Patient Preparation

As with all genitourinary procedures, UTI is excluded prior to surgery. Antibiotic prophylaxis is administered prior to surgery to decrease risks of postoperative wound and urinary tract infection (Table 39-6). Thromboprophylaxis is provided as outlined in Table 39-8.

INTRAOPERATIVE

Surgical Steps—Vaginal Approach

Anesthesia and Patient Positioning

Urethrolysis may be performed under general or regional anesthesia. The patient is placed in standard lithotomy position with lower extremities in candy-cane or booted support stirrups. The vagina is surgically prepared, and a Foley catheter is inserted into the bladder.

Vaginal Incision

Traction is placed on the Foley catheter to identify the bladder neck and assess the degree of scarring. A 2- to 3-cm long incision, either vertical midline or U-shaped, is made in the anterior vaginal wall. The incision site will vary along the vaginal length depending on the location of the original sling or sutures (Fig. 45-7.1). Sharp dissection is used to separate the vaginal epithelium from underlying fibromuscular tissue and is extended bilaterally toward the inferior edge of each pubic rami.

Dissection frees the urethra by dividing scar tissue or prior sling material or sutures that lie between the urethra and pubic rami (Fig. 45-7.2). If prior supporting material is identified, it may be incised or if necessary, excised. Bleeding is frequently encountered and can be controlled with direct pressure or vessel ligation.

After this lateral dissection, the periurethral tissue is perforated, and the space of Retzius is entered. Careful blunt dissection within this space and at the back of the pubic symphysis will additionally mobilize the proximal urethra. Dissection is kept close to the dorsal surface of the pubic bone to avoid cystotomy in a bladder that is generally densely adhered to the pubic bone.

Incision Closure

Following adequate mobilization of the urethra, the vaginal incision is reapproximated with a running closure using 2-0 gauge delayed-absorbable suture.

Surgical Steps—Abdominal Approach

Anesthesia and Patient Positioning

As with a vaginal approach, urethrolysis may be completed under general or regional anesthesia. For an abdominal approach, booted support stirrups and low lithotomy positioning are preferred. This positioning allows vaginal access for the surgeon’s hand during dissection and for cystoscopy. The abdomen and vagina are surgically prepared, and a Foley catheter is inserted into the bladder.

Abdominal Incision

A low transverse incision is typically preferred for this procedure to permit easy access to the space of Retzius. Either Pfannenstiel or Cherney incisions are usually selected (Sections 43-2 and 43-3). If the procedure is done in isolation, fascia of the anterior abdominal wall muscles and then transversalis fascia are incised, but entry into the peritoneal cavity is not necessary to reach the space of Retzius.

Entry into the Space of Retzius

The correct plane of dissection to enter the space of Retzius lies directly behind the pubic bone. Loose areolar tissue is gently dissected downward in a mediolateral fashion with fingers or sponge, beginning immediately behind the pubic bone. If the correct plane is entered, this potential space opens easily. However, women requiring urethrolysis have typically had prior surgery within this space. As a result, tissue can be densely adhered and sharp downward dissection along the dorsal surface of the symphysis may be preferred to enter this space (Fig. 45-7.3).

Bladder Dissection and Urethrolysis

The bladder is also typically densely adhered to the back of the symphysis. Sharp dissection with the curved surface of scissors facing the symphysis is directed against the symphysis to minimize cystotomy risk. At times, however, an intentional cystotomy may be required so that a finger can be placed inside the bladder to aid dissection (Fig. 45-7.4).

Sharp dissection is continued inferiorly and laterally down the inner surface of the symphysis and pubic bones to free the bladder and eventually also the proximal urethra. Bleeding is common during dissection and may be controlled with absorbable sutures.

Abdominal Closure

The abdomen is closed in a standard fashion (Sections 43-2 or 43-3).

POSTOPERATIVE

An active bladder test is performed following catheter removal. If large residual volumes are found, intermittent self-catheterization or Foley catheter replacement is required. If cystotomy was performed, the duration of catheterization is dependent on cystotomy size and location. For example, small cystotomies in the bladder dome typically require drainage for 7 days or less. For larger cystotomies at the bladder base, however, drainage for several weeks may be needed. Antibiotic suppression is not required with this catheter use.

Normal diet and activity can resume during the first postoperative days. With a vaginal approach, however, intercourse is postponed until the vaginal incision is well healed. Recovery from an abdominal approach follows that for laparotomy (Section 43-1).

Symptoms of voiding obstruction may develop following urethral sling procedures, specifically TVT and TOT procedures. For most patients, postoperative urinary retention resolves in days or 1 to 2 weeks. However, voiding dysfunction requiring surgery develops in up to 3 percent and generally is identified days to weeks after surgery (Jonsson Funk, 2013; Nguyen, 2012; Richter, 2010). If obstruction is diagnosed soon after the index procedure, surgical release is performed and involves simple cutting of the sling material.

PREOPERATIVE

Patient Evaluation and Preparation

Inability to fully empty the bladder may stem from urethral obstruction or a hypotonic bladder. New-onset urinary retention after a midurethral sling procedure (TVT or TOT) is usually due to sling tightness. However, other factors can be involved, such as preexisting or de novo bladder hypotonia. Thus, prior to TVT urethrolysis, urodynamic testing is often performed to prove that symptoms are due to obstruction rather than to bladder hypotonicity. Additionally, tape may erode into the bladder or urethra in cases of obstruction, and cystoscopy allows exclusion of this complication.

Perioperatively, no specific patient preparation is required, as midurethral sling release is a minor surgical procedure.

Consent

Associated with midurethral sling release, the risks of incontinence recurrence, failure to adequately relieve retention, fistula formation, and intraoperative bladder or urethral injury are discussed during consenting.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

This surgery can be performed with local, regional, or general anesthesia as an outpatient procedure. A patient is placed in standard lithotomy position within candy-cane or booted support stirrups. The vagina is surgically prepared, and a Foley catheter is inserted.

Vaginal Incision and Tape Identi­fication

A midline suburethral incision that follows the prior primary surgical incision is made sharply. Careful dissection is used to expose the sling material and to define the urethral borders. Alternatively, with prior TOT, tight tissue bands may be palpated in the sulci. In this case, the vagina can be incised at one sulcus, and the tape transected or partially excised here.

Often because of increased sling tension, sling material is stretched and measures only half its expected width. Additionally, there is usually extensive tissue ingrowth into the sling material, and identification and mobilization can be difficult. Occasionally, a sling may migrate to the proximal urethra. In these instances, the vaginal incision may require cephalad extension.

Incision of Sling Material

Following mobilization of the material, a hemostat is opened between the sling and urethra. Metzenbaum scissors are used to cut the sling material. In general, incision leads to immediate retraction of sling ends (Fig. 45-8.1, top inset). If retraction does not follow, a 1-cm segment of material is then excised (see Fig. 45-8.1, bottom inset). If the sling is deeply embedded and near the urethral lumen, one to two imbricating layers are placed through the vaginal muscularis following sling excision using 2-0 or 3-0 gauge delayed-absorbable suture.

Incision Closure

After vigorous irrigation, the vaginal epithelium is closed in a continuous running fashion using 2-0 gauge delayed-absorbable suture.

POSTOPERATIVE

Prior to discharge, an active voiding trial is performed (Chap. 42). If a Foley catheter remains, a second voiding trial can be repeated in a few days or at the surgeon’s discretion. If a woman is performing self-catheterization, this is continued until postvoid residuals fall below approximately 100 mL. Normal diet and activity can resume during the first postoperative days. Intercourse, however, should be postponed until the vaginal incision is healed.

The approach to urethral diverticulum repair varies and depends on diverticular sac location, size, and configuration. For those near the bladder neck, partial ablation is often chosen to avoid damage to the bladder neck and continence mechanism. For midurethral diverticula, simple diverticulectomy is typically performed. For those located at the external urethral orifice, again, simple diverticulectomy is preferred to the Spence procedure. The latter is rarely performed and can alter final urethral orifice anatomy. Last, for those with a complex diverticulum that may surround the urethra, a combination of techniques may be necessary. Of these options, complete vaginal excision of the urethral diverticulum is preferred (Antosh, 2011).

PREOPERATIVE

Patient Evaluation

As described in Chapter 26, urethral diverticula can be difficult to diagnose due to their often varied and nonspecific presentations. Once identified, accurate information regarding diverticular anatomy is essential to surgical planning and patient counseling. Compared with transvaginal sonography or voiding cystourethrography, magnetic resonance (MR) imaging is a superior radiographic study to delineate diverticular configuration, especially with complex diverticula (Ockrim, 2009).

Additionally, cystoscopy is valuable in locating sac openings along the urethral length and demonstrates high specificity, as transurethral visualization of an ostium is unlikely to be associated with other diagnoses. That said, our frequency of urethral diverticulum detection (sensitivity) was only 39 percent (Pathi, 2013).

Women with diverticulum can present with urinary incontinence. In such cases, we typically perform baseline urodynamic testing but generally defer antiincontinence procedures until after postoperative reevaluation.

Consent

With diverticular repair, damage to urethral continence mechanism may lead to postoperative incontinence. Alternatively, urethral stricture or stenosis or urinary retention may develop depending on the extent and location of surgery. Additionally, urethrovaginal fistula and bladder injury can result. Recurrence rates of 10 to 25 percent have been reported, especially with a horseshoe or circumferential configuration or previous surgical intervention (Antosh, 2011; Ingber, 2011). Failures are believed secondary to incomplete diverticulum excision. Moreover, urethral pain can persist or arise after diverticulectomy (Ockrim, 2009). Recurrent UTI can also persist. Last, with the Spence marsupialization technique, a distal diverticulum and urethral orifice are sharply opened together to form a large single meatus. Thus, external urethral orifice anatomy is usually altered, and a spraying pattern with urination may result.

Patient Preparation

Any acute diverticular infection or cystitis is treated prior to surgery. Preventatively, antibiotic and venous thromboprophylaxis are given as outlined in Tables 39-6 and 39-8.

INTRAOPERATIVE

Surgical Steps—Diverticulectomy

Anesthesia and Patient Positioning

Diverticulum excision is typically performed as an inpatient procedure under general or regional anesthesia. A patient is placed in standard lithotomy position within candy-cane or booted support stirrups. The vagina is surgically prepared, and a Foley catheter containing a 10-mL balloon is placed in the bladder to assist in identifying the bladder neck.

Cystourethroscopy

This procedure is performed at the procedure’s onset to attempt diverticular opening identification and exclude other abnormalities.

Vaginal Incision

To begin, a midline or U-shaped incision is made on the anterior vaginal wall over the diverticulum, and the vaginal epithelium is dissected sharply off the fibromuscular layer of the vaginal wall (Fig. 45-9.1). Ample epithelium is freed to allow adequate exposure and to permit final tissue approximation without suture-line tension.

Diverticulum Exposure

Next, the fibromuscular layer of the vagina and urethra is incised with a longitudinal or transverse incision to reach the diverticular sac. Anatomically, the distal vaginal and urethral walls are fused, and it may be difficult or impossible to separate tissue planes. Thus, sharp dissection is needed to completely mobilize the diverticular sac away from the vaginal and urethral fibromuscular layer and to the level of the diverticular sac neck (Fig. 45-9.2). During dissection, the sac may be inadvertently or intentionally entered. With this, the diverticular walls can be grasped with Allis clamps to create tension across the connective tissue fibers between the diverticular walls and the vaginal fibromuscular layer to aid dissection. Similarly, an index finger placed within the sac can recreate sac fullness to stretch these same connective tissue fibers. Dissection is then continued until the diverticulum’s communication with the urethra is isolated. Caution and awareness of urethral location are essential to avoid damage.

Diverticulum Excision

At its neck, the diverticulum is excised from the urethra (Fig. 45-9.3).

Urethral Closure

The urethral defect is closed with interrupted 4-0 gauge delayed-absorbable sutures over the Foley catheter (Fig. 45-9.4). Fibromuscular layers of the urethra and vagina are then reapproximated off tension in two or more layers. For this closure, a vest-over-pants method with 2-0 gauge delayed-absorbable suture is preferred when possible to avoid overlapping suture lines (Fig. 45-9.5). Redundant vaginal epithelium is trimmed, and the epithelium is closed in a running fashion with 2-0 gauge delayed-absorbable suture.

Surgical Steps—Partial Diverticular Ablation

If extensive dissection is required around the trigone, consideration is given to leaving the proximal portion of the sac in place to avoid direct injury or denervation injury. In addition, ureteral stents may be beneficial during the dissection.

Vaginal Incision

Again, a midline or U-shaped incision is made on the anterior vaginal wall over the diverticulum, and the vaginal epithelium is dissected sharply off the fibromuscular layer of the vaginal wall. Ample epithelium is freed to allow adequate exposure and later defect closure off tension. The Foley catheter and balloon can be placed on gentle tension to aid in identifying the bladder and bladder neck to avoid injury.

Diverticulum Exposure

A longitudinal incision is made through the fibromuscular layer to the diverticular sac, and sharp dissection is used to completely mobilize and expose the sac. The diverticulum is opened, and the communication with the urethra is identified. To avoid injury to the proximal urethra and bladder neck, the diverticular sac, but not the neck of the diverticulum, is sharply excised. As much of the sac as can be accessed is removed.

Sac Closure

The base of the sac is then sutured side to side with 3-0 gauge delayed-absorbable suture to cover the urethral defect. A second, and possibly a third, imbricating layer using the vaginal muscularis is created with similar suture. Excess vaginal epithelium that had previously covered the diverticulum is excised. The vaginal epithelium is closed in a running fashion with a 2-0 gauge delayed-absorbable suture.

Surgical Steps—Spence Marsupialization

External Urethral Orifice Incision

Tips of Metzenbaum scissors are inserted into the urethral orifice and vagina. An incision is made that incorporates and simultaneously incises the posterior urethral wall, entire thickness of the diverticulum, and distal anterior vaginal wall. By this incision, the external urethral orifice ring is opened and its communication into the diverticular sac is enlarged.

Marsupialization

For marsupialization, cut edges of the diverticular sac are reapproximated to the vaginal epithelium in a running pattern using 4-0 gauge delayed-absorbable suture. Ultimately, the urethral orifice is widened by this incorporation of the diverticular sac diameter.

POSTOPERATIVE

Catheter management is an important aspect of postoperative care. Although no consensus guidelines exist, most experts recommend catheter placement for 5 to 7 days. Surgeries of increasing complexity may require longer duration. Antibiotic suppression is not required with this catheter use. Normal diet and activity can resume during the first postoperative days. Intercourse, however, is postponed until the vaginal incision is well healed.

Vesicovaginal fistulas may be repaired either vaginally or abdominally. A vaginal approach is preferred for most fistulas seen in the United States, which are posthysterectomy, apical fistulas. This approach offers comparable success rates, lower morbidity, and faster patient recovery. Of vaginal methods, the one most commonly performed by gynecologists is the Latzko technique. With this, surrounding vaginal epithelium is reflected away from the fistulous tract. The tract is then resected, but the portion into the bladder is not excised. This avoids a large bladder defect, which can develop with resection of even relatively small fistulas. Following excision, layered closure of the vaginal incision seals the leak. If performed for fistulas at the vaginal apex, then both anterior and posterior vaginal wall epithelia are reflected for tract access. In this location, the final layered closure simulates the steps of colpocleisis, and thus the Latzko technique for apical fistulas is often likened to a proximal partial colpocleisis.

Alternatively, in some cases, the fistulous tract can be completely excised vaginally, and a layered repair of the bladder and then vaginal wall follows. This is preferred by many if the fistulous opening is less than 5 mm in diameter and distant from ureteral orifices.

At times, an abdominal approach may be necessary for women in whom fistula location prohibits effective surgical access or in whom prior vaginal repairs have been unsuccessful. The most commonly described abdominal approach, termed the O’Conor technique, is outlined here and involves bisecting the bladder wall to enter the fistulous tract. Modifications to this as well as an extravesical approach have been described, especially during laparoscopic or robotic routes to fistula repair (Miklos, 2015). With any abdominal approach, omentum or peritoneum can be mobilized and interposed between the bladder and vagina in an attempt to prevent recurrence.

One principle of fistula repair dictates that a repair be performed in noninfected and noninflamed tissues. A second states that tissue must be approximated without excess tension. Last, a multilayer, watertight closure aids reestablishment of bladder integrity. If these guidelines are followed, success rates are typically good and approximate 95 percent (Rovner, 2012). In the United States, most fistulas follow hysterectomy for benign causes, and repair of these fistulas is associated with high cure rates. In contrast, fistulas associated with gynecologic cancer and radiation therapy may require adjunctive surgical procedures such as vascular or myocutaneous flaps. These flaps provide supportive blood supply to defects that develop in poorly vascularized or fibrotic tissue. Even with these measures, success rates are lower.

PREOPERATIVE

Patient Evaluation

Prior to repair, a fistula should be well characterized, and complex fistulas with multiple tracts or a primary or concomitant ureterovaginal fistula should be identified. Proper evaluation typically includes cystoscopy and imaging that displays the upper and lower urinary tract such as CT urography (pyelography) or intravenous pyelography (IVP) (Fig. 26-2). Ureterovaginal fistulas are usually associated with upper tract abnormalities such as hydroureter and hydronephrosis. Therefore, normal IVP or CT findings are reassuring that ureteral involvement is absent. Additionally, this imaging complements cystoscopy in ascertaining the proximity of ureters relative to a fistula for surgical planning. In general, routine posthysterectomy vesicovaginal fistulas develop midline at the vaginal apex and usually away from the ureters, which enter the bladder at the midlength of the vagina. However, lateral fistulas raise concern for ureteral involvement or proximity.

Whether or not surgery can be performed vaginally largely depends on the ability to adequately expose the fistula. Thus, during physical examination, a surgeon assesses if a fistula can be brought down into the surgical field and if a patient’s pelvis affords adequate space. Some degree of prolapse of the vaginal apex is helpful for fistula repair. However, a final decision on the repair route is sometimes made intraoperatively, when muscle relaxation from anesthesia allows better assessment of access.

Additionally, tissue infection or inflammation is sought, and if it is identified, fistula repair is delayed until resolution. Fistulas recognized within a few days following hysterectomy may be repaired immediately, prior to the brisk inflammatory response. However, if surgical repair is not undertaken within a few days following the initial surgery, a delay of approximately 6 weeks is recommended to permit tissue inflammation abatement.

Consent

Fistulas may redevelop following repair, and patients are counseled that initial surgery may not be curative. With the Latzko procedure, the vagina is moderately shortened in most cases. Thus, the risk of postoperative dyspareunia is included during surgical consenting. However, a recent study showed that fistula repair improves sexual function and quality of life, with no attributed difference between vaginal and abdominal routes (Mohr, 2014).

Patient Preparation

Immediately prior to surgery, intravenous antibiotics and thromboprophylaxis are commonly administered (Tables 39-6 and 39-8). The necessity of bowel preparation for this procedure is unclear, and administration is individualized.

INTRAOPERATIVE

Surgical Steps—Vaginal Repair

Anesthesia and Patient Positioning

In most cases, repair is performed with general or regional anesthesia, and postoperative hospitalization is individualized. The patient is placed in standard dorsal lithotomy position, and the vagina is surgically prepared. If ureters lie close to a fistula, ureteral stents are placed. Cystoscopy is required during the procedure to document ureteral patency and assess bladder integrity.

Delineating a Fistulous Tract

Initially, the course of a fistulous tract is identified. If a tract is wide enough to accept a pediatric catheter, the tube is threaded through the fistulous tract, and the balloon is inflated within the bladder. If a tract cannot be delineated in this manner, then lacrimal duct probes, ureteral stents, or other suitable narrow dilators are used to trace the tract course and direction. Subsequently, attempts are made to dilate the tract and place a pediatric catheter.

Exposure

For repair, the fistula is brought into the operative field. If catheterization of the tract is possible, tension on the catheter will allow this. Alternatively, four sutures can be placed in the vaginal wall surrounding the fistula and used to pull the fistula into the operative field (Fig. 45-10.1). Some advocate performing a mediolateral episiotomy to gain exposure, although this is not our practice.

Vaginal Incision

A vaginal incision is made circumferentially approximately 1 to 2 cm around the fistulous tract (Fig. 45-10.2). Vaginal epithelium surrounding the tract is sharply mobilized laterally and away from vaginal fibromuscular wall and then excised with Metzenbaum scissors.

Tract Excision

The fistula tract may or may not be totally excised to the level of the bladder. As noted earlier, complete tract excision creates a larger bladder defect for repair. Also, we prefer not to excise a fistulous tract lying near a ureteral orifice to avert potential ureteral injury and need for reimplantation (Blaivas, 1995).

Fistula Closure

If a tract is totally excised, the bladder mucosa is reapproximated with 3-0 gauge delayed-absorbable suture in an interrupted or running fashion. Following this closure, the bladder is retrograde filled with at least 200 mL of fluid to exclude leaks. If a defect is found, additional reinforcing sutures are placed until a watertight repair is achieved.

Regardless of whether the tract is completely or partially excised, anterior and posterior bladder and vaginal muscular layers are then approximated over the fistula site. For this, an interrupted or running suture line of 3-0 or 2-0 gauge delayed-absorbable sutures is created (Fig. 45-10.3). Beginning proximally and adding distally, sequential suture lines are layered (Fig. 45-10.4).

After muscular layers of the bladder and vaginal walls are closed, the vaginal epithelium is closed in a continuous running fashion using 3-0 or 2-0 gauge delayed-absorbable suture.

Cystoscopy

Cystoscopy is again performed to document ureteral patency and to inspect the incision site.

Surgical Steps—Abdominal Repair

Anesthesia and Patient Positioning

In most cases, abdominal repair is performed under general anesthesia. The patient is placed in low lithotomy position within booted support stirrups. With the patient’s thighs parallel to the ground and the legs separated, access to the vagina is maximized. The abdomen and vagina are surgically prepared, and a Foley catheter is inserted.

Abdominal Incision and Bladder Entry

A low transverse or midline abdominal entry incision can be used. If mobilization of the omentum is anticipated, a vertical midline incision can provide greater access to the upper abdomen. A Maylard or Cherney incision may alternatively be selected (Section 43-3). After the peritoneum is entered, the abdomen is explored, bowel is packed from the operating field, and a self-retaining abdominal wall retractor is placed. The space of Retzius is opened using the technique described on page 1061. Next, a vertical midline extraperitoneal incision is made into the bladder dome. Prior to this incision, pushing the Foley balloon up or filling the bladder helps avoid grasping and then cutting the posterior bladder wall.

Fistulous Tract Delineation and Ex­cision

After cystotomy, the fistula and ureteral orifices are seen from within the bladder. If the fistulous tract is near the orifices, ureteral stents are placed. From the dome, the cystotomy incision is extended over the top and then back of the bladder to reach the circular fistulous opening (Fig. 45-10.5). A lacrimal probe or catheter may be placed into the fistulous tract to delineate its course. The tract is then excised.

In contrast and less commonly, if a fistula tract lies close to the trigone, extension of the bladder incision to the fistulous tract may not be desired, as the resulting bladder defect would be extensive. In these cases, the entire fistulous tract is directly excised using only the bladder dome incision. However, vascular flap interposition with this approach is limited as the bladder wall is not significantly dissected off the vaginal wall.

Separation of the Bladder and Vagina

In cases with bladder bisection, sharp dissection is used to separate the vagina away from the bladder in the area of the fistula (Fig. 45-10.6). Scarring may be extensive, and sharp rather than blunt dissection is preferred. To assist, the rounded tip of an end-to-end anastomosis (EEA) sizer can be placed in the vagina to manipulate and accentuate the dissection plane (Fig. 46-21.4). The vagina is widely separated from the bladder to allow omentum or peritoneal flap placement between the two.

Vaginal Closure

The vagina is closed in one or two layers with 2-0 gauge delayed-absorbable suture and running or interrupted stitches (Fig. 45-10.7). The EEA sizer or fingers within the vagina can accentuate the vaginotomy margins to aid closure.

Bladder Closure

The entire bisecting bladder incision is closed in two or three layers using running sutures of 3-0 gauge absorbable suture (Fig. 45-10.8). As with the vaginal approach, after the first layer, the bladder is retrograde filled with at least 200 mL, and incision-line leaks are sought. If defects are noted, additional reinforcing sutures are placed to achieve a watertight repair. During bladder closure, each subsequent layer is imbricated such that the preceding suture line is covered and tension is released (Fig. 45-10.9).

If the bladder is not bisected and the fistulous tract is directly excised solely through the bladder dome cystotomy, then the muscular wall of vagina is first repaired in one or two layers as in Step 5. Second, the bladder wall at the fistula excision site is closed in one or two layers using a running stitch of 3-0 absorbable suture. Next, the bladder mucosa is reapproximated with a single-layer running stitch of 3-0 absorbable suture. Last, the entry bladder dome incision is closed similarly, except the bladder mucosa is reapproximated first and followed by bladder wall closure in layers.

Omental or Peritoneal Interposition

As described in Section 46-14, the omentum can be mobilized to create a J-flap. The omentum is then sutured to the anterior wall of the vagina to cover the incision line (Fig. 45-10.10). This provides a tissue layer between vagina and bladder, increases vascular flow to the area, and may improve tissue healing. Alternatively, if the omentum cannot be mobilized, peritoneum, although less vascular, can be interposed and creates another barrier layer between the bladder and vagina (Fig. 45-10.11).

Cystoscopy

Cystoscopy is performed to document ureteral patency and inspect the incision site.

Incision Closure

The abdominal incision is closed as described in Chapter 43.

POSTOPERATIVE

The bladder is drained postoperatively to prevent overdistention and suture disruption. Either transurethral or suprapubic catheter placement will ensure adequate drainage in the immediate postoperative period. At our institution, we generally continue catheterization for at least 2 weeks following vesicovaginal fistula repair. Antibiotic suppression is not required with this catheter use.

This vascular graft contains the fat pad overlying the bulbospongiosus (formerly called bulbcocavernosus) muscle and brings a supportive blood supply to repairs involving avascular or fibrotic tissue. As such, this graft is commonly used in complex urethral diverticulum excisions or in complex rectovaginal or vesicovaginal fistula repairs. However, of these indications, there is some evidence supporting successful repair of certain recurrent fistulas without vascular graft interposition (Miklos, 2015; Pshak, 2013).

During graft placement, one end of the bulbocavernosus fat pad is dissected free and subsequently brought to the repair site through the primary vaginal incision. Thus, due to its anatomic origin and limited length, this fat pad, when indicated, is selected for defects involving the low to mid-vagina.

PREOPERATIVE

Patient Evaluation

In most instances, graft placement is anticipated for those with prior radiation or with fistula recurrence. Thus, preoperative planning includes assessment of tissue vascularity, connective tissue strength, and ability to adequately mobilize vaginal tissues to create a multilayered repair closure. For this procedure, a woman must have adequate labial fat, which is also assessed prior to surgery.

Consent

During consenting, women are informed of the potential for postoperative vulvar numbness, pain, paresthesias, or hematoma. Because one of the labia majora is repositioned as the graft, patients are counseled regarding the cosmetic consequences.

Patient Preparation

Because of the risk of poor wound healing in these complicated repairs, antibiotic prophylaxis listed in Table 39-6 is warranted. Thromboprophylaxis is given as outlined in Table 39-8. The necessity of bowel preparation for this procedure is unclear, and administration is individualized based on concomitant procedures.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

In most cases, a Martius flap graft and fistula repair can be performed with general or regional anesthesia, and the need for postoperative hospitalization is individualized. The patient is positioned in standard lithotomy position, the vagina is surgically prepared, and a Foley catheter is inserted.

Fistula or Diverticulum Repair

The specific defect is repaired as outlined in its respective section of this chapter.

Labial Incision

After repair completion, the lateral margin of one labium majus is incised (Fig. 45-11.1). The length of the incision is tailored to specific labial anatomy and graft size needed. In many cases, a 6- to 8-cm incision is made beginning below the level of the clitoris and is extended inferiorly.

Mobilization of the Fat Pad

The vulvar incision edges are retracted laterally, and sharp dissection is used to free the labial fat pad (Fig. 45-11.2). This tissue is vascular, and vessels ideally are ligated or coagulated prior to transection. For rectovaginal fistulas, a broad base is left inferiorly, and the fat pad is detached superiorly. For vesicovaginal and urethrovaginal fistulas or urethral diverticula, the broad base of the pad is maintained superiorly, while the fat pad is detached inferiorly. In each instance, releasing the pad with this specific polarity anatomically permits the largest possible graft to cover the repair site. Occasionally, bilateral fat pads are needed.

Graft Placement

After the pad is freed, a tunnel is created by bluntly dissecting with a hemostat that travels from the vulvar incision, underneath the vaginal epithelium, and to the vaginal incision at the repair site. The tunnel must be sufficiently broad to avoid vascular compression and graft necrosis. A suture is placed at the graft tip and used to pass the graft through the tunnel and into the vagina (Fig. 45-11.3).

Graft Fixation

The graft is secured to the vaginal muscularis overlying the repair site with several interrupted stitches using 3-0 gauge delayed-absorbable suture (Fig. 45-11.4).

Incision Closure

With hemostasis established, the vulvar incision is closed along its length using continuous or interrupted stitches of 3-0 gauge delayed-absorbable sutures. For a deep cavity at the harvest site, fatty tissue may be reapproximated in layers to close this space with several interrupted 2-0 or 3-0 gauge delayed-absorbable sutures. Alternatively, a drain may be placed in the cavity. The vaginal epithelium overlying the defect repair is closed in a continuous running fashion using 3-0 gauge delayed-absorbable suture.

POSTOPERATIVE

Care after surgery is predominantly dictated by the associated defect repair. Ideally, the vaginal and perineal sites are kept dry rather than wet, and baths are avoided during the first 6 weeks. After each void or stool, patients rinse with a water-filled squirt bottle and gently pat dry.

Sacral neuromodulation or sacral nerve stimulation (SNS) electrically stimulates the sacral nerves to modulate reflexes that influence the bladder, sphincters, and pelvic floor (Noblett, 2014). Currently, the InterStim System is the only implantable SNS device that is Food and Drug Administration (FDA)-approved for the following primary indications: urgency-frequency, urgency urinary incontinence, nonobstructive urinary retention, and fecal incontinence. Although not FDA-approved for chronic pelvic pain, interstitial cystitis/painful bladder syndrome, or chronic idiopathic constipation, it may sometimes be used if these symptoms coexist with the previously listed primary indications. This surgery is typically offered to women who have failed to adequately improve with multiple other conservative therapies. The mechanism of action is unclear, but one explanation describes modulation of reflex neural pathways involved with bladder storage and emptying and with innervation of the pelvic floor. Of these, pudendal afferent somatic fibers are thought to play an important role (deGroat, 1981; Gourcerol, 2011).

SNS is generally completed in two phases. First, during a test phase, a slender, 30-cm long permanent lead that conducts electrical impulses to its tip is placed into one posterior sacral foramen and adjacent to a sacral nerve root, most commonly S3. This lead is connected to a temporary external pulse generator to permit an efficacy trial lasting 1 to 2 weeks. If symptoms are decreased by at least 50 percent, then the patient is deemed a suitable candidate for permanent generator implantation. During the second or implantation phase, the lead is connected a permanent implantable pulse generator (IPG), and the IPG is tucked within a subcutaneous pocket created in the buttock. This staged approach is illustrated in these atlas pages.

A variation of these classic steps, termed percutaneous nerve evaluation (PNE), in­serts a temporary lead through the S3 foramen in the office, under local anesthesia, and generally without fluoroscopic guidance. However, despite these advantages, the trial period with PNE is brief (3 to 7 days), and the less securely anchored temporary lead more easily migrates away from the target nerve.

PREOPERATIVE

Patient Evaluation

Preoperative testing will vary depending on the indication. For urinary symptoms, women undergo full evaluation including urodynamic testing, voiding diary, cystoscopy, and other selected tests described in Chapter 23. For fecal incontinence, colonoscopy, endoanal sonography, manometry, and possibly pudendal nerve testing, described in Chapter 25, are completed during evaluation.

Consent

Failure to significantly improve symptoms may follow either SNS phase. However, approximately 70 percent of those who undergo permanent IPG implantation achieve a greater than 50-percent symptom improvement (Van Kerrebroeck, 2012). Pain at the IPG site and superficial wound infection may also complicate either phase. Long-term adverse changes include altered bowel or bladder function, undesirable sensations, neurostimulator site numbness, lead migration, and surgical device revision, replacement, or required removal. The IPG device is a relative contraindication for MR imaging, although certain IPG models permit head imaging.

Patient Preparation

A single prophylactic antibiotic dose may or may not be administered according to surgeon preference. Although not rigorously studied, prophylaxis is recommended by some due to needle passage from skin to perineural tissue in the presacral space. Thromboprophylaxis is typically not required given the procedure’s short duration.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

Although the procedure can be performed using local anesthesia and intravenous sedation, we prefer general anesthesia for the test phase. Importantly, neuromuscular blockade prohibits adequate motor response evaluation and is contraindicated. The patient is positioned prone on a Wilson frame or with a pillow under the lower abdomen to flex the hip 30 degrees for easier access to the sacrum. Pillows are also placed under the shins to allow the toes to move freely during test stimulation. The drape is positioned to permit inspection of the pelvic floor and soles for muscle responses. The area from the lower back to the perineum is surgically prepared. A Foley catheter is typically not required due to the surgery’s brevity.

Identification of S3 Foramina

These landmarks for lead placement are located approximately 9 cm above the coccyx and 1 to 2 cm lateral to the midline (Fig. 45-12.1). Fluoroscopy is currently the most common method of identifying the necessary bony landmarks intraoperatively. The fluoroscopic C-arm is draped and moved into the anteroposterior (AP) position to allow mapping of the sacral region including foramina. With this, the skin overlying the S3 foramina is outlined with a surgical marker.

Foramina Needle Insertion

An insulated foramen needle is inserted through the skin at a site approximately 2 cm lateral to the midline, 2 cm superior to the sciatic notch, and cephalad to the inked outline of the foramen. The needle is guided at a 60-degree angle caudally until the S3 foramen is penetrated. Optimally, the needle is placed into the medial and superior aspect of the S3 foramen. The needle penetrance depth, which is usually 2.5 to 4.0 cm, is confirmed and adjusted with fluoroscopic guidance by a laterally positioned C-arm.

Once in place, the needle is used to conduct electrical test impulses to the S3 nerve. This nerve contracts the levator ani muscles to create an inward retraction or “bellows” movement. S3 stimulation also causes the great toe to flex downward, that is, plantar flexion. In anesthetized patients, a sensory response cannot be elicited, but evidence suggests that motor responses may be more or at least as predictive of success (Cohen, 2006; Govaert, 2009; Peters, 2011). The typical patient sensation with S3 stimulation is a tapping or vibration in the vagina, rectum, or perineum. Once the desired S3 motor reflexes are obtained (“bellows and toe”), lead placement is initiated. If these are absent, needle depth or angle is adjusted to achieve the desired responses. Also, a needle in the contralateral foramen or in a foramen up or down one vertebral space may be tried.

Lead Placement

Once positioned, the stylet present within the foramen needle is removed and replaced with a guide wire to the appropriate depth. The foramen needle is then removed while holding the guide wire in place. A small incision is made on either side of the guide wire, and a combined introducer sheath/hollow dilator tool is then slid over the guide wire to occupy the foramen needle’s former position. The hollow dilator is unscrewed from the introducer sheath, and the dilator and guide wire are removed together. This leaves only the introducer sheath in place.

Next, using fluoroscopy, the long, flexible lead is passed down the introducer sheath into the S3 foramen. To aid threading, the lead contains a temporary stiff inner stylet. A recently introduced curved stylet better follows anatomic contours to position the lead close to the nerve root (Jacobs, 2014). The lead also contains four circumferential electrode bands arranged in series at its tip, and proximal to these lie four plastic barbs or tines to ultimately anchor the lead within soft tissues (Fig. 45-12.2).

With correct lead positioning as shown, the most proximal of the four electrode bands are fluoroscopically visible just anterior to the sacrum. All four electrodes on the lead should conduct pulses and elicit S3 motor responses. If necessary, the lead can be repositioned within the foramen. Once correctly positioned, the introducer sheath and then the curved lead stylet are removed. As the introducer sheath is removed, the four tines or barbs lock into place. Thus, the lead cannot be retracted after this point. All four electrodes are again tested to confirm the previously observed responses.

If lead advancement is needed, its stylet is replaced and the lead advanced. Retraction is more problematic. The lead is removed using gentle traction, and Steps 3 and 4 are repeated. The desired range of stimulation amplitude to achieve desired motor responses is 1 to 2 milliamps. Responses at lower amplitudes may indicate that the lead lies too close to the nerve, whereas requisite higher amplitudes can decrease battery longevity.

Pulse Generator Incision and Lead Passage

Several centimeters below the iliac crest, a 4-cm transverse incision is made over the lateral portion of the buttock that is ipsilateral to the selected foramen. Sharp and blunt dissection is used to create a deep pocket that can house the extension device for the temporary external pulse generator and eventually, the permanent IPG. The pocket should remain above the gluteal muscle fascia but is made sufficiently deep to accommodate the final IPG.

After the pocket is created, a pointed passing device is used to create a narrow tunnel between the lead and the pocket (Fig. 45-12.3). The core of the passing device is removed, leaving a hollow straw within the tunnel (inset). The lead is then manually threaded laterally through this straw and into the pocket. The straw is then removed laterally.

Placement of the Extension Device (First Phase)

Within the subcutaneous pocket, the lead is next connected to an extension wire that serves to join the lead to the temporary pulse generator (Fig. 45-12.4). A stab incision is then created lateral to the pocket. The passing device is again used and, this time, guides the extension wire through a second tunnel between the pocket and stab incision. The subcutaneous tissue is then closed over the connector in the pocket with 2-0 gauge delayed-absorbable suture in an interrupted or running fashion. The skin is closed with a subcuticular stitch using 4-0 gauge delayed-absorbable suture or with other suitable skin closure methods. Similarly, the stab incision is closed. Last, the extender wire is joined to a temporary external pulse generator, which is used for 1 to 2 weeks (see Fig. 45-12.4).

Implantable Pulse Generator Place­ment (Second Phase)

If significant symptom relief is obtained, the permanent IPG is placed 1 to 2 weeks after initial surgery. The procedure is performed with the patient prone and usually with general anesthesia for airway control. The buttock incision is opened down to the connector. The connector and extension wire are removed. The permanent IPG is connected to the lead, and then placed into the subcutaneous pocket (Fig. 45-12.5). The incision is closed again as in Step 6.

POSTOPERATIVE

Pain or erythema at the incision site suggests cellulitis, abscess, or seroma. These symptoms are evaluated as soon as possible, and antibiotics are instituted if needed. Unusual pain is also evaluated immediately as this could suggest lead malfunction. A woman can turn the device off by herself if necessary. Primary symptoms are continually assessed postoperatively, and the IPG is reprogrammed as needed. Reprogramming the device or changing leads will often lead to symptom improvement.

The anterior vaginal wall is the most frequent site of clinically recognized prolapse (Brincat, 2010). One method to correct this is anterior colporrhaphy, which reapproximates attenuated fibromuscular tissue between the vagina and bladder to elevate the bladder to a more anterior and anatomically normal position. Anatomic success rates following this surgery are modest at 1 year (Altman, 2011; Weber, 2001). Thus, strategies to improve these colporrhaphy rates include: (1) concurrent vaginal paravaginal defect repair (PVDR), (2) concurrent apical support surgeries, or (3) synthetic or biologic mesh placement instead of or in addition to colporrhaphy.

Of these, PVDR attempts to provide lateral support to the anterior vaginal wall. However, the vaginal PVDR is less favored as its required dissection creates a large defect within tissue that carries significant nerves and vessels. Also, efficacy data are lacking.

Synthetic mesh placement is associated with improved anterior prolapse anatomic outcomes (61 versus 35 percent) (Altman, 2011). But this disparity in anatomic success does not always reflect symptom success rates (Chmielweski, 2011). Symptom improvement rates for mesh range from 75 to 96 percent compared with ranges of 62 to 100 percent for native tissue (Lee, 2012). Moreover, mesh use significantly increases risks of mesh erosion, vaginal lumen narrowing, and pelvic abscess (Maher, 2013). These may be associated with dyspareunia, urinary complaints, and chronic pelvic pain (Food and Drug Administration, 2011). Currently, few data guide patient selection for mesh placement, which may be best reserved for those with recurrent prolapse or those with medical comorbidities that preclude alternative procedures (American College of Obstetricians and Gynecologists, 2011). Moreover, surgeons using mesh need adequate training and experience, and patients are educated regarding risks and benefits. Alternatively, cadaveric fascia has been similarly used, but surgical success using this tissue is not significantly improved compared with colporrhaphy alone (Gandhi, 2005).

Last, increasing data suggest that vaginal apex support plays a critical role in anterior vaginal wall suspension (Lowder, 2008; Summers, 2006). Thus, anterior colporrhaphy is now often complemented by apical support procedures.

PREOPERATIVE

Patient Evaluation

As stated, women with anterior wall prolapse often have other compartment defects, and a complete POP-Q examination, described in Chapter 24, aids surgical planning. In addition, anterior vaginal wall prolapse is frequently associated with stress urinary incontinence (SUI) (Borstad, 1989). Even those who are continent, however, may have occult SUI unmasked following prolapse correction. Thus, preoperative urodynamic evaluation is often recommended. During this evaluation, the prolapse is reduced to its anticipated postoperative position to mimic pelvic floor anatomy and dynamics following surgery (Chaikin, 2000; Yamada, 2001). The decision to perform a concurrent prophylactic antiincontinence procedure is then dictated by individual urodynamic findings and adequate patient counseling.

Consent

For most women, anterior colporrhaphy has low complication rates. Of these, recurrence of the anterior vaginal wall defect is one of the most frequent. De novo SUI described earlier, prolonged catheter use for urinary retention, and voiding dysfunction are also discussion points. Although infrequent, postoperative dyspareunia is another cited complication. However, preoperative symptoms related to sexual function in general improve with anterior colporrhaphy (Weber, 2001). Uncommonly, serious hemorrhage, cystotomy, or ureteral injury may occur intraoperatively.

If mesh is used, these latter risks may be increased, and bowel or ureteral injury is possible. Accordingly, intraoperative cystoscopy is recommended. Less common short-term postoperative mesh complications include wound infection or hematoma. Long-term data from randomized trials show mesh erosion rates that range from 5 to 19 percent; chronic pain, up to 10 percent; and dyspareunia, 8 to 28 percent (American College of Obstetricians and Gynecologists, 2011).

Patient Preparation

Bowel preparation is generally not indicated for isolated anterior colporrhaphy but may be recommended at the surgeon’s discretion if other compartmental repairs are planned. Antibiotic prophylaxis with a first- or second-generation cephalosporin is recommended immediately prior to surgery as cystoscopy is also performed. Thromboprophylaxis is given as outlined in Table 39-8.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

After adequate general or regional anesthesia is administered, a patient is placed in standard lithotomy position, the vagina is surgically prepared, and a Foley catheter inserted. A short Auvard weighted speculum may be positioned to retract the posterior vaginal wall.

Concurrent Surgery

Anterior colporrhaphy can be performed with the uterus in situ or alternatively, following hysterectomy. If other reconstructive surgeries are required, they may precede or follow anterior colporrhaphy.

Vaginal Incision

In those with prior hysterectomy and adequate apical support, two Allis clamps are placed on each side of the midline, 1 to 2 cm distal to the vaginal apex or at the upper extent of the anterior vaginal wall prolapse (Fig. 45-13.1) Clamps are gently pulled laterally to create tension, and the vaginal wall between them is incised transversely. If hysterectomy precedes the repair, the two Allis clamps are placed at the opened cuff edge on either side of midline.

A third clamp is placed in the midline vaginal wall, 3 to 4 cm distal to the apical transverse incision. All three clamps are held, creating gentle outward tension. Metzenbaum scissors tips are insinuated beneath the epithelium in the midline of the previously made transverse incision and directed away from the vaginal apex. Scissor blades are opened and closed, while the surgeon exerts gentle forward pressure that is parallel to and within the plane beneath the vaginal epithelium. This technique allows separation of the epithelium from the fibromuscular layer. This dissection continues caudad to reach the distal, midline Allis clamp. The undermined vaginal wall is then incised in the midline longitudinally. The midline Allis clamp is then replaced more distally, and the process continues until the vaginal epithelium has been divided to within 2 to 3 cm of the external urethral opening (Fig. 45-13.2). This ending spot corresponds to a midpoint along the length of the urethra. If the anterior wall prolapse does not extend distally beyond the bladder neck, then the distal epithelial incision terminates at the neck. In addition, if a concurrent midurethral sling is planned, the colporrhaphy incision terminates just proximal to the bladder neck to allow a separate incision for sling placement.

Lateral Dissection

Along the freed epithelial edges, additional Allis or Allis-Adair clamps are placed to create gentle outward tension, while the vaginal epithelium is dissected laterally off the vagina’s fibromuscular wall (Fig. 45-13.3). This is accomplished with one finger placed behind the epithelium to accentuate the dissection plane, while scissors are held parallel to the vagina and cut connective tissue fibers between the epithelium and fibromuscular layer. Once the desired tissue plane is entered, a combination of sharp and blunt dissection readily separates the layers. Simultaneous countertraction on the fibromuscular layer by an assistant using tissue forceps or a gauze-covered finger can aid dissection. This separation is extended laterally toward the pelvic walls until substantial fibromuscular tissue is exposed to permit midline plication. The steps are then repeated on the contralateral side.

Traditional Anterior Colporrhaphy

Plication of the fibromuscular layer to the midline is then begun. For this, an interrupted stitch of 2-0 gauge delayed-absorbable suture is placed on one side of the midline beginning nearest the apex. This same needle and suture are carried to the other side of the midline, and a mirror stitch is placed the same distance from the apex. To plicate tissue, the bites of each stitch are generously spaced to bring together the wide lateral span of attenuated tissue. However, excessive tension is avoided to prevent sutures from pulling through the fibromuscular tissue or from significantly narrowing the vagina. As sutures are tied, the midline bladder bulge is elevated by the surgeon gently upward and away from the incision line. Such plication creates a firm fibromuscular wall layer to support the bladder and if indicated, the urethra (Fig. 45-13.4).

Vaginal Paravaginal Defect Repair

If vaginal PVDR is to be performed, the vaginal dissection described above is extended laterally to the pelvic side walls at the level of the arcus tendineus fascia pelvis (ATFP) (Chap. 38). Dissection also generally extends from the dorsal surface of the pubic bones to the ischial spines. Blunt dissection is typically used to enter the space of Retzius. If a paravaginal defect is present, the space is easily entered. Visualization of the pelvic sidewall is aided by Breisky-Navratil and lighted retractors. If present, the ATFP appears as a white line running from pubic bone’s dorsal surface to the ischial spine. In some cases, the ATFP is attenuated and indistinct, and stitches are instead anchored to the obturator internus muscle’s investing fascia. For repair, a series of four to six 2-0 gauge permanent sutures are placed in the ATFP or obturator fascia and attached to the paravaginal connective tissue (Fig. 45-13.5).

Incision Closure

Depending on the size of the original anterior wall defect, some redundant vaginal wall will likely be present and require trimming (see Fig. 45-13.4). Liberal trimming, however, can place the vaginal wall incision on excessive tension, affect wound healing, and narrow the vagina. The vaginal epithelium is reapproximated in a running fashion with a 2-0 gauge delayed-absorbable suture.

Mesh Placement

Various marketed mesh kits are available, and full descriptions for placement are provided by individual manufacturers. In general, a broad mesh sling supports the proximal anterior vaginal wall and has mesh arms that extend and anchor to the sacrospinous ligaments (SSLs) to provide apical support. Concurrently, the distal extent of the mesh ends at the level of the bladder neck.For placement of anterior and apical mesh repair kits, the paravesical space is entered by lateral dissection similar to the steps for vaginal PVDR (Step 6). The ATFP and the ischial spines are palpated. A finger also slides medially over the SSL. The recommended fixation point on this ligament is 2 to 3 cm medial to the ischial spine, which is similar to the fixation point for the traditional SSL fixation procedure.

Cystoscopy

Kwon and coworkers (2002) performed cystoscopy following 346 anterior colporrhaphy procedures and found unexpected injury in 2 percent of cases. These each required suture removal and replacement. Accordingly, cystoscopy is warranted to document integrity of the ureteral orifices, bladder, and urethral lumen.

POSTOPERATIVE

For most women, recovery following anterior colporrhaphy is rapid and associated with few complications. Urinary retention or UTI, however, is common. Prior to discharge, an active voiding trial is performed. If a Foley catheter remains, a second voiding trial can be repeated in a few days or at the surgeon’s discretion.

As with other vaginal surgery, diet and activity can be advanced as tolerated. Women, however, abstain from intercourse until wound healing is complete, typically at 6 to 8 weeks following repair.

Paravaginal defect repair (PVDR) is a prolapse procedure that aims to correct lateral defects in the anterior vaginal wall. The procedure involves attachment of the lateral vaginal wall to the arcus tendineus fascia pelvis (ATFP) (Fig. 38-24). This procedure is rarely performed alone and is more often combined with other prolapse procedures, especially abdominal sacrocolpopexy. PVDR is ineffective treatment for stress urinary incontinence (SUI). That said, abdominal PVDR may be performed in conjunction with the antiincontinence Burch colposuspension if a lateral anterior wall defect and prolapse complaints coexist with SUI. PVDR can also be performed laparoscopically or robotically by those with advanced skills. If sutures can be placed the same as in the abdominal approach, the results are expected to be equivalent, but data are limited.

PREOPERATIVE

Patient Evaluation

Demonstration of lateral vaginal wall defects on physical examination is required prior to surgery. If significant anterior wall prolapse is identified, evaluation for SUI or occult SUI is pursued. In women who have a paravaginal defect, other pelvic support defects such as apical or posterior vaginal prolapse commonly coexist. Thus, attempts to identify these defects precede surgery.

Consent

Paravaginal defect repair provides support to the lateral vaginal walls, but as with other prolapse procedures, long-term success rates may diminish with time. The procedure involves surgery in the space of Retzius, which has the potential for significant blood loss. In particular, risks of bleeding and bladder injury are generally greater in patients with prior space of Retzius surgery as dense adhesions between bladder and pubic bone are common. Inaccurate suture placement can result in injury to the bladder and/or ureters, although this is infrequent.

Patient Preparation

As with most abdominal urogynecologic surgeries, antibiotic prophylaxis is given to prevent wound infection (Table 39-6). Bowel preparation may be implemented at the surgeon’s discretion if additional procedures are planned. Thromboprophylaxis is given as outlined in Table 39-8.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

When performed in conjunction with apical or other repairs, this surgery is typically performed as an inpatient procedure under general anesthesia. Following administration of anesthesia, the patient is placed in low lithotomy position in booted support stirrups. Adequate exposure to the vagina is vital because a vaginal hand is used to elevate and dissect the paravaginal/paravesical space. The abdomen and vagina are surgically prepared, and a Foley catheter with a 10-mL balloon is inserted.

Abdominal Incision

A low transverse incision placed 1 to 2 cm cephalad to the symphysis pubis affords the best exposure to the space of Retzius. This procedure is typically done in conjunction with abdominal sacrocolpopexy, and the abdominal cavity is entered (Section 43-2). If performed in isolation or with a Burch colposuspension, entry into the peritoneal cavity is not necessary to open the space of Retzius.

Entering the Space of Retzius

After incision of the fascia, the rectus muscles are separated in the midline and retractors are used to hold them apart. To open the space of Retzius, the correct dissection plane lies directly behind the pubic bone, deep to the transversalis fascia but superficial to the peritoneum. Loose areolar tissue is gently dissected in a lateral-to-medial fashion with atraumatic forceps or scissors beginning immediately behind the pubic bone (Fig. 45-14.1). If the correct plane is entered, this avascular potential space opens easily and without significant hemorrhage. Small bleeding vessels within the loose areolar tissue are coagulated as encountered. If significant bleeding does occur, the wrong tissue plane has likely been entered. From prior surgery in this space, the bladder often adheres to the pubic bone and anterior abdominal wall and thus sharp dissection is indicated.

After the medial portion of the space of Retzius is opened, the obturator canal is identified bilaterally so that its associated vessels and nerve can be avoided. The canal is generally found 5 to 6 cm lateral from the pubic symphysis midline and 1 to 2 cm below the iliopectineal line. The ischial spine is then palpated 4 to 6 cm below and posterior to the obturator canal. The remainder of the paravaginal space is opened with gentle blunt dissection using a gauze sponge. This dissection is generally directed lateromedially, that is, from obturator fascia to lateral bladder border, to expose the ATFP and paravaginal tissue. To assist, a vaginal hand pushing up into the space creates a firm surface to dissect against. In addition, a malleable retractor gently displaces the bladder to the contralateral side.

Large paravaginal blood vessels are often noted along the lateral vaginal wall. Bleeding from these vessels can be controlled by upward pressure of the vaginal hand while hemostatic sutures are placed.

Identification of the Arcus Tendineus Fascia Pelvis

The ATFP runs along the pelvic sidewall between the pubic bone and the ischial spine as a white connective tissue condensation. In those with defects, it may be attenuated, torn in the middle, or completely avulsed from the sidewall. Even in these cases, the distal third of the ATFP is generally preserved and easily identified.

Placement of Paravaginal Sutures

One or two fingers of the surgeon’s nondominant hand are placed in the vagina to elevate the lateral vaginal wall on the planned side of defect repair. At the same time, a medium-sized malleable retractor is used to reflect the bladder medially and protect it and the ureter from inadvertent suture placement or entrapment.

Usually four to six interrupted 2-0 gauge permanent sutures placed approximately 1 cm apart are needed to obliterate the paravaginal defect. The ultimate suture line extends from the level of the ischial spine to the level of the bladder neck or proximal urethra (Fig. 45-14.2). Each suture passes through the paravaginal tissue just lateral to the bladder wall and through the ATFP or obturator internus fascia and tied. A vaginal finger covered by a thimble for protection presses upward against the lateral vaginal wall to help isolate the paravaginal tissue and assess suture penetration. If a suture punctures the vaginal lumen, it is removed, discarded, and replaced by a more superficial stitch. If bleeding follows, the suture may be tied to constrict involved vessels. Prior to suture placement, the obturator canal and neurovascular bundle are identified and avoided. After all sutures are placed, the procedure is repeated on the other side of the vagina (Fig. 45-14.3).

Cystoscopy

This is performed to note efflux from both ureteral orifices and to exclude bladder-perforating sutures. A misplaced suture might be seen as a dimple in the bladder wall. If found, sutures entering the bladder are removed abdominally and properly placed.

Incision Closure

After vigorous irrigation of the space of Retzius, the abdomen is closed in a standard fashion (Section 43-2). If the peritoneum was opened, closure is recommended to prevent small bowel adhesions in the space of Retzius.

POSTOPERATIVE

In general, recovery follows that associated with laparotomy or endoscopy and varies depending on concurrent surgeries and incision size. A voiding trial as described in Chapter 42 (is performed prior to hospital discharge.

Posterior colporrhaphy, also colloquially termed posterior repair, is traditionally used to repair prolapse of the posterior vaginal compartment. Specifically, posterior colporrhaphy techniques attempt to reinforce the fibromuscular tissue layer between the vagina and rectum to prevent prolapse of the rectum into the vaginal lumen. The tissue plicated in the midline is often reapproximated distally to the level of the hymen and here includes reapproximation of the perineal body tissue. This is especially important for women who display “perineal descent” during preoperative evaluation. Women with such poor perineal strength may often reinforce (or splint) the perineal body to aid defecation. For these women, perineorrhaphy is often carried out concurrently. Often, the posterior vaginal wall apex must also be suspended to obtain successful repair and prevent recurrence. The apex may be suspended vaginally to the uterosacral or sacrospinous ligament or abdominally to the anterior longitudinal ligament of the sacrum. Thus, a careful preoperative evaluation is essential to restore anatomy.

There are three current transvaginal repairs of posterior wall prolapse. First, traditional midline plication of levator ani muscles, also known as levator myorrhaphy or levatorplasty, plicates the puborectalis muscle in the midline (Francis, 1961). Second, midline vaginal wall plication without levator myorrhaphy brings together the vaginal wall muscularis and adventitial layers in the midline. Tissue previously referred to as “rectovaginal fascia” is in fact these muscularis and adventitial layers, as histologic studies of normal anatomy illustrate a lack of true fascia between the vagina and rectum. Last, defect-directed, also called site-specific, repair reapproximates attenuated vaginal wall at specific bulge sites rather than rotely in the midline. Among these, evidence suggests that midline plication without levator myorrhaphy has superior objective outcomes compared with site-specific repair and has lower dyspareunia rates than levator myorrhaphy (Karram, 2013). For these reasons, midline plication without levator myorrhaphy is the procedure of choice for posterior compartment prolapse except perhaps in select cases, such as women with large genital hiatus undergoing colpocleisis.

Importantly, compared with these methods, a biologic or synthetic graft in the posterior compartment does not improve anatomic or functional outcomes (Maher, 2013; Paraiso, 2006; Sung, 2012). Well-designed studies that demonstrate efficacy and safety of newly developed grafts are needed before surgeons incorporate these materials into their practices.

PREOPERATIVE

Patient Evaluation

A detailed discussion of symptoms begins every patient evaluation prior to colporrhaphy. Often, patients may associate all of their bowel symptoms to a posterior wall bulge, but the two may not be related. Specifically, if constipation is a major complaint, further evaluation and trial of nonsurgical treatment is typically indicated (Chap. 25). Symptoms most likely to be cured or improved by posterior repair include the sensation of vaginal bulge and the need to digitally compress the rectal vault for defecation. Also termed vaginal splinting, compression involves placing fingers in the vagina and pushing downward over the defect or sweeping forward to help empty bowel. As another compensatory action, a digit may be inserted in the rectum to scoop out stool.

Posterior wall prolapse commonly accompanies other support defects, and patients undergo a complete pelvic organ prolapse examination. If concurrent anterior vaginal wall or vaginal apex prolapse is present, these are also repaired.

Consent

In addition to standard surgical risks, this procedure may be associated with failure to correct symptoms or anatomy. Accordingly, a patient and surgeon identify treatment goals and clarify expectations. In the few completed randomized studies, current techniques give a less than optimal anatomic repair, and success rates approximate 70 percent. Another frequent postoperative risk is dyspareunia, which is more common following the levator ani muscle plication discussed earlier. Accordingly, levator plication is not recommended in women who desire to preserve coital function. Injury to the rectum or rectovaginal fistula is another rare but potential complication.

Patient Preparation

Depending on surgeon preference, patients may be instructed to take in only clear liquids the day prior to surgery and complete one or two enemas that night or the morning of surgery. Ballard and associates (2014), however, noted no distinct advantage to this. Antibiotics and thromboprophylaxis are given as outlined in Tables 39-6 and 39-8.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

If done in isolation, posterior colporrhaphy is typically a day-surgery procedure for healthy women and performed under general or regional anesthesia. A patient is placed in standard lithotomy position in candy-cane or booted support stirrups. The vagina is surgically prepared, and a Foley catheter inserted.

Concurrent Surgery

Posterior colporrhaphy can be performed with the uterus in situ or alternatively, following hysterectomy. If other reconstructive surgeries are required, they may precede or follow posterior colporrhaphy. Notably, completion of the posterior repair prior to vaginal apex suspension permits the plicated and thus more substantial tissue to be anchored to selected ligaments during apical suspension.

Vaginal Incision and Dissection

Two Allis clamps are placed on the posterolateral wall of the distal vagina on either side of the midline. Clamps are gently pulled laterally to create tension, and the vaginal wall between them is incised transversely at or just proximal to the level of the hymen and superficial to the perineal body. A third Allis clamp is placed in midline and 3 to 4 cm proximal to the introitus. All three clamps are held, creating gentle outward tension. Metzenbaum scissors tips are insinuated beneath the epithelium in the midline of the previously made transverse incision and directed cephalad (Fig. 45-15.1). Scissor blades are opened and closed, while the surgeon exerts gentle forward pressure that is parallel to and within the plane beneath the vaginal epithelium. This technique allows separation of the epithelium from the fibromuscular layer. This dissection continues cephalad to reach the proximal midline Allis clamp. The undermined vaginal epithelium is then incised in the midline longitudinally.

The midline Allis clamp is then replaced further cephalad, and the process continues until the vaginal epithelium has been divided to the level of the vaginal apex. If a concurrent hysterectomy has been performed, the colporrhaphy incision generally extends to the cuff incision. In either case, if only a simple discrete distal to mid-vagina defect is present, then the midline colporrhaphy incision stops just cephalad to that defect’s proximal border.

Lateral Dissection

Along the freed epithelial edges, additional Allis or Allis-Adair clamps are placed to create gentle outward tension, while the vaginal epithelium is dissected laterally off the vagina’s fibromuscular wall. This is accomplished with one finger placed behind the epithelium to accentuate the dissection plane. Scissors are held parallel to the vagina and cut connective tissue fibers between the epithelium and fibromuscular layer.

During this early lateral dissection, the perineal body is fused with the vaginal wall fibromuscular layer, and scarring may be present from prior episiotomy. Thus, clear tissue planes are not typically present, and sharp dissection is required. Cephalad to the perineal body, once the desired tissue plane is entered, a combination of sharp and blunt dissection readily separates the layers. Simultaneous countertraction on the fibromuscular tissue by an assistant using tissue forceps or a gauze-covered finger can aid dissection. Separation in the correct tissue plane is essential. Deep dissection can enter rectum, whereas superficial dissection can create holes in the vaginal epithelium, often called “button holes.”

This tissue separation is extended laterally toward the pelvic walls until substantial fibromuscular tissue is exposed to permit midline plication. The steps are then repeated on the contralateral side.

Rectal Examination

Rectal examination is performed to exclude rectal injury and to help identify the edges of the fibromuscular wall to be plicated (Fig. 45-15.2).

Midline Plication

A series of interrupted 2-0 gauge delayed-absorbable sutures are used to plicate the vaginal muscularis and perineal body tissue along the length of the posterior vaginal wall (Figs. 45-15.3 and 45-15.4). As noted, levator plication is avoided in patients who desire to preserve coital function as the risks of vaginal lumen narrowing and dyspareunia may be higher. To plicate tissue, an interrupted stitch of 2-0 gauge delayed-absorbable suture is placed on one side of the midline beginning nearest the apex. This same needle and suture are carried to the other side of the midline, and a mirror stitch is placed the same distance from the apex. The the bites of each stitch are generously spaced to bring together the wide lateral span of attenuated tissue. Such plication creates a firm fibromuscular wall layer to support the rectum and if indicated, the perineal body. However, excessive tension is avoided to prevent sutures from pulling through the fibromuscular tissue or from significantly narrowing the vagina. As sutures are tied, the midline rectal bulge is gently pushed downward by the surgeon and away from the incision line.

Rectal examination is again performed after all sutures are placed to exclude inadvertent suture placement into the rectum. If identified, these are removed and correct suture placement completed.

Defect Assessment

In some instances, a discrete defect is identified in the posterior fibromuscular layer after the initial dissection. Defects may be lateral, midline, apical, or perineal (Figs. 45-15.5 and 45-15.6). Repair focuses solely on the defect, which is closed by interrupted stitches of 2-0 gauge delayed-absorbable sutures. This is generally a one-layer closure. This repair may be complemented by a midline plication if significant tissue attenuation is still noted.

Indicated Apical Suspension

If indicated, apical suspension is performed after vaginal wall plication. The proximal posterior vagina is affixed to either the uterosacral or sacrospinous ligament, as described on page 1107. If perineorrhaphy is planned, it is also completed prior to incision closure.

9 Incision Closure

Following plication, redundant vaginal wall often remains and requires trimming. Liberal trimming, however, can narrow the vagina and can place the vaginal wall incision on excessive tension that impairs wound healing. The vaginal mucosa is reapproximated in a running fashion using a 2-0 gauge delayed-absorbable suture. Widely positioned sutures are avoided as they can create accordion-type bunching of the vaginal epithelium and subsequent vaginal shortening when the final suture is tied.

POSTOPERATIVE

Patients are instructed on perineal hygiene. Constipation and straining are avoided, and stool softeners are usually prescribed. As with other vaginal surgery, diet and activity can be advanced as tolerated. Women, however, abstain from intercourse until wound healing is complete, typically at 6 to 8 weeks following repair. Some women have urinary retention after posterior repairs, even without an antiincontinence procedure. If unable to void spontaneously by the time of discharge, a patient can go home with a catheter and be seen again within a week for removal.

The perineal body serves as core support of the distal vagina, rectum, and pelvic floor. Therefore, a damaged or weakened perineal body may contribute to distal prolapse. Reinforcement of this structure, that is, perineorrhaphy, is often performed in conjunction with other reconstructive procedures, such as posterior colporrhaphy. To reestablish distal support, perineorrhaphy lengthens the anteroposterior dimension of a shortened perineal body, while the genital hiatus is concurrently narrowed.

PREOPERATIVE

Patient Evaluation

During assessment, the length of the genital hiatus is measured in centimeters both at rest and with Valsalva maneuver from the external urethral opening at 12 o’clock to the posterior aspect of the hymeneal ring at 6 o’clock. The perineal body is measured from the hymeneal ring at 6 o’clock to the mid-anus.

With perineorrhaphy planning, the degree to which the perineal body is lengthened can be tailored according patient symptoms, surgical goals, and clinical findings. With typical perineorrhaphy, the degree of perineal body lengthening is minimized to create or maintain a genital hiatus wide enough to preserve comfortable intercourse. Moreover, in sexually active postmenopausal women whose partners have decreased erectile tone, entry into the vagina may be difficult if the introitus is too narrow. Thus, following perineorrhaphy, 2 to 3 fingers ideally comfortably pass through the introitus.

For women with “perineal descent” who have to splint to defecate or in those with distal defects and attenuated perineal body tissue, perineorrhaphy may be coupled with posterior colporrhaphy. As described on page 1093, the distal extent of the plicated rectovaginal wall can be reattached to the perineal body. This reestablishes continuity of connective tissue support in the posterior vaginal compartment.

In some women, pelvic support takes precedence, and coital function is also not desired. With “high” perineorrhaphy, the superior-to-inferior extent of the perineal body is lengthened and generally accompanied by plication of the levator ani muscle fascia at the superior aspect of the perineal body. The result of this extensive perineorrhaphy is a shorter genital hiatus length and narrower introitus and vaginal lumen. This may be an advantageous adjunct to colpocleisis. However, data showing improved colpocleisis outcomes by adding levator myorrhaphy are limited (Gutman, 2009).

Consent

A patient preparing for perineorrhaphy is counseled regarding risks of postoperative dyspareunia, prolapse recurrence, or wound complications, such as a stitch abscess. Bleeding from perineal skin tearing during intercourse may also result and require minor surgical revision.

Patient Preparation

Because of the surgical site’s close proximity to the anus and also because bowel injury is possible, antibiotic prophylaxis is administered prior to surgery to minimize wound infection risks (Table 39-6). Bowel preparation, which may employ clear liquid diet and enemas, mirrors that for posterior repair. Thromboprophylaxis is given as outlined in Table 39-8.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

Perineorrhaphy is typically performed under general or regional anesthesia, and this choice is often dictated by concurrent surgeries planned. The patient is placed in standard lithotomy position in candy-cane or booted support stirrups. A vaginal and rectal examination under anesthesia is again performed to assess the size of the perineal body and defects of the posterior vaginal wall, which may also require repair. The vagina is surgically prepared, and a Foley catheter inserted.

Concurrent Surgery

If concurrent surgeries have been included, perineorrhaphy is the final procedure in most cases.

Incision

To determine the approximate appearance of the final repair, Allis clamps are placed on the posterolateral walls of the vagina at or just proximal to the hymen. These are brought together in the midline and 2 or 3 fingers should easily pass through the intended genital hiatus. If the resulting opening is too narrow, both Allis clamps are moved closer to the midline, and the above steps are repeated. With this technique, a surgeon can judge the final size of the introitus and perineal body. Because scarring and retraction can develop, it is prudent to err on the side of leaving the genital hiatus larger rather than smaller. To begin, a diamond-shape incision is made with its cephalad tip extending 2 to 3 cm into the vagina and the caudal tip extending to a point approximately 2 cm above the anus.

Removal of Skin and Mucosa

For traction, Allis clamps are placed at each corner of the diamond. Metzenbaum scissors are used to excise the perineal skin and vaginal epithelium within the diamond away from the underlying tissue. During dissection, the scissor tips are held parallel to the perineal and vaginal tissues, respectively.

Sharp dissection must be performed over the perineal body. This area contains a normal condensation of tissue, and scarring may also be present. As a result, development of good tissue planes is often not possible. A dilute vasopressin solution may be injected to decrease bleeding from extensive venous sinuses that are typically encountered in this region from obstetric or vaginal delivery scars. Frequent rectal examination during dissection may be required to assess the amount of tissue present between the anal and vaginal epithelium to prevent entry into the rectum.

Suture Placement

One centimeter caudal to the hymeneal ring, a 0-gauge delayed-absorbable suture on a CT-1 needle is used to approximate the connective tissue surrounding the perineal muscles (bulbospongiosus and superficial transverse perineal muscles) in the midline. In suturing this tissue, a wide lateral bite is taken, and suture is directed first in an inward-to-outward and then outward-to-inward sequence (Fig. 45-16.1). This suture technique ultimately buries knots below the plicated muscles. However, initially, the first suture is held and not tied.

Downward traction is placed, and a second suture is placed approximately 1 cm cephalad. This suture ideally reapproximates the separated ends of the perineal membrane. As with the first, this suture is not tied. A third suture can be placed 1 cm further cephalad to this, if necessary. In a similar fashion, one to two stitches are placed 1 cm apart and caudad to the primary suture. These lower stitches plicate the connective tissue surrounding the superficial transverse perineal muscles and upper extent of the external anal sphincter muscle in the midline. The sutures are then progressively tied beginning with the lowermost. In some cases, a second, more superficial layer is placed in the perineal body for additional support.

Vaginal and Perineal Closure

Starting at the vaginal apex, the vaginal epithelium is closed in a running fashion using 2-0 gauge delayed-absorbable suture (Fig. 45-16.2). When creating a running suture line in the vagina, stitches are placed close together. If suture bites are placed far apart during epithelial closure, the vagina can be shortened.

The running suture reapproximates the hymeneal ring and then is brought into the perineal area. The same suture may be used in a running mattress method to reapproximate the subcutaneous tissue to the end of the incision, near the anus. The skin is then reapproximated in an interrupted or running fashion using 3-0 gauge delayed-absorbable suture.

POSTOPERATIVE

Patients are instructed on perineal hygiene. Constipation is avoided and stool softeners are usually prescribed. As with other vaginal surgery, diet and activity can be advanced as tolerated. Women, however, abstain from intercourse until wound healing is complete, typically at 6 to 8 weeks following repair. Some women have urinary retention after perineorrhaphy, even without an antiincontinence procedure. If unable to void spontaneously by the time of discharge, a patient can go home with a catheter and be seen again within a week for removal.

Abdominal sacrocolpopexy (ASC) using graft material is a widely accepted transabdominal prolapse operation, and many consider it the preferred procedure to correct advanced apical prolapse. Grafts of autologous, cadaveric, or synthetic materials may be used, but permanent (synthetic) mesh has the best success rate and is selected unless otherwise contraindicated (Culligan, 2005). The graft augments native tissue and suspends the upper third of the vagina to the anterior longitudinal ligament of the sacrum. In addition to correcting apical prolapse, the graft also covers proximal portions of the anterior and posterior vaginal walls. As such, ASC also corrects apical segment prolapse of the anterior vagina wall (“apical” or “transverse” cystoceles) and of the posterior vaginal wall (enteroceles and “high” rectoceles). A modification of the procedure, sacrocolpoperineopexy, is used if concomitant perineal descent is present and believed to contribute to patient symptoms (Cundiff, 1997).

One advantage to ASC is its durability, and long-term success rates for apical suspension approximate 90 percent. It may be used as a primary procedure or alternatively as a repeat surgery for patients with recurrences after other prolapse repair failures. In addition, ASC is often chosen for women believed to be at high risk for recurrence and for whom mesh would augment their own tissue. Examples include those with connective tissue disease, history of recurrent hernia, obesity, or chronically increased intraabdominal pressure such as chronic obstructive pulmonary disease or chronic constipation. Abdominal synthetic mesh aids durability, but its use is balanced against the potential for complications, as discussed later.

Although the vaginal apex can also be successfully suspended with vaginal approach procedures such as sacrospinous ligament fixation and uterosacral ligament suspension, ASC offers distinct advantages. First, ASC maintains or lengthens the vagina, in contrast to vaginal approaches, which may shorten it. Second, the use of synthetic “permanent” mesh with multiple attachment sites to the vagina has a very low risk of apical failure. Finally, unlike vaginal approaches, in which the vaginal apex is directly affixed to a structure such as the uterosacral or sacrospinous ligament, ASC repositions the vaginal apex to its nearly normal anatomic position using intervening graft material. Thus, the apex typically remains mobile, which possibly lowers dyspareunia rates.

Sacrocolpopexy can be performed by laparotomy, by conventional laparoscopy, and with robotic assistance. If minimally invasive surgery (MIS) is performed in the same manner as the open operation, similar results can be expected. However, only limited data are currently available on long-term success rates with these MIS approaches (Freeman, 2013; Maher, 2013; Paraiso, 2011).

PREOPERATIVE

Patient Evaluation

Prolapse of the vaginal apex often coexists with other prolapse sites along the vagina. Accordingly, a careful preoperative search is performed for other prolapse sites. If necessary, ASC can be completed concurrently with paravaginal defect repair, posterior repair, or other prolapse surgeries. Beer and Kuhn (2005) found that approximately 70 percent of ASC procedures were performed with other pelvic reconstructive operations. With the technique we describe, a concurrent enterocele will be repaired by the colpopexy, and other enterocele repairs are thus unnecessary.

Prior to ASC, patients with symptoms of urinary incontinence undergo simple or complex urodynamic testing to clarify the type of incontinence and determine if an antiincontinence procedure will be beneficial. For those with SUI, a concurrent antiincontinence operation is generally performed. Because prolapse correction can unmask occult SUI in some women, clinicians also test those without incontinence while manually reducing the prolapse. Last, apical suspension can predispose to later development of anterior vaginal wall prolapse and SUI. Thus, stress-continent women undergoing ASC may elect a prophylactic SUI procedure. To evaluate this practice, the CARE (Colpopexy After Reduction Efforts) trial found that continent women undergoing ASC plus a prophylactic urethropexy had a 2-year postoperative SUI incidence of 32 percent. Without preventive urethropexy, SUI rates following ASC were 45 percent (Brubaker, 2006, 2008). Importantly, adding an antiincontinence procedure decreases, but does not eliminate, the risk of later de novo SUI. At this time, it is unclear how best to extrapolate these findings to women who elect to have sacrocolpopexy and midurethral sling procedures.

Consent

Recurrent prolapse is common following any corrective surgery. Thus, a surgeon should be aware of recurrence rates quoted in the literature and his or her own personal rates. Although apical prolapse recurrence is infrequent, later prolapse of the anterior and posterior vaginal walls is more common. An extension of the CARE trial used a clinically based definition of anatomic failure. It showed that by 5 years, nearly one third of women met the composite definition of failure (Nygaard, 2013). However, 95 percent had no retreatment for their prolapse.

Mesh erosion develops in 2 to 10 percent of cases. It is generally found at the apex and occurs more often if hysterectomy is performed concurrent with ASC. Erosion may arise soon after surgery or years later (Beer, 2005; Nygaard, 2004, 2013). Many technical points described in the following steps aim to prevent this complication.

Patient Preparation

Bowel preparation will vary depending on surgeon preference. Patients can be instructed to take only clear liquids the day prior to surgery and complete one or two enemas that night or the morning of surgery. Alternatively, a mechanical bowel preparation using agents listed in Chapter 39 may be preferred. Ballard and associates (2014), however, noted no distinct advantage to this for urogynecologic operations. Antibiotics and thromboprophylaxis are given as outlined in Tables 39-6 and 39-8.

For postmenopausal women, vaginal estrogen cream use during the 6 to 8 weeks prior to surgery has been routinely recommended. Estrogen treatment is thought to enhance vascularity and thereby increase tissue strength and promote healing. Although this is logical and commonly practiced, no data suggest that preoperative vaginal estrogen cream decreases mesh erosion or prolapse recurrence rates.

INTRAOPERATIVE

Instruments and Materials

The upper vagina must be elevated and distended by a vaginal manipulator to allow adequate dissection and delineation of the vaginal wall fibromuscular layers for mesh placement. The manipulator may be a cylindrical Lucite rod or a large EEA (end-to-end anastomosis) sizer, which is present in most operating rooms and shown in Figure 46-21.4.

The ideal bridging material for this procedure is permanent, nonantigenic, easily cut or customized, and readily available. The ideal mesh has a large pore size to allow host tissue ingrowth, is monofilament to decrease bacterial adherence, and is flexible. Currently, polypropylene mesh is the most common synthetic graft used (American Urogynecologic Society, 2013, 2014b).

Surgical Steps

Anesthesia and Patient Positioning

Following administration of general anesthesia, the patient is positioned in a modified supine position with thighs parallel to the ground and legs in booted support stirrups. Correct positioning prevents nerve injury and allows access to the vagina for manipulation and examination, to the bladder for cystoscopy, and to the abdomen for proper self-retaining retractor placement. The buttocks are positioned at the table edge or slightly distal to allow full range of vaginal manipulator motion. The vagina and abdomen are surgically prepared, and a Foley catheter is inserted.

Incision

A vertical or transverse abdominal incision may be used, and selection is directed by a woman’s body habitus and by planned concurrent procedures. A Pfannenstiel incision generally provides adequate access to the sacrum and deep pelvis. If a Burch colposuspension, paravaginal defect repair, or other surgery in the space of Retzius is planned, then a low transverse incision that is positioned closer to the symphysis may be preferred.

Bowel Packing

A self-retaining retractor, preferably a Balfour type, is placed, and the bowel is packed up and out of the pelvis with moist laparotomy sponges. Bowel packing attempts to shift the sigmoid colon farther to the patient’s left, thereby permitting access to the midline and right aspects of the sacrum.

Concomitant Hysterectomy

Some data suggest that hysterectomy at the time of ASC leads to higher mesh erosion rates (Culligan, 2002; Griffis, 2006). To reduce erosion risks at the cuff, some surgeons advocate supracervical hysterectomy, theorizing that the cervical stump may act as a barrier to prevent ascending infection and erosion (McDermott, 2009). If a total abdominal hysterectomy is performed, the vaginal apex is closed with absorbable suture such as 0-gauge polyglactin 910 (Vicryl) in a running or interrupted fashion. A second imbricating layer using the same suture may be placed to reduce potential mesh erosion. Another preventive measure is avoiding mesh fixation near the cuff suture line. Specifically, a 1-cm margin from this suture line may avert early mesh erosion during the cuff’s healing phase.

Identification of Pelvic Anatomy

Important boundaries during presacral space dissection are identified beneath the peritoneum prior to the posterior peritoneal incision. These include the aortic bifurcation, iliac vessels, right ureter, right uterosacral ligament, medial border of the rectosigmoid colon, and sacral promontory, which is the upper anterior surface of the S1 vertebra. An understanding that the right ureter, right common iliac artery, and left common iliac vein all lie within 3 cm of the sacral promontory’s midline may lower rates of their injury during surgery in the presacral space (Good, 2013b; Wieslander, 2006). Moreover, both ureters are threatened during dissection of the bladder off the anterior vaginal wall and during suturing of the anterior mesh strip.

Peritoneal Incision

The rectosigmoid colon is gently retracted to the left with a malleable ribbon or similar retractor. The peritoneum overlying the sacral promontory, between the rectosigmoid colon’s medial border and the right ureter, is elevated with tissue forceps and incised sharply. The incision is extended caudally into the posterior cul-de-sac of Douglas. As the incision approaches the deeper portion of the cul-de-sac, it is kept between the medial border of the rectum and the right uterosacral ligament. A vaginal manipulator directed ventrally to create tension aids dissection. The incision may then be continued to the posterior vaginal wall and toward the vaginal apex.

Maintaining proper orientation is critical during this step as inadvertent deviation can cause ureteral or iliac vessel injury on the right, or colon injury on the left. Similarly, if the initial peritoneal incision is extended above the sacral promontory, the left common iliac vein should be identified and avoided. This vessel can lie less than 1 cm from the promontory and is generally difficult to visualize or palpate due to its absent pulsatility and decreased tone. Final closure of this peritoneal incision allows the mesh to lie retroperitoneally. This may lower the risk of bowel-to-mesh adhesions and of bowel obstruction from small-bowel loops entrapped below the bridging mesh strip.

Identification of Anterior Longitudinal Ligament

Following peritoneal incision, the loose connective tissue between the peritoneum and the sacrum is sharply and bluntly dissected to expose the anterior longitudinal ligament lying along the sacrum’s vertical midsection. Generally, this presacral space dissection is started at the promontory and continued 3 to 4 cm inferiorly to the upper extent of the S2 vertebra. Within the connective tissue of the presacral space, fibers of the superior hypogastric nerve plexus, right and left hypogastric nerves, and the inferior mesenteric and superior rectal artery and vein are embedded (Fig. 38-23). Of these, the right hypogastric nerve is the most common structure identified during dissection. Below the aortic bifurcation, this midline cordlike nerve courses laterally and at the lower sacral levels, reaches the right pelvic sidewall. Transection of this nerve is ideally avoided.

Also of seminal importance, the middle sacral vessels typically adhere to the anterior surface of the ligament. Once found in the area exposed for mesh attachment, middle sacral vessels can be avoided, ligated, or coagulated depending on surgeon’s preference and operative findings. The middle sacral vein also forms anastomoses with the lateral sacral veins that contribute to the sacral venous plexus. Vessels of this plexus can be extensive, especially in the lower part of the sacrum.

Presacral Space Hemorrhage

Careful exposure of the anterior longitudinal ligament and overlying vessels helps prevent bleeding during suture placement. Despite these efforts, laceration of the sacral venous plexus can lead to rapid and substantial blood loss, and several steps are critical to its control. First, pressure is applied immediately and held for several minutes. This may be particularly effective for venous bleeding. Sutures and clips may be useful, but tearing of small veins frequently worsens with suturing. Additionally, as vessels retract into the bone, isolation and ligation becomes difficult. Sterile thumbtacks directed through lacerated vessels and pushed into the sacrum can effectively compress such vessels. Unfortunately, these tacks are not routinely found in many operating rooms.

Alternatively, various topical hemostatic agents have been used to control bleeding refractory to these initial steps (Table 40-5). Of these, the fibrin sealant family allows conformation to irregular wounds, which is a distinct advantage for presacral space hemorrhage. In refractory cases, vascular surgery consultation may be prudent. Also, injury to the iliac vessels or aorta necessitates immediate consultation.

Sacral Suture Site Selection

To anchor the suspending mesh strips proximally, a surgeon must decide whether to place sutures through the anterior longitudinal ligament at higher or lower sacral levels. Suture placement at the S3 or S4 vertebral bodies increases the risk of sacral venous plexus laceration, and this practice has largely been abandoned. Suture placement above the sacral promontory risks left common iliac vein injury and penetration of the L5-S1 disc, which may lead to painful discitis or osteomyelitis (Good, 2013a; Wieslander, 2006). However, this disc is the most protuberant structure in the presacral space, and mesh is commonly affixed here, especially during the learning phase of ASC (Abernathy, 2012).

For correct sacral promontory identification, the steep angle of descent between L5 and S1 can be used. That said, even correct suture placement at S1 and the sacral promontory still risks middle sacral vessel laceration. However, at S1, the middle sacral vessels are visible and can be easily isolated and avoided or when necessary, clipped or coagulated. Additionally at S1, the anterior longitudinal ligament is thicker and stronger than at lower sacral levels (White, 2009). Affixing sutures here minimizes suture avulsion risks. Finally, attachment of the mesh at S1 may result in a more anatomic suspension of the vaginal apex (Balgobin, 2013).

For these reasons, we prefer to affix mesh to the anterior surface of S1, with the most cephalad suture placed at or just below the sacral promontory. If safe suture placement over the S1 vertebra is prohibited, then the level of the L5-S1 disc is an alternative. Shallow tissue “bites” are needed here to avoid the disc as the anterior longitudinal ligament is only 1 to 2 mm thick.

Sacral Suture Placement

Typically, three or four serial permanent sutures are used to affix the sacral portion of mesh to the anterior longitudinal ligament. These stitches can be placed first, as described here, or later after vaginal mesh attachment. Needle passage moves from right to left with each stitch, and sutures are aligned vertically. Starting with the lowest suture, they are spaced approximately 0.5 to 1 cm apart. With suturing, 2-0 gauge permanent material, each double-armed with SH needles, is passed through the full thickness of the anterior longitudinal ligament (Fig. 45-17.1). During this, based on findings, suture “bites” either encompass or avoid vessels. Once completed, sutures are held by a hemostat and not tied. Their needles are covered with a surgical towel to avoid stick injuries.

Anterior Vaginal Wall Dissection

Prior to mesh attachment, the peritoneum and bladder must be dissected off the proximal vagina. Dissection of the bladder from the upper third of the anterior vaginal wall is aided by the vaginal manipulator. The cervical stump or vaginal apex is displaced cephalad and dorsally, and its covering peritoneum is incised transversely and proximal to the bladder’s cephalad margin. With prior hysterectomy, careful identification of the vaginal apex and superior extent of bladder is critical to avoid cystotomy. This is especially important in women with short vaginal lengths or vesicovaginal adhesions. In these cases, retrograde bladder filling and Foley bulb identification may help delineate the upper bladder margin. With cystotomy, several options are possible. If the cystotomy is small and close to the bladder dome, then a two- to three-layered bladder closure, followed by an interposition flap (omental or peritoneal), may be considered. However, if the cystotomy is large or nears the trigone, an alternative approach to vault suspension using native tissue may be considered to minimize mesh erosion into the bladder or fistula formation. Alternatively, the cystotomy can be repaired, and ASC deferred for a later time.

Once the correct vesicovaginal space is entered, the bladder is sharply dissected from the anterior vaginal wall for a distance of approximately 4 to 6 cm caudad to create an extensive surface for mesh fixation. However, the extent of this dissection varies depending on intraoperative anatomy. Sharp rather than blunt dissection is preferred in the vesicovaginal space (Fig. 45-17.2). Electrosurgical energy use is minimized to reduce risks of delayed thermal bladder injury. Dissection progresses at a depth above the fibromuscular layer of the vaginal wall. Entry into this proper plane lowers the rate of incidental entry into the vagina, which may increase future mesh erosion risks. If the vaginal lumen is entered, the opening is irrigated copiously and closed in two imbricated layers using 2-0 or 3-0 gauge delayed-absorbable suture.

Posterior Vaginal Wall Dissection

To expose an area of adequate size for mesh fixation, the rectovaginal space is entered, and the rectum is separated from the posterior vagina. For this, the vaginal manipulator now displaces the vaginal apex ventrally. The reflection of the rectum against the posterior vaginal wall is identified, and the peritoneum is incised transversely 2 to 3 cm proximal to this reflection line. The right and left uterosacral ligaments are used as lateral dissection boundaries. With gentle outward traction on the peritoneum, the rectovaginal space is developed with a combination of sharp and blunt dissection. In the absence of adhesions or fibrosis, the rectovaginal space easily opens inferiorly to the superior margin of the perineal body, which lies 3 to 4 cm above the hymen. Identification of loose gauzy connective tissue fibers usually indicates dissection in the correct plane. Also, the white, glistening posterior vaginal wall provides another visual clue, and dissection is kept close to this tissue to avoid inadvertent rectal entry. In contrast, fatty tissue or excessive bleeding generally indicates incorrect plane dissection and potential proximity to the rectum.

Graft Principles

Whether two separate strips of self-cut mesh or a commercially preformed Y-shaped mesh is used, several surgical principles are generally followed. First, depending on the extent of dissections, six to 12 sutures on the anterior and a similar number on the posterior vaginal wall are placed through the mesh and the vaginal wall muscularis. Sutures ideally do not enter the vaginal lumen because epithelial healing over the stitches may be incomplete, especially with braided suture. However, if the fibromuscular layer is thin, this may not be possible. In this setting, many select monofilament, delayed-absorbable suture, which has a greater propensity for epithelialization postoperatively.

Second, sutures are tied down loosely to avoid tissue strangulation and vaginal wall necrosis, which may lead to mesh or suture erosion. Third, the lower extent of the mesh does not abut the bladder or rectal reflections to minimize potential risks of pelvic organ dysfunction or mesh erosion of into these organs. Last, mesh is positioned symmetrically across the width of both the anterior and posterior vaginal walls.

At our institution, we fashion the two mesh strips only after vaginal dissection is completed. The broader area of each strip will cover the dissected anterior vaginal surface and posterior vaginal surface, respectively. Each strip also has a narrowed portion that will extend to the sacrum and be affixed to the anterior longitudinal ligament. This narrowed portion reduces mesh bulk, especially near the rectum on the left and the iliac vessels and ureter on the right, to lower mesh erosion rates. However, excessive narrowing may compromise overall repair strength (Balgobin, 2011). Generally, the narrow portion of mesh measures approximately 2 cm. Lengthwise, the proximal end of mesh is initially left long to allow correct positioning to the sacrum and later is trimmed.

Mesh Placement

To begin, the vaginal manipulator is pushed cephalad and ventrally to fully expose the dissected posterior vaginal wall and stabilize the vagina for suturing. The mesh is commonly attached to the posterior vaginal wall with two to four rows of 2-0 gauge permanent or delayed-absorbable sutures, and rows are placed approximately 1.5 cm apart (Fig. 45-17.3). Depending on the vaginal width and the lateral extent of dissection, each row consists of two to three sutures spaced 1 to 1.5 cm apart. The inferior and lateral extents of the dissected vagina are adequately exposed prior to suture placement to avoid incorporation of rectum into a stitch.

For the anterior vaginal wall, mesh is sutured in exactly the same fashion as was performed on the posterior wall (Fig. 45-17.4).

Mesh Sizing and Sacral Attachment

For this step, the prior sacral dissection is again exposed, and the two proximal portions of each mesh strip are held together by a right-angle clamp for maneuvering. The vaginal manipulator is removed and replaced by surgeon fingers. Then, by digital pressure directed cephalad, the cuff is gently elevated, and the proximal portions of mesh are extended to the earlier placed sacral sutures. Alternatively, the cuff can be gently elevated by the vaginal manipulator. With correct positioning, apical suspension reduces prolapse of the apex and the apical segments of the anterior and posterior vaginal walls. Moreover, the mesh segment between the vagina and sacrum should be tension free. Once the desired mesh position and length are determined, the excess mesh above the most cephalad sacral suture is trimmed off. This avoids mesh contact with the right ureter, iliac vein, and other vascular structures that all lie within 1 to 2 cm of the fixation site (Kohli, 1998; Nygaard, 2004).

The six needles of the three double-armed sacral sutures are then passed through the proximal portions of both mesh strips (Fig. 45-17.5). Each of the three sutures is then tied to secure the proximal mesh to the anterior longitudinal ligament (Fig. 45-17.6). To prevent air knots while the lowest sacral suture is secured, the surgeon gently pushes the vaginal apex against the lower part of the sacrum with the vaginal manipulator.

Peritoneal Closure

Reapproximation of the peritoneum over the mesh can be accomplished in a running or interrupted fashion using 3-0 or 2-0 gauge absorbable suture (Fig. 45-17.7). Placing this mesh retroperitoneally theoretically may lower the risk of bowel obstruction, but this complication has been reported despite peritoneal reapproximation (Pilsgaard, 1999). During closure, the right ureter is kept in constant view to avoid kinking or direct injury.

Cystoscopy

Cystoscopy is routinely performed prior to laparotomy closure to document ureteral integrity and absence of bladder sutures or injury. Urethral examination is important if an antiincontinence procedure is also performed.

Abdominal Closure

The abdomen is closed in a standard fashion (Section 43-1 or 43-2).

POSTOPERATIVE

Patient Care

Postoperative in-hospital management is similar to that for other intraabdominal surgeries. Specific to ASC, a passive or active voiding trial can be performed on postoperative day 1 or 2, depending on the patient’s condition and extent of dissection. Some women have urinary retention after apical suspension, even without an antiincontinence procedure. If unable to void spontaneously by the time of discharge, a patient can go home with a catheter and be seen again within a week for removal. A stool softener is prescribed when regular diet is tolerated, and constipation and straining are ideally avoided.

At routine postoperative visits, the patient is evaluated for prolapse recurrence and mesh or suture erosion. Symptoms of pelvic floor dysfunction are also elicited. Anatomic success does not always correlate with functional success, and vice versa. Thus, continual evaluation of surgical results is based on anatomy and on symptoms such as urinary incontinence, defecatory dysfunction, pelvic pain, and sexual dysfunction.

Complications

Following ASC, the graft material or its attaching sutures can erode through the vaginal epithelium. On average, symptoms develop 14 months following surgery, and vaginal bleeding and discharge are classic symptoms (Kohli, 1998). The diagnosis is generally straightforward, as mesh or sutures can be seen directly during speculum examination.

Mesh erosion through the vaginal mucosa may initially be treated with a 6-week or longer course of intravaginal estrogen cream. For those with exposed mesh and symptoms, surgical removal in an operating suite may be performed vaginally. Epithelium around the erosion site is sharply dissected from the mesh and undermined. The mesh is grasped, placed on gentle tension, dissected off the overlying tissue, and as much mesh as can be identified is resected. The vaginal epithelial edges are then trimmed to freshen edges and reapproximated in a running or interrupted fashion using 2-0 gauge delayed-absorbable suture. Failure of these wounds to heal is interpreted as a sign of graft or tissue infection, and more extensive or complete removal of the graft is considered. Sutures that are eroding into the vagina may be cut and removed in the office. Fortunately, removal of sutures or portions of eroding mesh does not generally compromise prolapse correction.

Sacrocolpopexy (SC) is increasingly being performed with a minimally invasive approach using conventional laparoscopy or robot-assisted laparoscopy. The basic procedural steps are the same as for laparotomic ASC and differ mainly by abdominal entry method and instruments used. Steps are outlined here, but a fuller discussion is found in Section 45-17.

Although not as extensively studied as abdominal sacrocolpopexy (ASC), limited data suggest that minimally invasive SC has similar short-term functional and anatomic results, shorter hospitalization, but longer operating times and greater cost (Judd, 2010; Siddiqui, 2012). Several randomized trials have compared outcomes and costs of laparoscopic sacrocolpopexy (LSC) with robotic sacrocolpopexy (RSC) (Anger, 2014; Paraiso, 2011). Compared with LSC, RSC carries increased cost, operative time, and higher pain scores, but short-term anatomic and functional outcomes and complications are similar. Data also show a longer robotic learning curve to achieve proficiency. That said, as robotic technology and training continues to develop, operative time, costs, and complications will likely decline.

PREOPERATIVE

Patient Evaluation

Candidates for minimally invasive SC undergo the same prolapse and incontinence evaluation as for ASC. As discussed in Chapter 41, factors influencing approach include patient overall health, restrictions to prolonged anesthesia, body habitus, intraabdominal adhesions, and surgeon skill.

Consent

Consent considerations mirror those for ASC. Additionally, with the minimally invasive approach, patients are counseled and consented for laparotomy if surgery cannot be completed by MIS. In addition, complications more common to laparoscopy are discussed (Chap. 41). These include puncture injury to organs and vessels during abdominal entry, positioning neuropathies, and delayed thermal injury to intraabdominal organs from electrosurgical tools.

Patient Preparation

This mirrors preparation for ASC and covers antibiotics and thromboembolism prophylaxis and bowel preparation options.

INTRAOPERATIVE

Surgical Steps

Anesthesia and Patient Positioning

Following administration of general anesthesia, the patient is positioned for laparoscopy in booted support stirrups as fully described in Chapter 41. The buttocks are positioned slightly distal to the table edge to compensate for mild upward patient migration that often occurs in the steep Trendelenburg position needed for laparoscopy. Correct positioning decreases nerve injury rates, provides access to the vagina, and allows full rotation of vaginal manipulator and laparoscopic instruments. The vagina and abdomen are surgically prepared, and a Foley catheter is inserted.

Incision and Trocar Placement

A full description of minimally invasive entry is found in Chapter 41. For LSC, four ports are generally used (Fig. 45-18.1). A 10-mm umbilical port houses the laparoscope; one 5-mm port is placed subcostally and lateral to the rectus abdominis muscle on either side for tissue manipulation; and two 10-mm ports, one in each lower quadrant, allow needle-bearing sutures to be threaded into the abdomen. Knots are tied using an extracorporeal technique, illustrated in Chapter 41.

For RSC, five ports are placed in a shallow “W” formation. One 12-mm umbilical port houses the laparoscope; one 8- or 10-mm assistant port is placed subcostally lateral to the rectus abdominis muscle on the right; and three 8-mm robotic ports are positioned in bilateral lower quadrants, with two on the left and one on the right. We dock the robotic cart on the patient’s left to permit manipulation of the vagina. Knots are tied using intracorporeal knot-tying techniques.

Concomitant Hysterectomy

The same considerations described for ASC apply to minimally invasive SC. An additional concern with minimally invasive total hysterectomy is the use of electrosurgery to amputate the uterus and its potential for greater cuff dehiscence and mesh erosion rates (Chap. 44). Moreover, limited data currently suggest that total hysterectomy at the time of minimally invasive sacrocolpopexy significantly increases the mesh erosion risk (Tan-Kim, 2011). Accordingly, in appropriately selected patients, supracervical hysterectomy (SCH) is preferred. During the final steps of SCH, to prepare for subsequent sacrocolpopexy, the serosal edges of the cervix may be reapproximated over the exposed endocervical canal using three to five interrupted 2-0 or 0-gauge polyglactin 910 (Vicryl) sutures.

Pelvic Anatomy Delineation

To begin sacrocolpopexy, the bowel is gently swept out of the pelvis and above the pelvic brim. With LSC, the rectosigmoid epiploicae may be sutured to the left pelvic sidewall to aid presacral space visualization. With RSC, to accomplish the same goal, an atraumatic grasper used through the third robotic port gently displaces the rectosigmoid laterally. Next, the aortic bifurcation and iliac vessels are identified, and the sacral promontory is visualized and probed in the midline. With RSC, promontory palpation using conventional laparoscopic instruments prior to robot docking is important. This provides tactile anatomic information that is not obtainable robotically. Last, other structures and boundaries are identified as described for ASC.

Peritoneal Incision

The peritoneum overlying the sacral promontory in the midline is elevated with tissue forceps and incised sharply with endoscopic scissors (Fig. 45-18.2). The incision is extended caudally into the posterior cul-de-sac of Douglas and then to the vaginal apex (Fig. 45-18.3). Upward and outward traction on the right and left peritoneal edges aids with dissection. Monopolar energy delivered through the scissors is intermittently used for peritoneal dissection and to control small-vessel bleeding.

Anterior Longitudinal Ligament Identification

Following peritoneal incision, the loose connective tissue between the peritoneum and the sacrum is sharply and bluntly dissected to expose presacral space anatomy similar to that for ASC. Gentle dissection with scissors or atraumatic tissue forceps removes fat and areolar tissue from the sacrum. Beneath these tissues, the shiny white anterior longitudinal ligament is seen overlying the bone in the midline. A gauze sponge introduced through the assistant port or a laparoscopic Kittner can assist this dissection.

During dissection, significant hemorrhage can occur. To apply bleeding site pressure, a gauze sponge and atraumatic forceps can be introduced through an assist