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In this major second part of the book, the cardinal manifestations of neurologic disease are described. In order to understand the signs and symptoms created by disordered function of the nervous system, it is necessary to first describe the normal anatomy and physiology, as they pertain to disease. Each chapter, therefore, begins with a consideration of these basic facts, followed by the manner in which they are affected by disease states and give rise to observable changes such as weakness, incoordination, abnormal movements, sensory loss, and pain.

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