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Chapter 10. Diagnostic Testing

In raising the cutoff point for a screening test, which of the following is the likely result?

A. An increase in sensitivity

B. An increase in specificity

C. An increase in false positives

D. An increase in prevalence

E. An increase in lead time bias

If the screening test does not delay the time of death from a condition but makes survival appear longer because of earlier detection of disease, there is evidence of

A. confounding.

B. length-biased sampling.

C. lead time bias.

D. selection bias.

E. information bias.

A test with an LR+ of 15 can be said to provide evidence to

A. rule in the condition of interest.

B. rule out the condition of interest.

C. make an earlier diagnosis.

D. prolong survival after diagnosis.

E. detect slowly progressing forms of the condition of interest.

A specific diagnostic test is one that

A. has a high proportion of false-negative results.

B. has a low proportion of false-negative results.

C. has a high proportion of false-positive results.

D. has a low proportion of false-positive results.

E. none of the above.

A diagnostic test with no discriminatory ability would have an area under the ROC curve of

A. 0.

B. 0.25.

C. 0.5.

D. 1.

E. 2.

A diagnostic test with an LR- of 0.05 can be said to provide evidence to

A. rule in the condition of interest.

B. rule out the condition of interest.

C. make an earlier diagnosis.

D. prolong survival after diagnosis.

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