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Hematological Disorders

A hemoglobin concentration below which of the following thresholds would indicate anemia in an iron-supplemented pregnant woman in any trimester?

a. 9.0 g/dL

b. 9.5 g/dL

c. 10.0 g/dL

d. 10.5 g/dL

What is the most common cause of antepartum anemia in pregnant women?

a. Thalassemia

b. Iron deficiency

c. Folic acid deficiency

d. Anemia of chronic disease

A 19-year-old primigravida at 29 weeks’ gestation is noted to have anemia with a hemoglobin concentration of 8 g/dL. The peripheral blood smear below is obtained. Which of the following laboratory findings are likely to accompany this condition?

Reproduced with permission from Beutler E: Disorders of iron metabolism. In Lichtman MA, Kipps TJ, Seligsohn U (eds): Williams Hematology, 8th ed. New York, McGraw-Hill, 2010, Figure 42-10C.

a. Decreased serum ferritin level

b. Elevated mean corpuscular volume

c. Decreased total iron binding capacity

d. Positive sickle-cell screen (Sickledex) result

A 19-year-old primigravida at 29 weeks’ gestation is noted to have anemia with a hemoglobin concentration of 8 g/dL. The peripheral blood smear below is obtained. For the patient, what is the most appropriate initial treatment?

Reproduced with permission from Beutler E: Disorders of iron metabolism. In Lichtman MA, Kipps TJ, Seligsohn U (eds): Williams Hematology, 8th ed. New York, McGraw-Hill, 2010, Figure 42-10C.

a. Red cell transfusion

b. Folic acid, 4 mg orally daily

c. Hydroxyurea, 1 g orally daily

d. Elemental iron, 200 mg orally daily

Of medical conditions associated with anemia of chronic disease, which is most frequently encountered in pregnancy?

a. Crohn disease

b. Hodgkin lymphoma

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