Chapter 20: Gestational Trophoblastic Disease

Gestational Trophoblastic Disease

As a group, gestational trophoblastic disease is typified by which of the following?

a. Scant cytotrophoblast

b. Perivillous fibrin deposition

c. Villous mesenchymal hyperplasia

d. Abnormal trophoblast proliferation

d. Introduction

As illustrated by differences seen here between invasive mole (A) and choriocarcinoma (B), hydatidiform moles as a group are differentiated histologically from other nonmolar neoplasms by the presence of which of the following?

a. Villi

b. Cytotrophoblast

c. Syncytiotrophoblast

d. Marked angiogenesis

a. Introduction

Gestational trophoblastic neoplasia includes all EXCEPT which of the following?

a. Invasive mole

b. Choriocarcinoma

c. Partial hydatidiform mole

d. Placental site trophoblastic tumor

c. Introduction

Which of the following histological changes, as shown here, are characteristic of hydatidiform moles?

a. Chronic villitis and villous inclusion bodies

b. Villous mesenchymal hyperplasia and acute villitis

c. Villous lymphocytic infiltrates and syncytial knots

d. Trophoblast proliferation and villous stromal edema

d. Hydatidiform Mole—Molar Pregnancy

A predominant maternal risk factor for molar pregnancy includes which of the following?

a. Advanced maternal age

b. Prior cesarean delivery

c. Type 2 diabetes mellitus

d. African American ethnicity

a. Epidemiology and Risk Factors...