... Table 36–5 Temperature–sensitive Mutants of Influenza Virus Used in Vaccine Type of Influenza Virus Growth in Nose (32°C) Growth in Lungs (37°C) Normal infectious virus Yes Yes Temperature–sensitive mutant used in vaccine Yes No ...
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... Table 30–1 Temperature-Sensitive Mutants of Influenza Virus Used in Vaccine Type of Influenza Virus Growth in Nose (32°C) Growth in Lungs (37°C) Normal infectious virus Yes Yes Temperature-sensitive mutant used in vaccine Yes No ...
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... Table 30–1 Temperature-Sensitive Mutants of Influenza Virus Used in Vaccine Type of Influenza Virus Growth in Nose (32°C) Growth in Lungs (37°C) Normal infectious virus Yes Yes Temperature-sensitive mutant used in vaccine Yes No ...
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... Table 36–5 Temperature–sensitive Mutants of Influenza Virus Used in Vaccine Type of Influenza Virus Growth in Nose (32°C) Growth in Lungs (37°C) Normal infectious virus Yes Yes Temperature–sensitive mutant used in vaccine Yes No ...
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... Table 38–2 Properties of Respiratory Viruses Property Influenza Virus Parainfluenza Virus, Respiratory Syncytial Virus, and Human Metapneumovirus Coronavirus Rhinovirus Adenovirus Virus family Orthomyxovirus Paramyxovirus...
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.... Influenza A virus is the main cause of worldwide epidemics (pandemics) of influenza. Characteristics —Enveloped virus with a helical nucleocapsid and segmented, single-stranded RNA of negative polarity. RNA polymerase in virion. The two major antigens are the hemagglutinin (HA) and the neuraminidase...
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.... Influenza A virus is the main cause of worldwide epidemics (pandemics) of influenza. Characteristics —Enveloped virus with a helical nucleocapsid and segmented, single-stranded RNA of negative polarity. RNA polymerase in virion. The two major antigens are the hemagglutinin (HA) and the neuraminidase...
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... In 2013, an outbreak of influenza caused by an H7N9 strain of influenza virus A in humans occurred. Prior to this time, the H7N9 strain affected only birds, especially chickens. Annual outbreaks have occurred, up to and including 2017. A total of 1258 infections in humans have been documented...
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... PCR technology has yielded gene fragments of influenza virus from archival lung tissue specimens from victims of the 1918 Spanish flu epidemic. The complete coding sequences of all eight viral RNA segments have been determined, and the sequences document that it was an H1N1 influenza A virus...
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... TABLE 38–2 Properties of Respiratory Viruses Property Influenza Virus Parainfluenza Virus, Respiratory Syncytial Virus, and Human Metapneumovirus Coronavirus Rhinovirus Adenovirus Virus family Orthomyxovirus Paramyxovirus Coronavirus...
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... In 1997, the H5N1 strain of influenza A virus that causes avian influenza , primarily in chickens, caused an aggressive form of human influenza with high mortality in Hong Kong. In the winter of 2003–2004, an outbreak of avian influenza caused by H5N1 strain killed thousands of chickens...
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... FIGURE 39-4 Schematic diagram of the life cycle of influenza virus. After receptor-mediated endocytosis, the viral ribonucleoprotein complexes are released into the cytoplasm and transported to the nucleus, where replication and transcription take place (1). Messenger RNAs are exported...
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... TABLE 39-3 Comparison of Viruses That Infect the Human Respiratory Tract Virus Disease Number of Serotypes Lifelong Immunity to Disease Vaccine Available Viral Latency RNA virusesInfluenza A virus Influenza Many...
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... Inactivated influenza vaccine is contraindicated in individuals with a severe allergic reaction, such as anaphylaxis, to a previous dose of an inactivated influenza vaccine component. However, guidelines for influenza vaccination in children with egg allergies have recently changed. Children...
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... Because influenza can circulate from November through early March in the US states, the optimal time to initiate vaccination is as soon as vaccine is available in the early fall. However, providers should continue vaccinating individuals as long as vaccine is available, and there is influenza...
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... In April 2009, a novel swine origin strain of influenza A (H1N1) virus (S-OIV) caused an outbreak of human influenza, which appeared first in Mexico, then in the United States, followed by spread to 208 countries by December 2009. The Centers for Disease Control and Prevention (CDC) uses...
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... Injection site reactions are the most common adverse events after inactivated influenza vaccine administration. A small proportion of children will experience some systemic toxicity, consisting of fever, malaise, and myalgias. These symptoms generally begin 6–12 hours after vaccination and may...
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