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Disorders of Bone and Calcium Homeostasis

AUTHOR:
Joseph Mort
LEARNING OBJECTIVES:
  1. Understand the regulation of calcium homeostasis including the role of parathyroid hormone, cholecalciferol, and calcitonin.
  2. Recognize the symptoms of hypercalcemia and hypocalcemia and list possible causes.
  3. Differentiate between primary, secondary, and tertiary hyperparathyroidism by the underlying mechanism and levels of calcium, phosphate, PTH, and vitamin D.
  4. Identify the clinical features of hypoparathyroidism.
  5. List risk factors for vitamin D deficiency and recognize the typical clinical features for both children and adults.
  6. Explain how osteoporosis is defined and know screening recommendations, risk factors, and potential complications of this disorder.
  7. Be familiar with medications used for the treatment of osteoporosis.
  8. Identify the pathogenesis and clinical features of Paget’s disease of the bone and potential complications.
Section
AccessMedicine > Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine > Management of Complications Associated with Advanced CKD/ESRD > Bone mineral metabolism
Section
AccessMedicine > Huppert’s Notes: Pathophysiology and Clinical Pearls for Internal Medicine > Diseases & Pathophysiology in General Medicine > OSTEOPOROSIS
Chapter
AccessMedicine > Harrison's Principles of Internal Medicine, 21e > Osteoporosis
Chapter
AccessMedicine > Current Medical Diagnosis & Treatment 2024 > Osteoporosis
Case File
AccessMedicine > Case Files: Physiology 2e > Case 38 > Calcium Metabolism
Case File
AccessMedicine > Case Files: Internal Medicine 6e > Case 35 > Osteoporosis, Cushing Syndrome
Case File
AccessMedicine > Pathophysiology of Disease Cases > Case 89 > Primary Hyperparathyroidism
Case File
AccessMedicine > Pathophysiology of Disease Cases > Case 92 > Hypoparathyroidism and Pseudohypoparathyroidism
Case File
AccessMedicine > Pathophysiology of Disease Cases > Case 94 > Osteoporosis
Case File
AccessMedicine > Vanderbilt Internal Medicine and Pediatric Curriculum > 26 > Osteopenia and Osteoporosis
Section
AccessMedicine > The Infographic Guide to Medicine > Endocrinology > Hypercalcemia and Hyperparathyroidism
Section
AccessMedicine > The Infographic Guide to Medicine > Endocrinology > Osteoporosis

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