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Clerkship Topics | Endocrinology:

Pituitary and Hypothalamic Disorders

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AUTHORS:
Joseph Mort
LEARNING OBJECTIVES:
  1. Understand the hypothalamic-pituitary axis, the hormones secreted from these glands, and the regulatory mechanisms that control hormone secretion.
  2. Identify the symptoms of hypopituitarism (affecting individual hormones and panhypopituitarism) and list possible causes of these disorders.
  3. Identify the symptoms of a pituitary mass lesion and list pathologies that cause mass lesions in the sella turcica.
  4. Recognize the typical presentation associated with overexpression of each of the following pituitary hormones (ACTH, growth hormone, TSH, LH/FSH, prolactin). 
  5. Understand how hormone levels at various levels of the hypothalamic-pituitary axis can be used to diagnose pathologies of over or under production (i.e. levels of CRH, ACTH, cortisol and the dexamethasone suppression test).
  6. Explain how dysfunction in secretion of antidiuretic hormone from the posterior pituitary leads to diabetes insipidus and syndrome of inappropriate antidiuretic hormone.
Section
AccessMedicine > Current Medical Diagnosis & Treatment 2019 > Endocrine Disorders > DISEASES OF THE HYPOTHALAMUS & PITUITARY GLAND
Required
Case File
AccessMedicine > Case Files: Internal Medicine 5e > Case 47 > Case
Required
Case File
AccessMedicine > Case Files: Internal Medicine 5e > Case 49 > Adrenal Insufficiency
Required
Case File
AccessMedicine > Pathophysiology of Disease Cases > Case 103 > Hypopituitarism
Required

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