RT Book, Section
A1 Armao, Diane
A1 Bouldin, Thomas
A2 Reisner, Howard M.
SR Print(0)
ID 1115282164
T1 Pathology of the Nervous System
T2 Pathology: A Modern Case Study
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071621564
LK accessmedicine.mhmedical.com/content.aspx?aid=1115282164
RD 2024/04/19
AB The  central  nervous  system  (CNS)  comprises  the  brain  and  spinal  cord  and  is  the  most  complex  organ  system  in  the  human  body.  The  CNS  differs  from  other  organ  systems  in  the  variety  of  functions  that  it  provides  and  in  the  localization  of  these  functions  to  specialized  areas  of  the  CNS.  The  localization  of  specialized  functions  means  that  a  relatively  small,  focal  lesion  in  the  CNS  can  produce  a  profound  deficit,  for  example,  loss  of  speech.  This  localization  also  results  in  the  various  populations  of  neurons  within  the  CNS  having  unique  capabilities  and  also  unique  vulnerabilities  to  disease.  For  example,  Parkinson  disease  (PD)  preferentially  affects  the  neurons  of  the  substantia  nigra  in  the  brain  stem,  while  Alzheimer  disease  (AD)  preferentially  affects  the  neurons  of  the  cerebral  cortex.