RT Book, Section
A1 Carroll, Karen C.
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 McKerrow, James H.
A1 Sakanari, Judy A.
SR Print(0)
ID 1114736918
T1 Hepatitis Viruses
T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071824989
LK accessmedicine.mhmedical.com/content.aspx?aid=1114736918
RD 2024/04/19
AB Viral  hepatitis  is  a  systemic  disease  primarily  involving  the  liver.  Most  cases  of  acute  viral  hepatitis  in  children  and  adults  are  caused  by  one  of  the  following  five  agents:  hepatitis  A  virus  (HAV),  the  etiologic  agent  of  viral  hepatitis  type  A  (infectious  hepatitis);  hepatitis  B  virus  (HBV),  which  is  associated  with  viral  hepatitis  B  (serum  hepatitis);  hepatitis  C  virus  (HCV),  the  agent  of  hepatitis  C  (common  cause  of  posttransfusion  hepatitis);  hepatitis  D  (HDV),  a  defective  virus  dependent  on  coinfection  with  HBV;  or  hepatitis  E  virus  (HEV),  the  agent  of  enterically  transmitted  hepatitis.  Additional  well-­characterized  viruses  that  can  cause  sporadic  hepatitis,  such  as  yellow  fever  virus,  cytomegalovirus,  Epstein-Barr  virus,  herpes  simplex  virus,  rubella  virus,  and  the  enteroviruses,  are  discussed  in  other  chapters.  Hepatitis  viruses  produce  acute  inflammation  of  the  liver,  resulting  in  a  clinical  illness  characterized  by  fever,  gastrointestinal  symptoms  such  as  nausea  and  vomiting,  and  jaundice.  Regardless  of  the  virus  type,  identical  histopathologic  lesions  are  observed  in  the  liver  ­during  acute  disease.