RT Book, Section A1 Carroll, Karen C. A1 Hobden, Jeffery A. A1 Miller, Steve A1 Morse, Stephen A. A1 Mietzner, Timothy A. A1 Detrick, Barbara A1 Mitchell, Thomas G. A1 McKerrow, James H. A1 Sakanari, Judy A. SR Print(0) ID 1114733638 T1 The Staphylococci T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071824989 LK accessmedicine.mhmedical.com/content.aspx?aid=1114733638 RD 2024/04/19 AB The staphylococci are gram-positive spherical cells, usually arranged in grapelike irregular clusters. They grow readily on many types of media and are active metabolically, fermenting carbohydrates and producing pigments that vary from white to deep yellow. Some are members of the normal microbiota of the skin and mucous membranes of humans; others cause suppuration, abscess formation, a variety of pyogenic infections, and even fatal septicemia. The pathogenic staphylococci often hemolyze blood, coagulate plasma, and produce a variety of extracellular enzymes and toxins. The most common type of food poisoning is caused by a heat-stable staphylococcal enterotoxin. Staphylococci rapidly develop resistance to many antimicrobial agents, which consequently presents difficult therapeutic problems.