RT Book, Section
A1 Carroll, Karen C.
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 McKerrow, James H.
A1 Sakanari, Judy A.
SR Print(0)
ID 1114733535
T1 Aerobic Non–Spore-Forming Gram-Positive Bacilli: Corynebacterium, Listeria, Erysipelothrix, Nocardia, and Related Pathogens
T2 Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071824989
LK accessmedicine.mhmedical.com/content.aspx?aid=1114733535
RD 2024/04/20
AB The  non–spore-forming  gram-positive  bacilli  are  a  diverse  group  of  aerobic  and  anaerobic  bacteria.  This  chapter  focuses  on  the  aerobic  members  of  this  group.  The  anaerobic,  non–spore-forming  gram-positive  bacilli  such  as  Propionibacterium  species  and  Actinomyces  species  are  discussed  in  Chapter  21  on  anaerobic  infections.  Specific  genera  of  both  groups,  namely,  Corynebacterium  species  and  Propionibacterium  species,  are  members  of  the  normal  microbiota  of  skin  and  mucous  membranes  of  humans  and,  as  such,  are  frequently  contaminants  of  clinical  specimens  submitted  for  diagnostic  evaluation.  However,  among  the  aerobic  gram-positive  bacilli  are  significant  pathogens  such  as  Corynebacterium  diphtheriae,  an  organism  that  produces  a  powerful  exotoxin  that  causes  diphtheria  in  humans,  and  Mycobacterium  tuberculosis  (see  Chapter  23),  the  causative  agent  of  tuberculosis.  Listeria  monocytogenes  and  Erysipelothrix  rhusiopathiae  are  primarily  found  in  animals  and  occasionally  cause  severe  disease  in  humans.  Nocardia  and  Rhodococcus  species  are  found  in  the  soil  and  are  significant  pathogens  among  immunocompromised  patients.