RT Book, Section A1 Doherty, Gerard M. A2 Doherty, Gerard M. SR Print(0) ID 1105489553 T1 Biliary Tract T2 CURRENT Diagnosis & Treatment: Surgery, 14e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071792110 LK accessmedicine.mhmedical.com/content.aspx?aid=1105489553 RD 2024/04/19 AB The anlage of the biliary ducts and liver consists of a diverticulum that appears on the ventral aspect of the foregut in 3 mm embryos. The cranial portion becomes the liver; a caudal bud forms the ventral pancreas; and an intermediate bud develops into the gallbladder. Originally hollow, the hepatic diverticulum becomes a solid mass of cells that later recanalizes to form the ducts. The smallest ducts—the bile canaliculi—first appear as a basal network between the primitive hepatocytes that eventually expands throughout the liver (Figure 25–1). Numerous microvilli increase the canalicular surface area. Bile secreted here passes through the interlobular ductules (canals of Hering) and the lobar ducts and then into the hepatic duct in the hilum. In most cases, the common hepatic duct is formed by the union of a single right and left duct, but in 25% of individuals, the anterior and posterior divisions of the right duct join the left duct separately. The origin of the common hepatic duct is close to the liver but always outside its substance. It runs about 4 cm before joining the cystic duct to form the common bile duct. The common duct begins in the hepatoduodenal ligament, passes behind the first portion of the duodenum, and runs in a groove on the posterior surface of the pancreas before entering the duodenum. Its terminal 1 cm is intimately adherent to the duodenal wall. The total length of the common duct is about 9 cm.