RT Book, Section A1 Holcroft, James W. A1 Anderson, John T. A1 Sena, Matthew J. A2 Doherty, Gerard M. SR Print(0) ID 1105485163 T1 Shock & Acute Pulmonary Failure in Surgical Patients T2 CURRENT Diagnosis & Treatment: Surgery, 14e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071792110 LK accessmedicine.mhmedical.com/content.aspx?aid=1105485163 RD 2024/04/19 AB Cardiovascular failure, or shock, can be caused by (1) depletion of the vascular volume; (2) compression of the heart or great veins; (3) intrinsic failure of the heart itself or failure arising from excessive hindrance to ventricular ejection; (4) loss of autonomic control of the vasculature; (5) severe untreated systemic inflammation; and (6) severe but partially compensated systemic inflammation. If the shock is decompensated, the mean blood pressure or the cardiac output (more precisely, the product of the pressure and output) will be inadequate for peripheral perfusion. In compensated shock, the perfusion will be adequate but only at the expense of excessive demands on the heart. Depending on the type and severity of cardiovascular failure and on response to treatment, shock can go on to compromise other organ systems. This chapter discusses the cardiovascular and pulmonary disorders associated with shock.