RT Book, Section
A1 Heist, Rebecca S.
A1 Sequist, Lecia V.
A2 Murray, Michael F.
A2 Babyatsky, Mark W.
A2 Giovanni, Monica A.
A2 Alkuraya, Fowzan S.
A2 Stewart, Douglas R.
SR Print(0)
ID 1102700449
T1 Lung Cancer
T2 Clinical Genomics: Practical Applications in Adult Patient Care
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 9780071622448
LK accessmedicine.mhmedical.com/content.aspx?aid=1102700449
RD 2024/04/23
AB Disease  summary:Lung  cancer  is  the  leading  cause  of  cancer  mortality  in  the  United  States.Approximately  85%  of  lung  cancers  are  nonsmall  cell  lung  cancer  (NSCLC),  and  about  15%  small  cell  lung  cancer  (SCLC).  Among  NSCLC,  the  incidence  of  adenocarcinoma  is  rising  to  surpass  that  of  squamous  cell  carcinoma.Presenting  symptoms  may  include  shortness  of  breath,  cough,  weight  loss,  or  symptoms  from  a  metastatic  site  such  as  headache  or  seizure  from  a  brain  metastasis  or  pain  from  a  bony  metastasis.  Clinical  symptoms  typically  present  late  in  the  course  of  disease  and  most  patients  are  diagnosed  with  advanced  lung  cancer.NSCLC  staging  uses  the  TNM  system,  in  which  T  stage  describes  tumor  size  and  location,  N  stage  describes  nodal  status,  and  M  stage  describes  metastases—the  overall  TNM  defines  if  the  cancer  is  stage  I,  II,  III,  or  IV.SCLC  is  staged  as  either  limited  stage  or  extensive  stage,  depending  on  the  extent  of  the  tumor  and  whether  it  can  fit  within  a  radiation  port  (limited)  or  not  (extensive).