RT Book, Section A1 Bush, Melissa C. A1 Pernoll, Martin L. A2 DeCherney, Alan H. A2 Nathan, Lauren A2 Laufer, Neri A2 Roman, Ashley S. SR Print(0) ID 56967022 T1 Chapter 17. Multiple Gestation T2 CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-163856-2 LK accessmedicine.mhmedical.com/content.aspx?aid=56967022 RD 2024/04/24 AB The incidence of multiple gestations has risen significantly over several decades, primarily due to increased use of fertility drugs for ovulation induction, superovulation, and assisted reproductive technologies (ART), such as in vitro fertilization (IVF).Compared with singleton pregnancies, twin pregnancies are more likely to be complicated by hypertensive disorders, gestational diabetes mellitus, anemia, preterm birth, ante- and postpartum hemorrhage, and maternal death.The perinatal mortality rate of twins is 3–4 times higher—and for triplets much higher still—than in singleton pregnancies as a result of chromosomal abnormalities, prematurity, structural anomalies, hypoxia, and trauma.This is particularly true of monozygotic twins, which are also uniquely susceptible to twin–twin transfusion syndrome.