RT Book, Section
A1 Trier, Jerry S.
A2 Greenberger, Norton J.
A2 Blumberg, Richard S.
A2 Burakoff, Robert
SR Print(0)
ID 55957611
T1 Chapter 20. Intestinal Malabsorption
T2 CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 2e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-176848-1
LK accessmedicine.mhmedical.com/content.aspx?aid=55957611
RD 2024/04/24
AB Celiac  disease—characteristic  though  not  specific  small  bowel  mucosal  lesion,  positive  anti–tissue  transglutaminase  test  (anti-tTGA)  or  antiendomysial  antibody  test  (anti-EMA),  and  clinical  response  to  gluten  withdrawal.Tropical  sprue—appropriate  geographic  exposure;  exclude  other  mucosal  diseases  (eg,  celiac  disease  and  protozoal  infections),  exclude  small  intestinal  bacterial  overgrowth,  and  assess  response  to  antibiotics  and  folate.Eosinophilic  gastroenteritis—histologic  demonstration  of  increased  gastric,  intestinal,  or  colonic  mucosal  or  mural  eosinophilic  infiltration  or  eosinophilic  ascites.Systemic  mastocytosis—demonstration  of  increased  mucosal  mast  cells  (>20  per  high-power  field)  in  stomach,  small  bowel,  colon;  elevated  serum  tryptase.Radiation  enteritis—history  of  radiation  with  mucosal  telangiectasias,  obliterative  endarteriolitis,  fibrosis,  and  strictures;  small  intestinal  bacterial  overgrowth  may  develop.Whipple  disease—demonstrate  Tropheryma  whipplei  and  characteristic  periodic  acid–Schiff-positive  macrophages  in  intestinal  mucosa  or  other  tissue.Small  intestinal  bacterial  overgrowth—document  evidence  of  malabsorption,  positive  breath  test  (lactulose,  glucose),  response  to  antibiotics.Short  bowel  syndrome—history  of  small  bowel  resection  and  confirmation  by  imaging  (barium  contrast  small  bowel  series  or  computed  tomographic  enterography).Intestinal  lymphangiectasia—hypoproteinemia,  lymphopenia,  evidence  of  protein-losing  enteropathy,  increased  fecal  loss  of  α1-antitrypsin.