RT Book, Section
A1 Dave, Chirag N.
A1 Burnett, Arthur L.
A1 Herati, Amin S.
A2 Bhasin, Shalender
A2 O’Leary, Michael P.
A2 Basaria, Shehzad S.
SR Print(0)
ID 1174514993
T1 Pathophysiology of Erectile Dysfunction
T2 Essentials of Men’s Health
YR 2021
FD 2021
PB McGraw Hill
PP New York, NY
SN 9781260135886
LK accessmedicine.mhmedical.com/content.aspx?aid=1174514993
RD 2024/04/19
AB Erectile  dysfunction  (ED)  refers  to  the  inability  to  achieve  or  maintain  an  erection  that  is  sufficient  for  satisfactory  intercourse.  It  is  multidimensional  and  can  arise  from  organic,  relational,  and/or  psychogenic  causes.1  The  Massachusetts  Male  Aging  Study  (MMAS)  reported  a  52%  prevalence  of  mild  to  moderate  ED  in  men  aged  40  to  70,  and  ED  was  found  to  be  associated  with  age,  health  status,  and  emotional  function.2,3  ED  has  detrimental  effects  on  partner  satisfaction  and  the  couple’s  quality  of  life.  It  was  previously  believed  that  most  ED  was  psychogenic;  however,  more  recent  evidence  shows  that  roughly  80%  of  ED  is  organic.3  ED  may  be  a  manifestation  of  endothelial  dysfunction.  Cardiovascular  disease,  poor  general  health  status,  diabetes,  smoking,  medications,  and  socioeconomic  status  are  well-established  risk  factors  for  ED.  Identification  of  these  comorbid  conditions  offers  the  men’s  health  provider  an  opportunity  to  diagnose  and  intervene  on  conditions  that  may  otherwise  be  asymptomatic.  This  chapter  includes  a  brief  discussion  of  the  physiology  of  erection  as  it  relates  to  a  more  complex  discussion  of  the  pathophysiology  of  ED.