RT Book, Section
A1 Riedel, Stefan
A1 Hobden, Jeffery A.
A1 Miller, Steve
A1 Morse, Stephen A.
A1 Mietzner, Timothy A.
A1 Detrick, Barbara
A1 Mitchell, Thomas G.
A1 Sakanari, Judy A.
A1 Hotez, Peter
A1 Mejia, Rojelio
SR Print(0)
ID 1163279121
T1 Pathogenesis of Bacterial Infection
T2 Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260012026
LK accessmedicine.mhmedical.com/content.aspx?aid=1163279121
RD 2024/04/20
AB The  pathogenesis  of  bacterial  infection  includes  initiation  of  the  infectious  process  and  the  mechanisms  that  lead  to  the  development  of  signs  and  symptoms  of  disease.  The  biochemical,  structural,  and  genetic  factors  that  play  important  roles  in  bacterial  pathogenesis  are  introduced  in  this  chapter  and  may  be  revisited  in  the  organism-specific  sections.  Characteristics  of  bacteria  that  are  pathogens  include  transmissibility,  adherence  to  host  cells,  persistence,  invasion  of  host  cells  and  tissues,  toxigenicity,  and  the  ability  to  evade  or  survive  the  host’s  immune  system.  Resistance  to  antimicrobials  and  disinfectants  can  also  contribute  to  virulence,  or  an  organism’s  capacity  to  cause  disease.  Many  infections  caused  by  bacteria  that  are  commonly  considered  to  be  pathogens  are  inapparent  or  asymptomatic.  Disease  occurs  if  the  bacteria  or  immunologic  reactions  to  their  presence  cause  sufficient  harm  to  the  person.