RT Book, Section A1 Johnston-MacAnanny, Erika B. A1 Patel, Bansari G. A1 Taylor, Robert N. A2 Hammer, Gary D. A2 McPhee, Stephen J. SR Print(0) ID 1156660478 T1 Disorders of the Female Reproductive Tract T2 Pathophysiology of Disease: An Introduction to Clinical Medicine, 8e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260026504 LK accessmedicine.mhmedical.com/content.aspx?aid=1156660478 RD 2024/04/19 AB Disorders of the female reproductive system can occur as a result of disease in one of the many reproductive organs: the ovaries, the fallopian tubes, the uterus, the cervix, the vagina, or the breast. During the reproductive years, these disorders often present as altered menstruation, pelvic pain, or infertility. Cancers arising in these tissues occur more often in the late reproductive or menopausal years. Unfortunately, for several reasons, they often have high mortality rates and a high incidence of metastases when diagnosed. Some organs are located deep and are relatively inaccessible to palpation (ovaries). Others have few sensory nerves (ovary, fallopian tubes) and hence remain asymptomatic. Additionally, the breasts have large amounts of adipose tissue, which can make early detection of breast cancer difficult. The one exception is the uterine cervix. Its easy access enables screening by use of the Papanicolaou smear and human papillomavirus (HPV) testing; this screening has led to a dramatically reduced mortality rate of cervical cancer.