RT Book, Section
A1 Lakdawala, Neal K.
A1 Stevenson, Lynne Warner
A1 Loscalzo, Joseph
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1156756234
T1 Cardiomyopathy and Myocarditis
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accessmedicine.mhmedical.com/content.aspx?aid=1156756234
RD 2024/04/19
AB Cardiomyopathy  is  disease  of  the  heart  muscle.  It  is  estimated  that  cardiomyopathy  accounts  for  5–10%  of  the  heart  failure  in  the  5–6  million  patients  carrying  that  diagnosis  in  the  United  States.  This  term  is  intended  to  exclude  cardiac  dysfunction  that  results  from  other  structural  heart  disease,  such  as  coronary  artery  disease,  primary  valve  disease,  or  severe  hypertension;  however,  in  general  usage,  the  phrase  ischemic  cardiomyopathy  is  sometimes  applied  to  describe  diffuse  dysfunction  attributed  to  multivessel  coronary  artery  disease,  and  nonischemic  cardiomyopathy  to  describe  cardiomyopathy  from  other  causes.  As  of  2013,  cardiomyopathies  are  defined  as  “disorders  characterized  by  morphologically  and  functionally  abnormal  myocardium  in  the  absence  of  any  other  disease  that  is  sufficient,  by  itself,  to  cause  the  observed  phenotype.”  It  was  further  specified  that  many  cardiomyopathies  will  be  attributable  to  genetic  disease.1