RT Book, Section A1 Loscalzo, Joseph A1 Libby, Peter A1 MacRae, Calum A. A2 Jameson, J. Larry A2 Fauci, Anthony S. A2 Kasper, Dennis L. A2 Hauser, Stephen L. A2 Longo, Dan L. A2 Loscalzo, Joseph SR Print(0) ID 1155972889 T1 Basic Biology of the Cardiovascular System T2 Harrison's Principles of Internal Medicine, 20e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259644016 LK accessmedicine.mhmedical.com/content.aspx?aid=1155972889 RD 2024/04/19 AB The heart forms early during embryogenesis (Fig. 232-1), circulating blood, nutrients, and oxygen to the other developing organs while continuing to grow and undergo complex morphogenetic changes. Early cardiac progenitors arise within crescent-shaped fields of lateral splanchnic mesoderm under the influence of multiple signals and migrate to the midline to form the linear heart tube: a single layer of endocardium and a single layer of cardiomyocyte precursors.