RT Book, Section A1 Kalantar-Zadeh, Kamyar A1 Kopple, Joel D. A2 Lerma, Edgar V. A2 Rosner, Mitchell H. A2 Perazella, Mark A. SR Print(0) ID 1149113459 T1 Chronic Renal Failure and the Uremic Syndrome: Nutritional Issues T2 CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259861055 LK accessmedicine.mhmedical.com/content.aspx?aid=1149113459 RD 2024/04/23 AB In patients with chronic kidney disease (CKD), as the glomerular filtration rate (GFR) declines, numerous nutritional and metabolic disorders develop, and the dietary requirements for many nutrients are altered. These disorders and alterations include, (1) diminished appetite or anorexia; (2) abnormalities in intestinal absorption of certain minerals, for example calcium, and other nutrients including some trace elements (eg, iron, selenium, zinc, and copper) and vitamins (eg, vitamin K, folic acid, riboflavin); (3) abnormalities in urinary, intestinal and dermal excretion of nutrients, including changes in microbiome; and (4) disorders of nutrient metabolism.