RT Book, Section
A1 Schaefer, G. Bradley
A1 Thompson, Jr., James N.
SR Print(0)
ID 1147722868
T1 Family History and Pedigree Analysis
T2 Medical Genetics: An Integrated Approach
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071664387
LK accessmedicine.mhmedical.com/content.aspx?aid=1147722868
RD 2024/04/19
AB Genetics  is  about  family  histories.  Whether  you  are  doing  experimental  breeding  of  mice  or  are  exploring  diversity  in  the  human  population,  genetic  traits  are  passed  in  family  lineages.  But  when  the  focus  is  on  a  molecular  or  a  developmental  question,  that  relationship  is  easily  taken  for  granted.  On  the  other  hand,  pedigrees  can  be  valuable  when  taking  a  broader  view  of  gene  expression,  phenotypic  variability,  and  patterns  of  transmission.  Pedigrees  can  yield  insights  that  single  mating  examples  fail  to  provide.  That  is  especially  true  for  human  genetics,  where  experimental  matings  typical  of  model  organism  studies  cannot  be  performed.