RT Book, Section
A1 Kasper, Dennis L.
A1 Fauci, Anthony S.
A1 Hauser, Stephen L.
A1 Longo, Dan L.
A1 Jameson, J. Larry
A1 Loscalzo, Joseph
SR Print(0)
ID 1128787415
T1 Ankylosing Spondylitis
T2 Harrison's Manual of Medicine, 19e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071828529
LK accessmedicine.mhmedical.com/content.aspx?aid=1128787415
RD 2024/04/19
AB Ankylosing  spondylitis  (AS)  belongs  to  the  family  of  spondyloarthritides  that  also  includes  reactive  arthritis  (Chap.  162),  psoriatic  arthritis  (Chap.  161),  enteropathic  arthritis  (Chap.  165)  juvenile-onset  spondyloarthritis,  and  undifferentiated  spondyloarthritis.  Classification  criteria  based  on  their  main  clinical  features  of  axial  spondyloarthritis  (Table  160-1)  and  peripheral  spondyloarthritis  (Table  160-2)  have  been  developed  that  aide  in  early  identification.  AS  is  a  chronic  and  progressive  inflammatory  disease  of  the  axial  skeleton  with  sacroiliitis  (usually  bilateral)  as  its  hallmark.  Peripheral  joints  and  extra-articular  structures  may  also  be  affected.  Most  frequently  presents  in  second  or  third  decade  more  commonly  in  men;  strong  association  with  histocompatibility  antigen  HLA-B27.