RT Book, Section A1 Kasper, Dennis L. A1 Fauci, Anthony S. A1 Hauser, Stephen L. A1 Longo, Dan L. A1 Jameson, J. Larry A1 Loscalzo, Joseph SR Print(0) ID 1128781937 T1 Sepsis and Septic Shock T2 Harrison's Manual of Medicine, 19e YR 2016 FD 2016 PB McGraw-Hill Education PP New York, NY SN 9780071828529 LK accessmedicine.mhmedical.com/content.aspx?aid=1128781937 RD 2024/04/24 AB Possibly harmful systemic response: Two or more of the following: – Fever (oral temperature >38°C [100.4°F]) or hypothermia (oral temperature 24 breaths/min)– Tachycardia (>90 beats/min)– Leukocytosis (>12,000/μL), leukopenia (10% bands; may have a noninfectious etiologySepsis (or severe sepsis): Harmful systemic response (including some degree of organ hypofunction) with a proven or suspected microbial etiologySeptic shock: Sepsis with hypotension (arterial bp <90 mmHg or 40 mmHg below pt’s normal bp for at least 1 h despite fluid resuscitation) or need for vasopressors to maintain systolic bp ≥90 mmHg or mean arterial bp ≥70 mmHg