RT Book, Section A1 Broudy, Virginia C. A1 Harrington, Robert D. A2 Kaushansky, Kenneth A2 Lichtman, Marshall A. A2 Prchal, Josef T. A2 Levi, Marcel M. A2 Press, Oliver W. A2 Burns, Linda J. A2 Caligiuri, Michael SR Print(0) ID 1121097775 T1 Hematologic Manifestations of Acquired Immunodeficiency Syndrome T2 Williams Hematology, 9e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071833004 LK accessmedicine.mhmedical.com/content.aspx?aid=1121097775 RD 2024/04/24 AB SUMMARYThe prevalence of HIV in the United States continues to rise as a result of the combined effects of a declining HIV death rate, and a sustained rate of new infections. Furthermore, HIV-infected patients on antiretroviral therapy can expect to live nearly as long as uninfected persons (within 5 years) providing ample time for individuals to develop AIDS-associated and non–AIDS-associated hematologic and oncologic conditions. HIV-infected individuals remain at increased risk of AIDS-defining malignancies such as Kaposi sarcoma, aggressive non-Hodgkin lymphoma, primary central nervous system lymphoma, and invasive cervical cancer and a number of non–AIDS-defining malignancies, including Hodgkin lymphoma, as well as anemia and thrombocytopenia. When individuals present with any of these hematologic or malignant illnesses it should be the standard of care to obtain HIV testing so as to provide optimal treatment to both the presenting illness and the HIV.