TY - CHAP M1 - Book, Section TI - Pathophysiology of Erectile Dysfunction A1 - Dave, Chirag N. A1 - Burnett, Arthur L. A1 - Herati, Amin S. A2 - Bhasin, Shalender A2 - O’Leary, Michael P. A2 - Basaria, Shehzad S. PY - 2021 T2 - Essentials of Men’s Health AB - Erectile dysfunction (ED) refers to the inability to achieve or maintain an erection that is sufficient for satisfactory intercourse. It is multidimensional and can arise from organic, relational, and/or psychogenic causes.1 The Massachusetts Male Aging Study (MMAS) reported a 52% prevalence of mild to moderate ED in men aged 40 to 70, and ED was found to be associated with age, health status, and emotional function.2,3 ED has detrimental effects on partner satisfaction and the couple’s quality of life. It was previously believed that most ED was psychogenic; however, more recent evidence shows that roughly 80% of ED is organic.3 ED may be a manifestation of endothelial dysfunction. Cardiovascular disease, poor general health status, diabetes, smoking, medications, and socioeconomic status are well-established risk factors for ED. Identification of these comorbid conditions offers the men’s health provider an opportunity to diagnose and intervene on conditions that may otherwise be asymptomatic. This chapter includes a brief discussion of the physiology of erection as it relates to a more complex discussion of the pathophysiology of ED. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/20 UR - accessmedicine.mhmedical.com/content.aspx?aid=1174514993 ER -