TY  - CHAP
M1  - Book, Section
TI  - Sickle Cell Disease
A1  - Bunn, H. Franklin
A2  - Aster, Jon C.
A2  - Bunn, H. Franklin
PY  - 2016
T2  - Pathophysiology of Blood Disorders, 2e
AB  - LEARNING  OBJECTIVESAfter  studying  this  chapter,  you  should  understand:The  inheritance  of  sickle  cell  disease  and  the  difference  between  hemoglobin  SS  homozygotes,  hemoglobin  AS  heterozygotes,  and  compound  heterozygotes  (hemoglobin  SC  and  hemoglobin  S/β-thalassemia).The  molecular  basis  for  polymerization  of  deoxyhemoglobin  S.The  process  of  sickle  vaso-occlusion.The  clinical  manifestations  of  sickle  cell  disease:  acute  pain  crises  and  progressive  organ  damage.The  treatment  of  sickle  cell  disease:  supportive  care  and  prevention  of  sickling.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1177742316
ER  -