TY - CHAP M1 - Book, Section TI - Anemia Resulting from other Nutritional Deficiencies A1 - Green, Ralph A2 - Kaushansky, Kenneth A2 - Lichtman, Marshall A. A2 - Prchal, Josef T. A2 - Levi, Marcel M. A2 - Press, Oliver W. A2 - Burns, Linda J. A2 - Caligiuri, Michael Y1 - 2015 N1 - T2 - Williams Hematology, 9e AB - SUMMARYThe anemia that results from deficiencies of vitamin B12, folic acid (Chap. 41) or iron (Chap. 43) are, in general, clearly defined and are relatively common. In contrast, characteristics of anemia that may occur with deficiencies of the other vitamins and minerals are poorly defined and relatively rare in humans. When present, they usually exist not as isolated deficiencies of one vitamin or one mineral, but rather, as a combination of deficiencies resulting from malnutrition or malabsorption. In this context, it is difficult to deduce which abnormalities are the result of which deficiency. Studies in experimental animals may not accurately reflect the role of micronutrients in humans. Accordingly, our knowledge of the effects of many micronutrients on hematopoiesis is fragmentary and based on clinical observations and interpretations that may be flawed. Inborn metabolic errors that affect single micronutrient pathways may shed light on specific effects of those micronutrients on hematopoiesis. Daily requirements of some micronutrients are available at: http://www.nal.usda.gov/fnic/dga/rda.pdf, and levels normally found in serum, red cells, and leukocytes are shown in Table 44–1. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1121092935 ER -