TY  - CHAP
M1  - Book, Section
TI  - Chapter 175. General Considerations of Bacterial Diseases
A1  - Craft, Noah
A2  - Goldsmith, Lowell A.
A2  - Katz, Stephen I.
A2  - Gilchrest, Barbara A.
A2  - Paller, Amy S.
A2  - Leffell, David J.
A2  - Wolff, Klaus
Y1  - 2012
N1  - 
T2  - Fitzpatrick's Dermatology in General Medicine, 8e
AB  - |PrintBacterial  Skin  Diseases  at  a  GlanceBacteria  cause  disease  by  direct  invasion  of  tissues,  by  secreting  toxins,  and  by  causing  immunologic  consequences  that  result  in  disease.The  innate  immune  system  is  critical  in  the  initial  defense  against  bacterial  entry  into  the  skin.The  virulence  and  pathogenicity  of  bacteria  is  related  to  their  ability  to  avoid  activating  the  innate  immune  system  or  resisting  killing  within  immune  effector  cells.Immunosuppression,  especially  neutropenia,  puts  the  host  at  high  risk  for  bacterial  infections;  some  infections  are  rare  except  in  the  immunocompromised  host.Consideration  of  host  factors  and  pathogen  virulence  factors  are  critical  to  choose  a  safe  and  effective  therapy  against  bacterial  infections.There  are  many  noninfectious  conditions  that  can  mimic  the  clinical  presentations  of  bacterial  infections.  Consider  the  noninfectious  differential  diagnoses  carefully.The  use  of  up-to-date  computer  based  resources  for  antibiotic  resistance  trends  and  best-practice  guidelines  is  important  when  choosing  empiric  antimicrobial  therapy.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/25
UR  - accessmedicine.mhmedical.com/content.aspx?aid=56081413
ER  -