TY - CHAP M1 - Book, Section TI - Chapter 144. Hematologic Diseases A1 - Piette, Warren W. A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - |PrintHematologic Diseases at a GlanceMucocutaneous changes (i.e., pallor, jaundice, flushing, erythema, and cyanosis) often predict underlying hematologic pathology.Anemia is best differentiated by mean corpuscular volume value.Megaloblastic anemia of vitamin B12 deficiency is distinguished from folate deficiency by lack of neurologic signs in folate deficiency.Carcinoid tumor results in flushing, typically for 10 minutes or less; in comparison, flushing from mastocytosis lasts 30 minutes or more.Polycythemia vera presents with acrocyanosis, aquagenic pruritus, urticaria, Sweet syndrome, and purpura.The morphologic diagnosis of purpura begins with three Ps: (1) is the lesion purpuric, (2) is it primary, and (3) is it palpable?Leukemia cutis is a localized or disseminated skin infiltration by leukemic cells. It is a sign of dissemination or systemic disease or relapsing leukemia. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/20 UR - accessmedicine.mhmedical.com/content.aspx?aid=56071604 ER -