TY - CHAP M1 - Book, Section TI - Chapter 113. Epithelial Precancerous Lesions A1 - Duncan, Karynne O. A1 - Geisse, John K. A1 - Leffell, David J. A2 - Goldsmith, Lowell A. A2 - Katz, Stephen I. A2 - Gilchrest, Barbara A. A2 - Paller, Amy S. A2 - Leffell, David J. A2 - Wolff, Klaus Y1 - 2012 N1 - T2 - Fitzpatrick's Dermatology in General Medicine, 8e AB - A precancerous or premalignant lesion is one that has a strong likelihood of transforming into a malignancy. There is much debate about the validity of the concept of precancerous lesions, and the terminology has been confusing.1–4 Lesions discussed in this chapter are those that have a clinically demonstrated potential to become invasive carcinomas and are characterized by histologic atypia confined to the epidermis. The focus is only on the precancerous keratinocyte lesions and not on those of other epithelial cells such as the melanocyte, Merkel, and appendageal cells. Discussion of malignancies and premalignancies associated with these cells can be found in (Chapters 119, 120, and 123) respectively. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56058492 ER -