TY - CHAP M1 - Book, Section TI - Chapter 43. Disorders of Sex Development A1 - Baskin, Laurence S. A2 - McAninch, Jack W. A2 - Lue, Tom F. Y1 - 2013 N1 - T2 - Smith & Tanagho's General Urology, 18e AB - What defines our sexuality is a complex interaction between our genetic makeup, environmental stimulus, and cultural influences. The origins of our sexuality occur at the time of conception when the genetic material from two sources of the opposite sex coalesces into a new individual. From that moment, sexual differentiation occurs by a highly organized process. Sex chromosomes and autosomes dictate the development of gonads; the gonads in turn produce hormones, which then direct the development of the internal and external genitalia. Disorders of sex development (DSD) or differentiation arise from abnormalities in chromosomes, gonadal development, or hormonal production/activity. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=56951354 ER -