TY  - CHAP
M1  - Book, Section
TI  - Renal Tubular Disease
A1  - Kasper, Dennis L.
A1  - Fauci, Anthony S.
A1  - Hauser, Stephen L.
A1  - Longo, Dan L.
A1  - Jameson, J. Larry
A1  - Loscalzo, Joseph
Y1  - 2016
N1  - 
T2  - Harrison's Manual of Medicine, 19e
AB  - Tubulointerstitial  diseases  constitute  a  diverse  group  of  acute  and  chronic,  hereditary  and  acquired  disorders  involving  the  renal  tubules  and  supporting  structures  (Table  143-1).  Functionally,  they  may  result  in  a  wide  variety  of  physiologic  phenotypes,  including  nephrogenic  diabetes  insipidus  (DI)  with  polyuria,  non-anion-gap  metabolic  acidosis,  salt  wasting,  and  hypo-  or  hyperkalemia.  Azotemia  is  common,  owing  to  associated  glomerular  fibrosis  and/or  ischemia.  Compared  with  glomerulopathies,  proteinuria  and  hematuria  are  less  dramatic,  and  hypertension  is  less  common.  The  functional  consequences  of  tubular  dysfunction  are  outlined  in  Table  143-2.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1128786730
ER  -