TY  - CHAP
M1  - Book, Section
TI  - Cellular Therapy in Allogeneic Hematopoietic Cell Transplantation
A1  - Thompson, Philip A.
A1  - Rezvani, Katayoun
A1  - Kebriaei, Partow
A2  - Kantarjian, Hagop M.
A2  - Wolff, Robert A.
Y1  - 2016
N1  - 
T2  - The MD Anderson Manual of Medical Oncology, 3e
AB  - The  efficacy  of  allogeneic  hematopoietic  cell  transplantation  (HCT)  in  hematologic  malignancies  can  in  large  part  be  attributed  to  a  graft-versus-tumor  (GVT)  effect,  by  which  the  donor  immune  system  achieves  immunologic  control  of  the  tumor.  As  such,  it  is  the  prototype  of  cellular  therapy.  The  human  leukocyte  antigen  (HLA)  system  is  fundamental  to  transplant  biology.  The  HLAs  are  highly  polymorphic  proteins  that  have  a  key  role  in  antigen  presentation  and  immunoregulation.  Class  I  HLAs  are  expressed  on  the  surfaces  of  all  nucleated  cells;  class  II  are  expressed  on  specialized  antigen-presenting  cells  (APCs),  such  as  macrophages,  dendritic  cells,  and  B  cells.  
SN  - 
PB  - McGraw-Hill Medical
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1126741412
ER  -