TY - CHAP M1 - Book, Section TI - Disordered Sleep and Reproductive Dysfunction A1 - Yuen, Fiona A1 - James, Amy A1 - Wallace, Jeanne A1 - Liu, Peter Y. A2 - Bhasin, Shalender A2 - O’Leary, Michael P. A2 - Basaria, Shehzad S. PY - 2021 T2 - Essentials of Men’s Health AB - Normal sleep in adult humans is organized into cycles of non–rapid eye movement (NREM) sleep alternating with rapid eye movement (REM) sleep. NREM sleep is further divided into stages 1, 2, and 3, which are transitions as sleep deepens and which represent progressive slowing of the electroencephalogram (EEG). Stages 1, 2, and 3 of NREM sleep and REM sleep each can be identified by eye movements, characteristic EEG frequencies and patterns, and muscle tone. Stage 3 NREM sleep, also known as “slow wave sleep” (SWS), is associated with decreased heart rate, blood pressure, and sympathetic nervous system activity, as well as with decreased cerebral glucose utilization, growth hormone and prolactin release, and inhibition of cortisol secretion. Accordingly, SWS is the stage of sleep that is most highly metabolically and hormonally active. On the other hand, REM sleep is required for memory consolidation, and is the stage of sleep during which vivid dreaming occurs. Staging of sleep is important because different sleep stages may serve different biological functions. Each sleep cycle is approximately 90 to 120 minutes in duration. Stage 3 NREM sleep occurs predominately during the first half of the biological night (based on each individual’s circadian rhythm), whereas REM periods typically increase in length and occurrence as the biological night progresses (Fig. 11-1). SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/25 UR - accessmedicine.mhmedical.com/content.aspx?aid=1174515611 ER -