TY - CHAP M1 - Book, Section TI - Family History and Pedigree Analysis A1 - Schaefer, G. Bradley A1 - Thompson, Jr., James N. PY - 2017 T2 - Medical Genetics: An Integrated Approach AB - Genetics is about family histories. Whether you are doing experimental breeding of mice or are exploring diversity in the human population, genetic traits are passed in family lineages. But when the focus is on a molecular or a developmental question, that relationship is easily taken for granted. On the other hand, pedigrees can be valuable when taking a broader view of gene expression, phenotypic variability, and patterns of transmission. Pedigrees can yield insights that single mating examples fail to provide. That is especially true for human genetics, where experimental matings typical of model organism studies cannot be performed. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessmedicine.mhmedical.com/content.aspx?aid=1147722868 ER -