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Clinical Neurology is intended to introduce medical students and house officers to the field of neurology and to serve them as a continuing resource in their work on the wards and in the clinics. This eighth edition reflects the book's evolution over more than 20 years and is based on the authors' clinical experience and teaching at a variety of institutions in the United States and United Kingdom.

The new edition has been extensively revised and thoroughly updated. Major changes include new introductory chapters on the neurologic history and examination and on laboratory investigations; state-of-the-art discussions of the molecular basis of Alzheimer disease and other dementias, spinocerebellar ataxias, motor neuron disease, muscular dystrophies, Parkinson disease, Huntington disease, multiple sclerosis, epilepsy, and stroke; and coverage of recent advances in the treatment of neurologic complications of general medical disorders, headache and facial pain, movement disorders, seizures, and cerebrovascular disease, among other conditions.

Not least—and probably most noticeable—of the new features is the incorporation of full-color illustrations, which should help to clarify neuroanatomic principles, clinical–anatomic correlations, pathophysiologic mechanisms, and clinical signs.

Many of our colleagues have generously provided advice or material for this edition. In this regard we are especially grateful to Drs. Megan M. Burns, Allitia DiBernardo, Vanja Douglas, Alisa Gean, J. Handwerke, Rock Heyman, Justin Hill, Charles Jungreis, James Keane, Nancy J. Newman, and Howard Rowley. The staff at McGraw-Hill have been enormously helpful in the editing and production of this volume.

Finally, we hope that students, house officers, and other practitioners who read this book will find it helpful in demystifying and communicating the excitement of neurology.

David A. Greenberg
Michael J. Aminoff
Roger P. Simon
Novato, San Francisco, and Atlanta
May 2012

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