Limbic encephalitis (Chap. 101) Coronal (A, B), axial fluid-attenuated inversion recovery (FLAIR) (C, D), and axial T2-weighted (E) MR images demonstrate abnormal high signal involving the bilateral mesial temporal lobes (arrowheads) including the hippocampi (left greater than right) without significant mass effect (arrows). There was no enhancement on postgadolinium images (not shown).
CNS tuberculosis (Chap. 165)
Axial T2-weighted MRI (A) demonstrates multiple lesions (arrows) with peripheral high signal and central low signal, located predominantly in the cortex and subcortical white matter, as well as in the basal ganglia.
Axial T1-weighted MR images postgadolinium (B, C) demonstrate ring enhancement of the lesions (arrows) and additional lesions in the subarachnoid space (arrowheads).
Sagittal T2-weighted MR image of the cervical spine (D) demonstrates a hypointense lesion in the subarachnoid space at the level of T5 (arrow).
Sagittal T1-weighted MR image postgadolinium of the cervical spine (E) demonstrates enhancement of the lesion in the subarachnoid space at the level of T5 (arrow).
Neurosyphilis (Chap. 169)
Axial T2-weighted MR images (A, B) demonstrate well-defined areas of abnormal high signal in the basal ganglia bilaterally and in a wedge-shaped distribution in the right parietal lobe (arrows).
Axial (C, D) T1-weighted images postgadolinium.
Coronal (E, F) T1-weighted images postgadolinium demonstrate irregular ring enhancement of the lesions (arrows).
Neurosyphilis (Chap. 169)
Axial T2-weighted MRI (A) demonstrates a dural-based, peripherally hyperintense and centrally hypointense lesion located lateral to the left frontal lobe (arrow).
Axial (B) and coronal (C) T1-weighted MR images postgadolinium demonstrate peripheral enhancement of the lesion (arrows).
Histoplasmosis of the pons (Chap. 199)
Axial FLAIR (A) and T2-weighted (B) MR images demonstrate a low signal mass in the right pons (arrows) with surrounding vasogenic edema.
Axial T1-weighted MR image postgadolinium (C) demonstrates ring enhancement of the lesion in the right pons (arrow). Of note, there was no evidence of restricted diffusion (not shown).
Coccidiomycosis meningitis (Chap. 200)
Axial postcontrast CT (A) and axial (B) and coronal (C) T1-weighted MR images postgadolinium demonstrate enhancement of the perimesencephalic cisterns (arrows), as well as the sylvian and interhemispheric fissures.
Candidiasis in a newborn (Chap. 203)
Axial T2-weighted MR image (A) demonstrates multiple punctate foci of low signal diffusely distributed in the brain parenchyma (arrowhead).
Axial T1-weighted MR images postgadolinium (B, C) demonstrate marked enhancement of the lesions (arrowheads).
ADC map (D, E) demonstrates restricted diffusion of water molecules in the lesions (arrowheads).
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