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Give an antidote (if available) when there is reasonable certainty of a specific diagnosis (Table 38–3). Be aware that some antidotes themselves may have serious side effects. The indications and dosages for specific antidotes are discussed in the respective sections for specific toxins.

Table 38–3.Some toxic agents for which there are specific antidotes.1
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Dart  RC  et al. Expert consensus guidelines for stocking of antidotes in hospitals that provide emergency care. Ann Emerg Med. 2018 Mar;71(3):314–25.
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Dzeshka  MS  et al. Direct oral anticoagulant reversal: how, when and issues faced. Expert Rev Hematol. 2017 Nov;10(11):1005–22.
[PubMed: 28901221]  
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Schwenk  M. Chemical warfare agents. Classes and targets. Toxicol Lett. 2018 Sep 1;293:253–63.
[PubMed: 29197625]  

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