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About 10% of lymphomas present in the head and neck. Multiple rubbery nodes, especially in young adults or in patients who have AIDS, are suggestive of lymphoma. A thorough physical examination may demonstrate other sites of nodal or organ involvement. FNA biopsy may be diagnostic, but open biopsy is often required to determine architecture and an appropriate treatment course.

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Cabeçadas  J  et al. Lymphomas of the head and neck region: an update. Virchows Arch. 2019 Jun;474(6):649–65.
[PubMed: 30778677]
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Oishi  N  et al. Head and neck lymphomas in HIV patients: a clinical perspective. Int Arch Otorhinolaryngol. 2017 Oct;21(4):399–407.
[PubMed: 29018505]

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