NON-BOTANICAL DIETARY SUPPLEMENTS
In the 7-year follow-up to the KUDOS study, in which mothers received either 600 mg/day of DHA or a placebo beginning at 14.5 weeks of gestation until delivery, no consistent long-term benefits were sustained into childhood. In a 2019 study, supplementation with 900 mg omega-3 fatty acids during early pregnancy did not result in a lower incidence of early preterm delivery or a higher incidence of interventions in postterm deliveries.
A clinical trial of CoQ10 (200 mg) and vitamin E (400 international units) in 89 patients with polycystic ovarian syndrome found benefit on serum fasting blood sugar and insulin levels, as well as insulin resistance and total testosterone levels.
Melatonin given as a nightly dose of 3 mg did not prevent delirium in non-intensive care unit hospitalized patients or improve subjective or objective sleep.
The benefits of acupuncture in managing postoperative pain were shown in a 2019 study of abdominal surgery.
A pilot study found that intraoperative laser acupuncture stimulation of P6 acupoints combined with antiemetic medication prophylaxis decreased postoperative nausea and rescue antiemetic medication need in patients who underwent a laparoscopic cholecystectomy.
In 2020, Centers for Medicare & Medicaid Services approved coverage of acupuncture for Medicare patients with chronic low back pain. Many other insurance providers cover acupuncture.