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Plate 1.

Rectal mucosal biopsy specimen from a patient with dysentery caused by shigellosis. There is considerable mucosal inflammation caused by infiltration with polymorphonuclear leukocytes and mononuclear cells, as well as substantial damage to surface epithelial cells. However, mucosal architecture is generally preserved with straight, closely adjacent crypts. A crypt microabscess is seen on the right.

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Plate 2.

Rectal mucosal biopsy specimen from a patient with dysenteric stools caused by a flare of chronic ulcerative colitis. The mucosa is heavily infiltrated with polymorphonuclear leukocytes and mononuclear cells. In contrast to Plate 1, mucosal architecture is markedly distorted, with substantial reduction in crypts and distortion of those that remain.

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Plate 3.

Endoscopic appearance of colonic ischemia. (Used with permission from David Stockwell, MD.)

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Plate 4.

Esophageal carcinoma. Fused PET-CT image shows a "hot spot" (black arrow) at the level of the distal esophagus corresponding to squamous cell carcinoma. Note the hepatic metastasis (white arrowhead).

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Plate 5.

Colonic polyp. Three-dimensional endoluminal reconstructed image confirms the presence of a colonic polyp (arrow). (For corresponding axial MDCT image, see Figure 9–17 in the text.)

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Plate 6.

Severe erosive esophagitis with peptic stricture.

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Plate 7.

Esophageal stricture prior to dilation.

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Plate 8.

Postdilation appearance of esophageal stricture shown in Plate 7.

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Plate 9.

Endoscopic appearance of Barrett esophagus.

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Plate 10.

Histopathologic findings in nondysplastic Barrett esophagus. Note the glandular epithelium containing goblet cells. (Used with permission from Jason Hornick, MD, PhD, Brigham and Women's Hospital.)

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Plate 11.

Histopathologic findings of low-grade dysplasia in Barrett esophagus. The surface epithelium displays nuclear stratification, limited to the lower half of the cytoplasm. (Used with permission from Jason Hornick, MD, PhD, Brigham and Women's Hospital.)

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Plate 12.

Histopathologic findings of high-grade dysplasia in Barrett esophagus. There is full-thickness nuclear stratification and the mucosa has a villous appearance. (Used with permission from Jason Hornick, MD, PhD, Brigham and Women's Hospital.)

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